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Identification of Endoplasmic Reticulum [alpha]-Glucosidase I from a Thermophilic Fungus as a Platfo

Journal Article · · Biochemistry-US
; ; ;
Research Organization:
Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)
Sponsoring Organization:
DOE - Office Of Science; UNIVERSITY
OSTI ID:
1872605
Journal Information:
Biochemistry-US, Journal Name: Biochemistry-US Journal Issue: (10) Vol. 61
Country of Publication:
United States
Language:
ENGLISH

References (43)

Targeting Endoplasmic Reticulum α-Glucosidase I with a Single-Dose Iminosugar Treatment Protects against Lethal Influenza and Dengue Virus Infections journal March 2020
Antiviral therapies targeting host ER alpha-glucosidases: Current status and future directions journal September 2013
Specificity of Processing α-Glucosidase I Is Guided by the Substrate Conformation journal May 2013
Synthesis and Biological Characterisation of Novel N -Alkyl-Deoxynojirimycin α-Glucosidase Inhibitors journal April 2009
Medicinal chemistry strategies toward host targeting antiviral agents journal February 2020
Identifying protein construct variants with increased crystallization propensity--A case study journal December 2006
Synthesis of α-d-Glcp-(1 → 2)-α-d-Glcp-(1 → 3)-α-d-Glcp-O-(CH2)8COOCH3 for use in the assay of α-glucosidase I activity journal December 1996
Features and development of Coot journal March 2010
Consistent mutational paths predict eukaryotic thermostability journal January 2013
New pharmacological strategies to fight enveloped viruses journal September 2014
Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4 journal May 2016
Baloxavir and Treatment-Emergent Resistance: Public Health Insights and Next Steps journal July 2019
The Use of Calnexin and Calreticulin by Cellular and Viral Glycoproteins journal August 2005
Role of N-linked oligosaccharide recognition, glucose trimming, and calnexin in glycoprotein folding and quality control. journal February 1994
Glucosidase I, a transmembrane endoplasmic reticular glycoprotein with a luminal catalytic domain. journal September 1991
UDP-GlC:glycoprotein glucosyltransferase-glucosidase II, the ying-yang of the ER quality control journal July 2010
Phaser crystallographic software journal July 2007
Protein stability: a crystallographer's perspective journal January 2016
REFMAC 5 for the refinement of macromolecular crystal structures journal March 2011
Structure of a β1-adrenergic G-protein-coupled receptor journal June 2008
An Evolutionarily Conserved Structural Platform for PRC2 Inhibition by a Class of Ezh2 Inhibitors journal June 2018
Imino Sugars That are Less Toxic but More Potent as Antivirals, In Vitro , Compared with N-n-Nonyl DNJ journal October 2002
Protein and DNA Sequence Determinants of Thermophilic Adaptation journal January 2007
Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix journal October 2019
Dengue Virus Evolution under a Host-Targeted Antiviral journal May 2015
Lack of selective resistance of influenza A virus in presence of host-targeted antiviral, UV-4B journal May 2019
Emerging Principles for the Therapeutic Exploitation of Glycosylation journal January 2014
Glycosylation, Hypogammaglobulinemia, and Resistance to Viral Infections journal April 2014
N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum α-Glucosidases I and II with Antiviral Activity journal December 2021
[20] Processing of X-ray diffraction data collected in oscillation mode book January 1997
Structures of mammalian ER α-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals journal July 2016
Engineering Archeal Surrogate Systems for the Development of Protein–Protein Interaction Inhibitors against Human RAD51 journal November 2016
PHENIX: a comprehensive Python-based system for macromolecular structure solution journal January 2010
An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum journal November 2014
An iminosugar with potent inhibition of dengue virus infection in vivo journal April 2013
The iminosugars celgosivir, castanospermine and UV-4 inhibit SARS-CoV-2 replication journal September 2020
A versatile ligation-independent cloning method suitable for high-throughput expression screening applications journal March 2007
Structural basis for two-step glucose trimming by glucosidase II involved in ER glycoprotein quality control journal February 2016
Antiviral drug discovery: broad-spectrum drugs from nature journal January 2015
Molecular basis for the bifunctional Uba4–Urm1 sulfur‐relay system in tRNA thiolation and ubiquitin‐like conjugation journal September 2020
Synthesis, in vitro inhibitory activity, kinetic study and molecular docking of novel N -alkyl–deoxynojirimycin derivatives as potential α-glucosidase inhibitors journal January 2020
Iminosugars: A host-targeted approach to combat Flaviviridae infections journal December 2020
N -glycan processing in ER quality control journal November 2006

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