Discovery of Dual TAF1-ATR Inhibitors and Ligand-Induced Structural Changes of the TAF1 Tandem Bromo

Karim, Rezaul Md; Yang, Leixiang; Chen, Lihong; Bikowitz, Melissa J.; Lu, Junhao; Grassie, Dylan; Shultz, Zachary P.; Lopchuk, Justin M.; Chen, Jiandong; Schonbrunn, Ernst

doi:10.1021/acs.jmedchem.1c01999

Discovery of Dual TAF1-ATR Inhibitors and Ligand-Induced Structural Changes of the TAF1 Tandem Bromo

Journal Article · 31 January 2022 · J. Med. Chem.

DOI:https://doi.org/10.1021/acs.jmedchem.1c01999· OSTI ID:1871740

Karim, Rezaul Md; Yang, Leixiang; Chen, Lihong; Bikowitz, Melissa J.; Lu, Junhao; Grassie, Dylan; Shultz, Zachary P.; Lopchuk, Justin M.; Chen, Jiandong; Schonbrunn, Ernst

Research Organization:: Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)

Sponsoring Organization:: DOE - Office Of Science; INDUSTRY

OSTI ID:: 1871740

Journal Information:: J. Med. Chem., Journal Name: J. Med. Chem. Journal Issue: (5) Vol. 65

Country of Publication:: United States

Language:: ENGLISH

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