Discovery of Potent Orally Bioavailable WD Repeat Domain 5 (WDR5) Inhibitors Using a Pharmacophore-B

Teuscher, Kevin B.; Meyers, Kenneth M.; Wei, Qiangqiang; Mills, Jonathan J.; Tian, Jianhua; Alvarado, Joseph; Sai, Jiqing; Van Meveren, Mayme; South, Taylor M.; Rietz, Tyson A.; Zhao, Bin; Moore, William J.; Stott, Gordon M.; Tansey, William P.; Lee, Taekyu; Fesik, Stephen W.

doi:10.1021/acs.jmedchem.2c00195

Discovery of Potent Orally Bioavailable WD Repeat Domain 5 (WDR5) Inhibitors Using a Pharmacophore-B

Journal Article · 01 April 2022 · J. Med. Chem.

DOI:https://doi.org/10.1021/acs.jmedchem.2c00195· OSTI ID:1866425

Teuscher, Kevin B.; Meyers, Kenneth M.; Wei, Qiangqiang; Mills, Jonathan J.; Tian, Jianhua; Alvarado, Joseph; Sai, Jiqing; Van Meveren, Mayme; South, Taylor M.; Rietz, Tyson A.; Zhao, Bin; Moore, William J.; Stott, Gordon M.; Tansey, William P.; Lee, Taekyu; Fesik, Stephen W.

Research Organization:: Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)

Sponsoring Organization:: DOE - Office Of Science; NCI; NIH

OSTI ID:: 1866425

Journal Information:: J. Med. Chem., Journal Name: J. Med. Chem. Journal Issue: (8) Vol. 65

Country of Publication:: United States

Language:: ENGLISH

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