Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

TRIM5[alpha] Restriction of HIV-1-N74D Viruses in Lymphocytes Is Caused by a Loss of Cyclophilin A P

Journal Article · · Viruses-Basel
DOI:https://doi.org/10.3390/v14020363· OSTI ID:1872614

Research Organization:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
DOE - Office Of Science; National Institutes of Health (NIH)
OSTI ID:
1872614
Journal Information:
Viruses-Basel, Vol. 14, Issue (2)
Country of Publication:
United States
Language:
ENGLISH

References (38)

Flexible Use of Nuclear Import Pathways by HIV-1 journal March 2010
Human Cytosolic Extracts Stabilize the HIV-1 Core journal July 2013
TNPO3 protects HIV-1 replication from CPSF6-mediated capsid stabilization in the host cell cytoplasm journal February 2013
Structural basis of HIV-1 capsid recognition by PF74 and CPSF6 journal December 2014
The ability of TNPO3-depleted cells to inhibit HIV-1 infection requires CPSF6 journal January 2013
TRIM34 restricts HIV-1 and SIV capsids in a TRIM5α-dependent manner journal April 2020
Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Nondividing Cells journal October 2018
A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin journal February 2016
The Cleavage and Polyadenylation Specificity Factor 6 (CPSF6) Subunit of the Capsid-recruited Pre-messenger RNA Cleavage Factor I (CFIm) Complex Mediates HIV-1 Integration into Genes journal May 2016
Direct Visualization of HIV-1 Replication Intermediates Shows that Capsid and CPSF6 Modulate HIV-1 Intra-nuclear Invasion and Integration journal November 2015
Human Immunodeficiency Virus Type 1 Capsid Mutation N74D Alters Cyclophilin A Dependence and Impairs Macrophage Infection journal February 2012
HIV-1 evades innate immune recognition through specific cofactor recruitment journal November 2013
In Vivo Functions of CPSF6 for HIV-1 as Revealed by HIV-1 Capsid Evolution in HLA-B27-Positive Subjects journal January 2014
Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core journal March 2020
Cyclophilin A protects HIV-1 from restriction by human TRIM5α journal October 2019
MxB binds to the HIV-1 core and prevents the uncoating process of HIV-1 journal August 2014
A human TRIM5α B30.2/SPRY domain mutant gains the ability to restrict and prematurely uncoat B-tropic murine leukemia virus journal September 2008
Binding of host factors to stabilized HIV-1 capsid tubes journal October 2018
A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells journal October 2016
CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions journal December 2018
Kinetic Analysis of the Role of Intersubunit Interactions in Human Immunodeficiency Virus Type 1 Capsid Protein Assembly In Vitro journal July 2002
X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability journal June 2015
Integration, scaling, space-group assignment and post-refinement journal January 2010
Solving structures of protein complexes by molecular replacement with Phaser journal December 2006
Phaser crystallographic software journal July 2007
REFMAC 5 for the refinement of macromolecular crystal structures journal March 2011
XDS journal January 2010
Features and development of Coot journal March 2010
Coot model-building tools for molecular graphics journal November 2004
MolProbity: More and better reference data for improved all-atom structure validation: PROTEIN SCIENCE.ORG journal November 2017
Comparative requirements for the restriction of retrovirus infection by TRIM5α and TRIMCyp journal December 2007
Requirements for capsid-binding and an effector function in TRIMCyp-mediated restriction of HIV-1 journal August 2006
BI-2 destabilizes HIV-1 cores during infection and Prevents Binding of CPSF6 to the HIV-1 Capsid journal December 2014
GS-CA1 and lenacapavir stabilize the HIV-1 core and modulate the core interaction with cellular factors journal January 2022
A B-Box 2 Surface Patch Important for TRIM5α Self-Association, Capsid Binding Avidity, and Retrovirus Restriction journal August 2009
Hexagonal assembly of a restricting TRIM5  protein journal December 2010
Determinants of the Higher Order Association of the Restriction Factor TRIM5α and Other Tripartite Motif (TRIM) Proteins journal August 2011
Caging the Beast: TRIM5α Binding to the HIV-1 Core journal April 2011

Similar Records

TRIM5[alpha] Restriction of HIV-1-N74D Viruses in Lymphocytes Is Caused by a Loss of Cyclophilin A P
Journal Article · 2022 · Viruses-Basel · OSTI ID:1871705

Structural Insight into HIV-1 Capsid Recognition by Rhesus TRIM5 alpha
Journal Article · 2012 · Proceedings of the National Academy of Sciences of the USA · OSTI ID:1162909

Structural insight into HIV-1 capsid recognition by rhesus TRIM5[alpha]
Journal Article · 2012 · Proc. Natl. Acad. Sci. USA · OSTI ID:1054797

Related Subjects