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Title: Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed

Journal Article · · Eur. J. Med. Chem.

Research Organization:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
DOE - Office Of Science; FOREIGN
OSTI ID:
1863976
Journal Information:
Eur. J. Med. Chem., Vol. 234
Country of Publication:
United States
Language:
ENGLISH

References (27)

The Roles of Histone Deacetylases and Their Inhibitors in Cancer Therapy journal September 2020
HDAC2: a critical factor in health and disease journal December 2009
HDAC3 Activity is Essential for Human Leukemic Cell Growth and the Expression of β-catenin, MYC, and WT1 journal September 2019
c-Myc Modulation and Acetylation Is a Key HDAC Inhibitor Target in Cancer journal June 2016
Histone deacetylase 10 structure and molecular function as a polyamine deacetylase journal May 2017
Histone deacetylase 10 promotes autophagy-mediated cell survival journal June 2013
Polyamine Deacetylase Structure and Catalysis: Prokaryotic Acetylpolyamine Amidohydrolase and Eukaryotic HDAC10 journal March 2018
The interplay between DNA repair and autophagy in cancer therapy journal March 2015
Key Regulators of Autophagosome Closure journal October 2021
Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance journal July 2018
Histone deacetylase 10 knockout activates chaperone-mediated autophagy and accelerates the decomposition of its substrate journal February 2020
Phase II study of the histone deacetylase inhibitor MGCD0103 in patients with previously treated chronic lymphocytic leukaemia journal November 2009
Histone Deacetylase in Chronic Lymphocytic Leukemia journal January 2011
HDAC isoenzyme expression is deregulated in chronic lymphocytic leukemia B-cells and has a complex prognostic significance journal December 2012
HDAC10 deletion promotes Foxp3+ T-regulatory cell function journal January 2020
Structural Basis for the Selective Inhibition of HDAC10, the Cytosolic Polyamine Deacetylase journal July 2020
Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated journal April 2019
The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines journal June 2018
Discovery of a new class of histone deacetylase inhibitors with a novel zinc binding group journal January 2015
Prolonged tau clearance and stress vulnerability rescue by pharmacological activation of autophagy in tauopathy neurons journal June 2020
Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors journal March 2018
Loss of Wilms tumor 1 protein is a marker for apoptosis in response to replicative stress in leukemic cells journal March 2018
Design and biological evaluation of tetrahydro-β-carboline derivatives as highly potent histone deacetylase 6 (HDAC6) inhibitors journal May 2018
Design, synthesis, and biological evaluation of dual targeting inhibitors of histone deacetylase 6/8 and bromodomain BRPF1 journal August 2020
Design, Synthesis, and Biological Evaluation of 2-Aminobenzanilide Derivatives as Potent and Selective HDAC Inhibitors journal May 2012
Structural Basis for the Inhibition of Histone Deacetylase 8 (HDAC8), a Key Epigenetic Player in the Blood Fluke Schistosoma mansoni journal September 2013
Phaser crystallographic software journal July 2007

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