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Title: LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants

Journal Article · · Cell Reports

Research Organization:
Argonne National Laboratory (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
DOE - Office Of Science; INDUSTRY
OSTI ID:
1900749
Journal Information:
Cell Reports, Vol. 39, Issue (7)
Country of Publication:
United States
Language:
ENGLISH

References (51)

Immunity to SARS-CoV-2 variants of concern journal March 2021
Extremely potent human monoclonal antibodies from COVID-19 convalescent patients journal April 2021
Five reasons why COVID herd immunity is probably impossible journal March 2021
Emergence of a Highly Fit SARS-CoV-2 Variant journal December 2020
SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies journal October 2020
SARS-CoV-2 Neutralizing Antibody LY-CoV555 in Outpatients with Covid-19 journal January 2021
MolProbity : all-atom structure validation for macromolecular crystallography journal December 2009
Persistence and Evolution of SARS-CoV-2 in an Immunocompromised Host journal December 2020
SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness journal August 2020
Twelve years of SAMtools and BCFtools journal January 2021
Covid-19: variants and vaccination journal March 2021
Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England journal March 2021
Antibody evasion by the P.1 strain of SARS-CoV-2 journal March 2021
How good are my data and what is the resolution? journal June 2013
Effect of Bamlanivimab as Monotherapy or in Combination With Etesevimab on Viral Load in Patients With Mild to Moderate COVID-19: A Randomized Clinical Trial journal February 2021
Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy journal July 2020
Early Treatment for Covid-19 with SARS-CoV-2 Neutralizing Antibody Sotrovimab journal November 2021
Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail journal June 2020
SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies journal April 2021
Structure-based design of prefusion-stabilized SARS-CoV-2 spikes journal July 2020
Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2 journal July 2020
Antibody evasion properties of SARS-CoV-2 Omicron sublineages journal March 2022
Neutralizing antibodies for the treatment of COVID-19 journal December 2020
The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates journal May 2021
SARS-CoV-2 spike variants exhibit differential infectivity and neutralization resistance to convalescent or post-vaccination sera journal April 2021
Fast and accurate long-read alignment with Burrows–Wheeler transform journal January 2010
Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing journal September 2020
Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike journal July 2020
Identification of SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization journal March 2021
The emerging plasticity of SARS-CoV-2 journal March 2021
Geographic and Genomic Distribution of SARS-CoV-2 Mutations journal July 2020
Transmission of SARS-CoV-2 on mink farms between humans and mink and back to humans journal November 2020
Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. journal October 1996
Establishment and validation of a pseudovirus neutralization assay for SARS-CoV-2 journal January 2020
Emerging SARS-CoV-2 mutation hot spots include a novel RNA-dependent-RNA polymerase variant journal April 2020
Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody journal May 2020
Spike mutation D614G alters SARS-CoV-2 fitness journal October 2020
Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody journal February 2021
The effect of spike mutations on SARS-CoV-2 neutralization journal March 2021
Processing of Structurally Heterogeneous Cryo-EM Data in RELION book January 2016
GISAID: Global initiative on sharing all influenza data – from vision to reality journal March 2017
Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER journal March 2012
Convalescent-Phase Sera and Vaccine-Elicited Antibodies Largely Maintain Neutralizing Titer against Global SARS-CoV-2 Variant Spikes journal June 2021
Sixteen novel lineages of SARS-CoV-2 in South Africa journal February 2021
Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity journal March 2021
Data processing and analysis with the autoPROC toolbox journal March 2011
Generation of VSV pseudotypes using recombinant ΔG-VSV for studies on virus entry, identification of entry inhibitors, and immune responses to vaccines journal November 2010
Overview of the CCP 4 suite and current developments journal March 2011
Neutralization of SARS-CoV-2 spike 69/70 deletion, E484K and N501Y variants by BNT162b2 vaccine-elicited sera journal February 2021
Engineering SARS-CoV-2 using a reverse genetic system journal January 2021
Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant journal October 2020