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Interactions of Protein Kinase C-α C1A and C1B Domains with Membranes: A Combined Computational and Experimental Study
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journal
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August 2014 |
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Synthesis and evaluation of designed PKC modulators for enhanced cancer immunotherapy
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journal
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April 2020 |
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Bryostatin 1 Promotes Synaptogenesis and Reduces Dendritic Spine Density in Cortical Cultures through a PKC-Dependent Mechanism
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journal
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May 2020 |
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A Simple Analogue of Tumor-Promoting Aplysiatoxin Is an Antineoplastic Agent Rather Than a Tumor Promoter: Development of a Synthetically Accessible Protein Kinase C Activator with Bryostatin-like Activity
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journal
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May 2009 |
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Myotonic dystrophy kinase-related Cdc42-binding kinases (MRCK), the ROCK-like effectors of Cdc42 and Rac1
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journal
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April 2015 |
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Diacylglycerol, when simplicity becomes complex
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journal
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January 2007 |
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Identification of the activator-binding residues in the second cysteine-rich regulatory domain of protein kinase Cθ (PKCθ)
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journal
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March 2013 |
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Taxonomy and function of C1 protein kinase C homology domains: C1 domains
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journal
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February 1997 |
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Toggling of Diacylglycerol Affinity Correlates with Conformational Plasticity in C1 Domains
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journal
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May 2017 |
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Scaling and assessment of data quality
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journal
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December 2005 |
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Efficacy and safety of ingenol mebutate gel in field treatment of actinic keratosis on full face, balding scalp, or approximately 250 cm2 on the chest: A phase 3 randomized controlled trial
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journal
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March 2020 |
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NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy
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journal
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December 2014 |
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Differential irreversible insertion of protein kinase C into phospholipid vesicles by phorbol esters and related activators.
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journal
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October 1992 |
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1H, 13C and 15N NMR assignments of the C1A and C1B subdomains of PKC-delta
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journal
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December 2010 |
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A method for efficient isotopic labeling of recombinant proteins
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journal
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May 2001 |
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RasGRP, a Ras Guanyl Nucleotide- Releasing Protein with Calcium- and Diacylglycerol-Binding Motifs
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journal
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May 1998 |
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Role of protein kinase C activation in oocyte maturation and steroidogenesis in ovarian follicles ofRana pipiens: Studies with phorbol 12-myristate 13-acetate
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journal
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November 1988 |
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Crystal structure of the Cys2 activator-binding domain of protein kinase Cδ in complex with phorbol ester
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journal
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June 1995 |
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Single-Molecule Studies Reveal a Hidden Key Step in the Activation Mechanism of Membrane-Bound Protein Kinase C-α
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journal
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March 2014 |
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A Single Residue in the C1 Domain Sensitizes Novel Protein Kinase C Isoforms to Cellular Diacylglycerol Production
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journal
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January 2007 |
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JLigand : a graphical tool for the CCP 4 template-restraint library
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journal
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March 2012 |
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Synthetic Ingenols Maximize Protein Kinase C-Induced HIV-1 Latency Reversal
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journal
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November 2018 |
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Multi-stage chemical carcinogenesis in mouse skin: Fundamentals and applications
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journal
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August 2009 |
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Diacylglycerol kinases: Relationship to other lipid kinases
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journal
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January 2019 |
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PKC and the control of localized signal dynamics
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journal
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February 2010 |
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Practical Synthesis of Prostratin, DPP, and Their Analogs, Adjuvant Leads Against Latent HIV
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journal
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May 2008 |
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Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN
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journal
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February 2017 |
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Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
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journal
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October 2019 |
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The colorimetric determination of phosphorus
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journal
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January 1932 |
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Probing the Determinants of Diacylglycerol Binding Affinity in the C1B Domain of Protein Kinase Cα
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journal
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May 2011 |
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Differential Binding Modes of Diacylglycerol (DAG) and DAG Lactones to Protein Kinase C (PK-C)
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journal
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March 2003 |
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Molecular dynamics simulations reveal ligand-controlled positioning of a peripheral protein complex in membranes
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journal
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February 2017 |
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NMRPipe: A multidimensional spectral processing system based on UNIX pipes
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journal
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November 1995 |
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Coot model-building tools for molecular graphics
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journal
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November 2004 |
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Interfacial Partitioning of a Loop Hinge Residue Contributes to Diacylglycerol Affinity of Conserved Region 1 Domains
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journal
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October 2014 |
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Structural insights into C1-ligand interactions: Filling the gaps by in silico methods
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journal
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January 2021 |
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UCSF Chimera?A visualization system for exploratory research and analysis
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journal
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January 2004 |
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Coordinated activation of the Rac-GAP β2-chimaerin by an atypical proline-rich domain and diacylglycerol
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journal
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May 2013 |
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XDS
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journal
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January 2010 |
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Protein Kinase C Translocation by Modified Phorbol Esters with Functionalized Lipophilic Regions
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journal
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May 2003 |
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Polder maps: improving OMIT maps by excluding bulk solvent
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journal
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February 2017 |
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LigPlot+: Multiple Ligand–Protein Interaction Diagrams for Drug Discovery
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journal
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October 2011 |
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How good are my data and what is the resolution?
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journal
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June 2013 |
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Partial Metal Ion Saturation of C2 Domains Primes Synaptotagmin 1-Membrane Interactions
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journal
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March 2020 |
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Conformationally Constrained Analogues of Diacylglycerol (DAG). 28. DAG-dioxolanones Reveal a New Additional Interaction Site in the C1b Domain of PKCδ
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journal
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June 2007 |
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Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.
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journal
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July 1982 |
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Ensemble Approach for NMR Structure Refinement against 1 H Paramagnetic Relaxation Enhancement Data Arising from a Flexible Paramagnetic Group Attached to a Macromolecule
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journal
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May 2004 |
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Residues in the Second Cysteine-rich Region of Protein Kinase C δ Relevant to Phorbol Ester Binding as Revealed by Site-directed Mutagenesis
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journal
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September 1995 |
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Characterization of phorbol esters activity on individual mammalian protein kinase C isoforms, using the yeast phenotypic assay
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journal
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May 2004 |
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Forcing an enemy into the open
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journal
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August 2012 |
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electronic Ligand Builder and Optimization Workbench ( eLBOW ): a tool for ligand coordinate and restraint generation
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journal
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September 2009 |
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Intramolecular Conformational Changes Optimize Protein Kinase C Signaling
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journal
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April 2014 |
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Characterization of AJH-836, a diacylglycerol-lactone with selectivity for novel PKC isozymes
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journal
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June 2018 |
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Dynamics and Membrane Interactions of Protein Kinase C
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journal
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August 2015 |
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Prodrugs of PKC modulators show enhanced HIV latency reversal and an expanded therapeutic window
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journal
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May 2020 |
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High-Resolution NMR Spectroscopy: An Alternative Fast Tool for Qualitative and Quantitative Analysis of Diacylglycerol (DAG) Oil
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journal
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May 2011 |