skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor a

Journal Article · · Nat. Commun.

Research Organization:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
DOE - Office Of Science; National Institutes of Health (NIH)
OSTI ID:
1878387
Journal Information:
Nat. Commun., Vol. 13
Country of Publication:
United States
Language:
ENGLISH

References (60)

Complexity and Diversity of the Mammalian Sialome Revealed by Nidovirus Virolectins journal June 2015
Nothing in Glycobiology Makes Sense, except in the Light of Evolution journal September 2006
Biomedical Differences Between Human and Nonhuman Hominids: Potential Roles for Uniquely Human Aspects of Sialic Acid Biology journal February 2011
Biological roles of glycans journal August 2016
Absence of capsule reveals glycan-mediated binding and recognition of salivary mucin MUC7 by Streptococcus pneumoniae journal August 2015
Binding of the Streptococcal Surface Glycoproteins GspB and Hsa to Human Salivary Proteins journal March 2006
Streptococcal Siglec-like adhesins recognize different subsets of human plasma glycoproteins: implications for infective endocarditis journal June 2018
Binding of the Streptococcus gordonii surface glycoproteins GspB and Hsa to specific carbohydrate structures on platelet membrane glycoprotein Ibα: Specific GPIbα binding by BR of GspB and Hsa journal September 2005
A serine-rich glycoprotein of Streptococcus sanguis mediates adhesion to platelets via GPIb journal April 2005
Update on Infective Endocarditis journal April 2006
A role for glycosylated serine-rich repeat proteins in Gram-positive bacterial pathogenesis: Role for SRRPs in Gram-positive pathogenesis journal June 2012
A Structural Model for Binding of the Serine-Rich Repeat Adhesin GspB to Host Carbohydrate Receptors journal July 2011
Contribution of Sialic Acid-Binding Adhesin to Pathogenesis of Experimental Endocarditis Caused by Streptococcus gordonii DL1 journal January 2006
Tandem sialoglycan-binding modules in a Streptococcus sanguinis serine-rich repeat adhesin create target dependent avidity effects journal October 2020
Structural Basis for Sialoglycan Binding by the Streptococcus sanguinis SrpA Adhesin journal February 2016
Structure based virtual screening identifies small molecule effectors for the sialoglycan binding protein Hsa journal October 2020
Molecular recognition of sialoglycans by streptococcal Siglec-like adhesins: toward the shape of specific inhibitors journal January 2021
Oral Streptococci Utilize a Siglec-Like Domain of Serine-Rich Repeat Adhesins to Preferentially Target Platelet Sialoglycans in Human Blood journal December 2014
Human Low-Molecular-Weight Salivary Mucin Expresses the Sialyl Lewis x Determinant and Has L-Selectin Ligand Activity journal March 1998
Salivary MUC7 is a major carrier of blood group I type O-linked oligosaccharides serving as the scaffold for sialyl Lewis x journal November 2008
Recognition of specific sialoglycan structures by oral streptococci impacts the severity of endocardial infection journal June 2019
Structures of the Streptococcus sanguinis SrpA Binding Region with Human Sialoglycans Suggest Features of the Physiological Ligand journal October 2016
The Streptococcus gordonii Surface Proteins GspB and Hsa Mediate Binding to Sialylated Carbohydrate Epitopes on the Platelet Membrane Glycoprotein Ib  journal October 2004
Role of the serine-rich surface glycoprotein GspB of Streptococcus gordonii in the pathogenesis of infective endocarditis journal October 2008
The sequence signature of an Ig-fold journal July 2013
Conformational selection or induced-fit? 50 years of debate resolved journal September 2011
Role of Induced Fit in Enzyme Specificity: A Molecular Forward/Reverse Switch journal June 2008
A novel sialic acid-binding adhesin present in multiple species contributes to the pathogenesis of Infective endocarditis journal January 2021
Streptococcus oralis subsp. dentisani Produces Monolateral Serine-Rich Repeat Protein Fibrils, One of Which Contributes to Saliva Binding via Sialic Acid journal July 2019
Two Arginine Residues of Streptococcus gordonii Sialic Acid-Binding Adhesin Hsa Are Essential for Interaction to Host Cell Receptors journal April 2016
Crystal Structure of the N-Terminal Domain of Sialoadhesin in Complex with 3′ Sialyllactose at 1.85 Å Resolution journal April 1998
Characterization of the Sialic Acid-binding Site in Sialoadhesin by Site-directed Mutagenesis journal April 1996
High Resolution Crystal Structures of Siglec-7: INSIGHTS INTO LIGAND SPECIFICITY IN THE SIGLEC FAMILY journal November 2002
Structural basis for sulfation-dependent self-glycan recognition by the human immune-inhibitory receptor Siglec-8 journal June 2016
Oral Microbial Communities: Biofilms, Interactions, and Genetic Systems journal October 2000
A mutation in human CMP-sialic acid hydroxylase occurred after the Homo-Pan divergence journal September 1998
Structural basis of glycan specificity of P[19] VP8*: Implications for rotavirus zoonosis and evolution journal November 2017
Structural Basis and Evolution of Glycan Receptor Specificities within the Polyomavirus Family journal August 2020
Engineering the carbohydrate-binding site of Epa1p from Candida glabrata: generation of adhesin mutants with different carbohydrate specificity journal July 2014
Tailoring a Novel Sialic Acid-Binding Lectin from a Ricin-B Chain-like Galactose-Binding Protein by Natural Evolution-Mimicry journal December 2006
Mutational Tuning of Galectin-3 Specificity and Biological Function journal November 2010
Directed Evolution of Lectins with Sugar-binding Specificity for 6-Sulfo-galactose journal June 2012
Tailoring GalNAcα1-3Galβ-specific lectins from a multi-specific fungal galectin: dramatic change of carbohydrate specificity by a single amino-acid substitution journal June 2013
Mutated Leguminous Lectin Containing a Heparin-Binding like Motif in a Carbohydrate-Binding Loop Specifically Binds to Heparin journal December 2015
Engineering of the glycan-binding specificity of Agrocybe cylindracea galectin towards α(2,3)-linked sialic acid by saturation mutagenesis journal August 2011
Engineering of recombinant Wisteria floribunda agglutinin specifically binding to GalNAcβ1,4GlcNAc (LacdiNAc) journal June 2017
Engineering of a 3′-sulpho-Galβ1-4GlcNAc-specific probe by a single amino acid substitution of a fungal galectin journal March 2015
Display of the human mucinome with defined O-glycans by gene engineered cells journal July 2021
MUSCLE: multiple sequence alignment with high accuracy and high throughput journal March 2004
Geneious Basic: An integrated and extendable desktop software platform for the organization and analysis of sequence data journal April 2012
ProtTest: selection of best-fit models of protein evolution journal January 2005
MrBayes 3.2: Efficient Bayesian Phylogenetic Inference and Model Choice Across a Large Model Space journal February 2012
Phaser crystallographic software journal July 2007
PHENIX: a comprehensive Python-based system for macromolecular structure solution journal January 2010
Coot model-building tools for molecular graphics journal November 2004
Comparison of simple potential functions for simulating liquid water journal July 1983
ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB journal July 2015
The Amber biomolecular simulation programs journal January 2005
Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes journal March 1977
PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data journal June 2013