Human CEACAM1 N-domain dimerization is independent from glycan modifications

Dufrisne, Meagan Belcher; Swope, Nicole; Kieber, Marissa; Yang, Jeong-Yeh; Han, Ji; Li, Jason; Moremen, Kelley W.; Prestegard, James H.; Columbus, Linda

doi:10.1016/j.str.2022.02.003

Human CEACAM1 N-domain dimerization is independent from glycan modifications

Journal Article · 01 May 2022 · Structure

DOI:https://doi.org/10.1016/j.str.2022.02.003· OSTI ID:1872595

Dufrisne, Meagan Belcher; Swope, Nicole; Kieber, Marissa; Yang, Jeong-Yeh; Han, Ji; Li, Jason; Moremen, Kelley W.; Prestegard, James H.; Columbus, Linda

Research Organization:: Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)

Sponsoring Organization:: DOE - Office Of Science; NIH

OSTI ID:: 1872595

Journal Information:: Structure, Journal Name: Structure Journal Issue: (5) Vol. 30

Country of Publication:: United States

Language:: ENGLISH

References (60)

A structural dissection of large protein-protein crystal packing contacts Luo, Jiesi; Liu, Zhongyu; Guo, Yanzhi Scientific Reports, Vol. 5, Issue 1 https://doi.org/10.1038/srep14214	journal	September 2015
Neisserial Opa Protein–CEACAM Interactions: Competition for Receptors as a Means of Bacterial Invasion and Pathogenesis Martin, Jennifer N.; Ball, Louise M.; Solomon, Tsega L. Biochemistry, Vol. 55, Issue 31 https://doi.org/10.1021/acs.biochem.6b00124	journal	August 2016
The Xplor-NIH NMR molecular structure determination package Schwieters, Charles D.; Kuszewski, John J.; Tjandra, Nico Journal of Magnetic Resonance, Vol. 160, Issue 1 https://doi.org/10.1016/S1090-7807(02)00014-9	journal	January 2003
Mammalian glycosylation in immunity Marth, Jamey D.; Grewal, Prabhjit K. Nature Reviews Immunology, Vol. 8, Issue 11 https://doi.org/10.1038/nri2417	journal	November 2008
Protein structural dynamics revealed by site-directed spin labeling and multifrequency EPR Nesmelov, Yuri E.; Thomas, David D. Biophysical Reviews, Vol. 2, Issue 2 https://doi.org/10.1007/s12551-010-0032-5	journal	April 2010
Expresso: automatic incorporation of structural information in multiple sequence alignments using 3D-Coffee Armougom, F.; Moretti, S.; Poirot, O. Nucleic Acids Research, Vol. 34, Issue Web Server https://doi.org/10.1093/nar/gkl092	journal	July 2006
Features and development of Coot Emsley, P.; Lohkamp, B.; Scott, W. G. Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 4 https://doi.org/10.1107/S0907444910007493	journal	March 2010
Human germline and pan-cancer variomes and their distinct functional profiles Pan, Yang; Karagiannis, Konstantinos; Zhang, Haichen Nucleic Acids Research, Vol. 42, Issue 18 https://doi.org/10.1093/nar/gku772	journal	September 2014
Integration, scaling, space-group assignment and post-refinement Kabsch, Wolfgang Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 2, p. 133-144 https://doi.org/10.1107/S0907444909047374	journal	January 2010
The Helicobacter pylori adhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA Bonsor, Daniel A.; Zhao, Qing; Schmidinger, Barbara The EMBO Journal, Vol. 37, Issue 13 https://doi.org/10.15252/embj.201798664	journal	May 2018
DEER Distance Measurements on Proteins Jeschke, Gunnar Annual Review of Physical Chemistry, Vol. 63, Issue 1 https://doi.org/10.1146/annurev-physchem-032511-143716	journal	May 2012
PHENIX: a comprehensive Python-based system for macromolecular structure solution Adams, Paul D.; Afonine, Pavel V.; Bunkóczi, Gábor Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 2, p. 213-221 https://doi.org/10.1107/S0907444909052925	journal	January 2010
MOLMOL: A program for display and analysis of macromolecular structures Koradi, Reto; Billeter, Martin; Wüthrich, Kurt Journal of Molecular Graphics, Vol. 14, Issue 1 https://doi.org/10.1016/0263-7855(96)00009-4	journal	February 1996
Helicobacter pylori adhesin HopQ disrupts trans dimerization in human CEACAM s Moonens, Kristof; Hamway, Youssef; Neddermann, Matthias The EMBO Journal, Vol. 37, Issue 13 https://doi.org/10.15252/embj.201798665	journal	June 2018
Learning generative models for protein fold families Balakrishnan, Sivaraman; Kamisetty, Hetunandan; Carbonell, Jaime G. Proteins: Structure, Function, and Bioinformatics, Vol. 79, Issue 4 https://doi.org/10.1002/prot.22934	journal	January 2011
Identifying conformational changes with site-directed spin labeling Hubbell, Wayne L.; Cafiso, David S.; Altenbach, Christian Nature Structural Biology, Vol. 7, Issue 9, p. 735-739 https://doi.org/10.1038/78956	journal	September 2000
Distance measurements on spin-labelled biomacromolecules by pulsed electron paramagnetic resonance Jeschke, Gunnar; Polyhach, Yevhen Physical Chemistry Chemical Physics, Vol. 9, Issue 16 https://doi.org/10.1039/b614920k	journal	January 2007
A framework for organizing cancer-related variations from existing databases, publications and NGS data using a High-performance Integrated Virtual Environment (HIVE) Wu, Tsung-Jung; Shamsaddini, Amirhossein; Pan, Yang Database, Vol. 2014 https://doi.org/10.1093/database/bau022	journal	January 2014
Inside-out Signaling Promotes Dynamic Changes in the Carcinoembryonic Antigen-related Cellular Adhesion Molecule 1 (CEACAM1) Oligomeric State to Control Its Cell Adhesion Properties Patel, Prerna C.; Lee, Hannah S. W.; Ming, Aaron Y. K. Journal of Biological Chemistry, Vol. 288, Issue 41 https://doi.org/10.1074/jbc.M113.504639	journal	September 2013
Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis Beauchemin, Nicole; Arabzadeh, Azadeh Cancer and Metastasis Reviews, Vol. 32, Issue 3-4 https://doi.org/10.1007/s10555-013-9444-6	journal	August 2013
Enzymatic Basis for N -Glycan Sialylation : STRUCTURE OF RAT α2,6-SIALYLTRANSFERASE (ST6GAL1) REVEALS CONSERVED AND UNIQUE FEATURES FOR GLYCAN SIALYLATION Meng, Lu; Forouhar, Farhad; Thieker, David Journal of Biological Chemistry, Vol. 288, Issue 48 https://doi.org/10.1074/jbc.M113.519041	journal	October 2013
Phaser crystallographic software McCoy, Airlie J.; Grosse-Kunstleve, Ralf W.; Adams, Paul D. Journal of Applied Crystallography, Vol. 40, Issue 4 https://doi.org/10.1107/S0021889807021206	journal	July 2007
Crystal structure of murine sCEACAM1a[1,4]: a coronavirus receptor in the CEA family Tan, K. The EMBO Journal, Vol. 21, Issue 9 https://doi.org/10.1093/emboj/21.9.2076	journal	May 2002
Signaling by epithelial members of the CEACAM family – mucosal docking sites for pathogenic bacteria Tchoupa, Arnaud; Schuhmacher, Tamara; Hauck, Christof R. Cell Communication and Signaling, Vol. 12, Issue 1 https://doi.org/10.1186/1478-811X-12-27	journal	January 2014
Structure and function in rhodopsin: High-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line Reeves, P. J.; Callewaert, N.; Contreras, R. Proceedings of the National Academy of Sciences, Vol. 99, Issue 21 https://doi.org/10.1073/pnas.212519299	journal	October 2002
Structural and Molecular Evidence Suggesting Coronavirus-driven Evolution of Mouse Receptor Peng, Guiqing; Yang, Yang; Pasquarella, Joseph R. Journal of Biological Chemistry, Vol. 292, Issue 6 https://doi.org/10.1074/jbc.M116.764266	journal	February 2017
Glycosylation Alters Dimerization Properties of a Cell-surface Signaling Protein, Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 (CEACAM1) Zhuo, You; Yang, Jeong-Yeh; Moremen, Kelley W. Journal of Biological Chemistry, Vol. 291, Issue 38 https://doi.org/10.1074/jbc.M116.740050	journal	September 2016
Homophilic adhesion of human CEACAM1 involves N-terminal domain interactions: structural analysis of the binding site Watt, S. M. Blood, Vol. 98, Issue 5 https://doi.org/10.1182/blood.V98.5.1469	journal	September 2001
The N‐domain of the human CD66a adhesion molecule is a target for Opa proteins of Neisseria meningitidis and Neisseria gonorrhoeae Virji, Mumtaz; Watt, Suzanne M.; Barker, Stephanie Molecular Microbiology, Vol. 22, Issue 5 https://doi.org/10.1046/j.1365-2958.1996.01548.x	journal	December 1996
The CEACAM1 N-terminal Ig domain mediates cis- and trans-binding and is essential for allosteric rearrangements of CEACAM1 microclusters Klaile, Esther; Vorontsova, Olga; Sigmundsson, Kristmundur Journal of Cell Biology, Vol. 187, Issue 4 https://doi.org/10.1083/jcb.200904149	journal	November 2009
CEACAM1 regulates TIM-3-mediated tolerance and exhaustion Huang, Yu-Hwa; Zhu, Chen; Kondo, Yasuyuki Nature, Vol. 517, Issue 7534 https://doi.org/10.1038/nature13848	journal	October 2014
Osmolyte perturbation reveals conformational equilibria in spin-labeled proteins López, Carlos J.; Fleissner, Mark R.; Guo, Zhefeng Protein Science, Vol. 18, Issue 8 https://doi.org/10.1002/pro.180	journal	August 2009
Diverse oligomeric states of CEACAM IgV domains Bonsor, Daniel A.; Günther, Sebastian; Beadenkopf, Robert Proceedings of the National Academy of Sciences, Vol. 112, Issue 44 https://doi.org/10.1073/pnas.1509511112	journal	October 2015
CEA adhesion molecules: multifunctional proteins with signal-regulatory properties Öbrink, Björn Current Opinion in Cell Biology, Vol. 9, Issue 5 https://doi.org/10.1016/S0955-0674(97)80114-7	journal	October 1997
Rotamer libraries of spin labelled cysteines for protein studies Polyhach, Yevhen; Bordignon, Enrica; Jeschke, Gunnar Phys. Chem. Chem. Phys., Vol. 13, Issue 6 https://doi.org/10.1039/C0CP01865A	journal	January 2011
A Subfamily of Dr Adhesins of Escherichia coli Bind Independently to Decay-accelerating Factor and the N-domain of Carcinoembryonic Antigen Korotkova, Natalia; Cota, Ernesto; Lebedin, Yuri Journal of Biological Chemistry, Vol. 281, Issue 39 https://doi.org/10.1074/jbc.M605681200	journal	August 2006
Self Recognition in the Ig Superfamily Taheri, Maryam; Saragovi, Uri; Fuks, Abraham Journal of Biological Chemistry, Vol. 275, Issue 35 https://doi.org/10.1016/S0021-9258(19)61463-8	journal	September 2000
A new spin on protein dynamics Columbus, Linda; Hubbell, Wayne L. Trends in Biochemical Sciences, Vol. 27, Issue 6 https://doi.org/10.1016/S0968-0004(02)02095-9	journal	June 2002
BioMuta and BioXpress: mutation and expression knowledgebases for cancer biomarker discovery Dingerdissen, Hayley M.; Torcivia-Rodriguez, John; Hu, Yu Nucleic Acids Research, Vol. 46, Issue D1 https://doi.org/10.1093/nar/gkx907	journal	October 2017
Origins of coevolution between residues distant in protein 3D structures Anishchenko, Ivan; Ovchinnikov, Sergey; Kamisetty, Hetunandan Proceedings of the National Academy of Sciences, Vol. 114, Issue 34 https://doi.org/10.1073/pnas.1702664114	journal	August 2017
Site-specific incorporation of biophysical probes into proteins. Cornish, V. W.; Benson, D. R.; Altenbach, C. A. Proceedings of the National Academy of Sciences, Vol. 91, Issue 8 https://doi.org/10.1073/pnas.91.8.2910	journal	April 1994
Binding of Dr adhesins of Escherichia coli to carcinoembryonic antigen triggers receptor dissociation: Dr adhesins trigger CEA dimer dissociation Korotkova, Natalia; Yang, Yi; Le Trong, Isolde Molecular Microbiology, Vol. 67, Issue 2 https://doi.org/10.1111/j.1365-2958.2007.06054.x	journal	December 2007
Deciphering key features in protein structures with the new ENDscript server Robert, Xavier; Gouet, Patrice Nucleic Acids Research, Vol. 42, Issue W1 https://doi.org/10.1093/nar/gku316	journal	April 2014
Correction: Glycosylation alters dimerization properties of a cell-surface signaling protein, carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1). Zhuo, You; Yang, Jeong-Yeh; Moremen, Kelley W. Journal of Biological Chemistry, Vol. 295, Issue 11 https://doi.org/10.1074/jbc.AAC120.013039	journal	March 2020
Assessing the utility of coevolution-based residue-residue contact predictions in a sequence- and structure-rich era Kamisetty, H.; Ovchinnikov, S.; Baker, D. Proceedings of the National Academy of Sciences, Vol. 110, Issue 39 https://doi.org/10.1073/pnas.1314045110	journal	September 2013
How good are my data and what is the resolution? Evans, Philip R.; Murshudov, Garib N. Acta Crystallographica Section D Biological Crystallography, Vol. 69, Issue 7 https://doi.org/10.1107/S0907444913000061	journal	June 2013
Structure of the N-terminal dimerization domain of CEACAM7 Bonsor, Daniel A.; Beckett, Dorothy; Sundberg, Eric J. Acta Crystallographica Section F Structural Biology Communications, Vol. 71, Issue 9, p. 1169-1175 https://doi.org/10.1107/S2053230X15013576	journal	August 2015
Structure of the N-terminal domain of human CEACAM1: binding target of the opacity proteins during invasion of Neisseria meningitidis and N. gonorrhoeae Fedarovich, Alena; Tomberg, Joshua; Nicholas, Robert A. Acta Crystallographica Section D Biological Crystallography, Vol. 62, Issue 9 https://doi.org/10.1107/S0907444906020737	journal	August 2006
A Dynamic Protein–Protein Coupling between the TonB-Dependent Transporter FhuA and TonB Sarver, Jessica L.; Zhang, Michael; Liu, Lishan Biochemistry, Vol. 57, Issue 6 https://doi.org/10.1021/acs.biochem.7b01223	journal	January 2018
Critical determinants of host receptor targeting by Neisseria meningitidis and Neisseria gonorrhoeae : identification of Opa adhesiotopes on the N-domain of CD66 molecules Virji, Mumtaz; Evans, Debbie; Hadfield, Andrea Molecular Microbiology, Vol. 34, Issue 3 https://doi.org/10.1046/j.1365-2958.1999.01620.x	journal	November 1999
Paramagnetic Tag for Glycosylation Sites in Glycoproteins: Structural Constraints on Heparan Sulfate Binding to Robo1 Moure, Maria J.; Eletsky, Alexander; Gao, Qi ACS Chemical Biology, Vol. 13, Issue 9 https://doi.org/10.1021/acschembio.8b00511	journal	July 2018
Dead-Time Free Measurement of Dipole–Dipole Interactions between Electron Spins Pannier, M.; Veit, S.; Godt, A. Journal of Magnetic Resonance, Vol. 142, Issue 2 https://doi.org/10.1006/jmre.1999.1944	journal	February 2000
Motion of Spin-Labeled Side Chains in T4 Lysozyme. Correlation with Protein Structure and Dynamics ^† Mchaourab, Hassane S.; Lietzow, Michael A.; Hideg, Kalman Biochemistry, Vol. 35, Issue 24 https://doi.org/10.1021/bi960482k	journal	January 1996
CEACAMs: their role in physiology and pathophysiology Kuespert, Katharina; Pils, Stefan; Hauck, Christof R. Current Opinion in Cell Biology, Vol. 18, Issue 5 https://doi.org/10.1016/j.ceb.2006.08.008	journal	October 2006
Expression system for structural and functional studies of human glycosylation enzymes Moremen, Kelley W.; Ramiah, Annapoorani; Stuart, Melissa Nature Chemical Biology, Vol. 14, Issue 2 https://doi.org/10.1038/nchembio.2539	journal	December 2017
The Transmembrane Domain of CEACAM1-4S Is a Determinant of Anchorage Independent Growth and Tumorigenicity Lawson, Erica L.; Mills, David R.; Brilliant, Kate E. PLoS ONE, Vol. 7, Issue 1 https://doi.org/10.1371/journal.pone.0029606	journal	January 2012
Coevolution of activating and inhibitory receptors within mammalian carcinoembryonic antigen families Kammerer, Robert; Zimmermann, Wolfgang BMC Biology, Vol. 8, Issue 1 https://doi.org/10.1186/1741-7007-8-12	journal	February 2010
Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium Gandhi, Amit K.; Sun, Zhen-Yu J.; Kim, Walter M. Communications Biology, Vol. 4, Issue 1 https://doi.org/10.1038/s42003-021-01871-2	journal	March 2021
The Critical Role of Residues ⁴³ R and ⁴⁴ Q of Carcinoembryonic Antigen Cell Adhesion Molecules-1 in the Protection from Killing by Human NK Cells Markel, Gal; Gruda, Raizy; Achdout, Hagit The Journal of Immunology, Vol. 173, Issue 6 https://doi.org/10.4049/jimmunol.173.6.3732	journal	September 2004
DeerAnalysis2006—a comprehensive software package for analyzing pulsed ELDOR data Jeschke, G.; Chechik, V.; Ionita, P. Applied Magnetic Resonance, Vol. 30, Issue 3-4 https://doi.org/10.1007/BF03166213	journal	June 2006

Similar Records

Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium

Journal Article · 2021 · Commun. Biol. · OSTI ID:1783834

Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium

Journal Article · 2021 · Communications Biology · OSTI ID:1783763

Structure of the N-terminal domain of human CEACAM1: binding target of the opacity proteins during invasion of Neisseria miningitidis and N. gonorrhoeae

Journal Article · 2015 · Acta Crystallogr. D · OSTI ID:1170433

Human CEACAM1 N-domain dimerization is independent from glycan modifications

Citation Formats

References (60)

Similar Records

Related Subjects