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April 2014 |
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Structural basis of cellular dNTP regulation by SAMHD1
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Mutational consequences of dNTP pool imbalances in E. coli
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Features and development of Coot
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Structure of dNTP-inducible dNTP triphosphohydrolase: insight into broad specificity for dNTPs and triphosphohydrolase-type hydrolysis
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PHENIX: a comprehensive Python-based system for macromolecular structure solution
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GTP Is the Primary Activator of the Anti-HIV Restriction Factor SAMHD1
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July 2013 |
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Solution Structure of the dATP-Inactivated Class I Ribonucleotide Reductase From Leeuwenhoekiella blandensis by SAXS and Cryo-Electron Microscopy
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July 2021 |
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Biochemical Characterization of TT1383 from Thermus thermophilus Identifies a Novel dNTP Triphosphohydrolase Activity Stimulated by dATP and dTTP
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August 2004 |
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Characterization of the Deoxynucleotide Triphosphate Triphosphohydrolase (dNTPase) Activity of the EF1143 Protein from Enterococcus faecalis and Crystal Structure of the Activator-Substrate Complex
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Enzymatic Cleavage of Deoxyguanosine Triphosphate to Deoxyguanosine and Tripolyphosphate
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July 1958 |
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Structural analysis of the dNTP triphosphohydrolase PA1124 from Pseudomonas aeruginosa
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MolProbity : all-atom structure validation for macromolecular crystallography
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December 2009 |
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Phaser crystallographic software
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July 2007 |
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Aicardi-Goutières Syndrome Gene and HIV-1 Restriction Factor SAMHD1 Is a dGTP-regulated Deoxynucleotide Triphosphohydrolase
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November 2011 |
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Hypermutability and error catastrophe due to defects in ribonucleotide reductase
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October 2013 |
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Coupling between bacterioplankton species composition, population dynamics, and organic matter degradation
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DNA binding properties of the deoxyguanosine triphosphate triphosphohydrolase of Escherichia coli.
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Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools
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Cryo-EM structure of phosphodiesterase 6 reveals insights into the allosteric regulation of type I phosphodiesterases
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February 2019 |
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A continuous spectrophotometric enzyme-coupled assay for deoxynucleoside triphosphate triphosphohydrolases
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March 2016 |
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Inference of Macromolecular Assemblies from Crystalline State
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September 2007 |
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Substrate Specificity of SAMHD1 Triphosphohydrolase Activity Is Controlled by Deoxyribonucleoside Triphosphates and Phosphorylation at Thr592
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September 2016 |
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A Novel Mutator of Escherichia coli Carrying a Defect in the dgt Gene, Encoding a dGTP Triphosphohydrolase
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September 2008 |
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Two dNTP triphosphohydrolases from Pseudomonas aeruginosa possess diverse substrate specificities
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June 2009 |
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New tools for automated high-resolution cryo-EM structure determination in RELION-3
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November 2018 |
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Human Alkyladenine DNA Glycosylase Uses Acid−Base Catalysis for Selective Excision of Damaged Purines †
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October 2003 |
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CTFFIND4: Fast and accurate defocus estimation from electron micrographs
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November 2015 |
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Transition State Charge Stabilization and Acid–Base Catalysis of mRNA Cleavage by the Endoribonuclease RelE
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November 2015 |
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The HD domain defines a new superfamily of metal-dependent phosphohydrolases
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December 1998 |
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Structure of Escherichia coli dGTP Triphosphohydrolase : A HEXAMERIC ENZYME WITH DNA EFFECTOR MOLECULES
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Beam image-shift accelerated data acquisition for near-atomic resolution single-particle cryo-electron tomography
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March 2021 |
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Probing the Catalytic Mechanism and Inhibition of SAMHD1 Using the Differential Properties of Rp- and Sp-dNTPαS Diastereomers
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May 2021 |
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HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
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The purification and properties of deoxyguanosine triphosphate triphosphohydrolase from Escherichia coli.
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January 1988 |
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The deoxynucleotide triphosphohydrolase SAMHD1 is a major regulator of DNA precursor pools in mammalian cells
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June 2020 |
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DeepEMhancer: a deep learning solution for cryo-EM volume post-processing
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July 2021 |
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UCSF ChimeraX: Meeting modern challenges in visualization and analysis: UCSF ChimeraX Visualization System
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September 2017 |
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Towards automated crystallographic structure refinement with phenix.refine
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March 2012 |
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UCSF Chimera?A visualization system for exploratory research and analysis
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DNA building blocks: keeping control of manufacture
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January 2010 |
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A glutaredoxin domain fused to the radical-generating subunit of ribonucleotide reductase (RNR) functions as an efficient RNR reductant
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August 2018 |
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Mechanism of allosteric activation of SAMHD1 by dGTP
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October 2013 |
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GTP activator and dNTP substrates of HIV-1 restriction factor SAMHD1 generate a long-lived activated state
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April 2014 |
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Structural Basis of Allosteric Activation of Sterile α Motif and Histidine-Aspartate Domain-containing Protein 1 (SAMHD1) by Nucleoside Triphosphates
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October 2014 |
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Cost of rNTP/dNTP pool imbalance at the replication fork
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July 2013 |
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Mechanistic cross-talk between DNA/RNA polymerase enzyme kinetics and nucleotide substrate availability in cells: Implications for polymerase inhibitor discovery
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September 2020 |
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Escherichia coli dGTP triphosphohydrolase is inhibited by gene 1.2 protein of bacteriophage T7.
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September 1988 |
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Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase
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November 2013 |
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Nuclease Activity of the Human SAMHD1 Protein Implicated in the Aicardi-Goutières Syndrome and HIV-1 Restriction*
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March 2013 |
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Mechanisms of Allosteric Activation and Inhibition of the Deoxyribonucleoside Triphosphate Triphosphohydrolase from Enterococcus faecalis
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December 2013 |
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New tools for the analysis and validation of cryo-EM maps and atomic models
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September 2018 |
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Class Id ribonucleotide reductase utilizes a Mn2(IV,III) cofactor and undergoes large conformational changes on metal loading
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August 2019 |
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The gene 1.2 protein of bacteriophage T7 interacts with the Escherichia coli dGTP triphosphohydrolase to form a GTP-binding protein.
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March 1990 |
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The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity
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April 2019 |
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Leeuwenhoekiella blandensis sp. nov., a genome-sequenced marine member of the family Flavobacteriaceae
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July 2006 |
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A unique deoxyguanosine triphosphatase is responsible for the optA1 phenotype of Escherichia coli.
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April 1988 |