GROMACS: High performance molecular simulations through multi-level parallelism from laptops to supercomputers
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September 2015 |
PHENIX: a comprehensive Python-based system for macromolecular structure solution
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January 2010 |
Posttranslational Modifications of RAS Proteins
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January 2018 |
Conformational control of small GTPases by AMPylation
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March 2020 |
The tumor-suppressive small GTPase DiRas1 binds the noncanonical guanine nucleotide exchange factor SmgGDS and antagonizes SmgGDS interactions with oncogenic small GTPases.
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May 2016 |
The structural basis of the activation of Ras by Sos
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July 1998 |
Dexras1 is a homeostatic regulator of exercise-dependent proliferation and cell survival in the hippocampal neurogenic niche
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March 2018 |
The use of resonance energy transfer in high-throughput screening: BRET versus FRET
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August 2002 |
CHARMM: The biomolecular simulation program
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July 2009 |
Two Distinct Raf Domains Mediate Interaction with Ras
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April 1995 |
Allosteric modulation of Ras positions Q61 for a direct role in catalysis
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March 2010 |
RAS interaction with Sin1 is dispensable for mTORC2 assembly and activity
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August 2021 |
RAS Interaction with PI3K: More Than Just Another Effector Pathway
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March 2011 |
Dexras1 mediates glucocorticoid-associated adipogenesis and diet-induced obesity
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December 2013 |
Dexras1 Potentiates Photic and Suppresses Nonphotic Responses of the Circadian Clock
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September 2004 |
Regulation of Small GTPases by GEFs, GAPs, and GDIs
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January 2013 |
Probing the Structure and Mechanism of Ras Protein with an Expanded Genetic Code
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February 1993 |
Crystal Structure Reveals the Full Ras–Raf Interface and Advances Mechanistic Understanding of Raf Activation
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July 2021 |
Substitution of proline 82 by threonine induces autophosphorylating activity in GTP-binding domain of elongation factor Tu.
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April 1990 |
Database resources of the National Center for Biotechnology Information
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November 2015 |
PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion
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November 2015 |
Peptide Folding: When Simulation Meets Experiment
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January 1999 |
NMRPipe: A multidimensional spectral processing system based on UNIX pipes
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November 1995 |
RASSF effectors couple diverse RAS subfamily GTPases to the Hippo pathway
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October 2020 |
Structural basis of recognition of farnesylated and methylated KRAS4b by PDEδ
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October 2016 |
Structures of N-terminally processed KRAS provide insight into the role of N-acetylation
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July 2019 |
Ras signaling through RASSF proteins
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October 2016 |
Regulation of Raf-1 by Direct Feedback Phosphorylation
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January 2005 |
Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry
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February 2007 |
Coot model-building tools for molecular graphics
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November 2004 |
An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database
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November 1994 |
Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome
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August 2004 |
Multivalent assembly of KRAS with the RAS-binding and cysteine-rich domains of CRAF on the membrane
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May 2020 |
Allosteric Effects of the Oncogenic RasQ61L Mutant on Raf-RBD
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March 2015 |
Preparation and characterization of nucleotide-free and metal ion-free p21 “apoprotein”.
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June 1987 |
Crystal structure of Rnd3/RhoE: functional implications 1
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July 2002 |
Identification of a novel human Rho protein with unusual properties: GTPase deficiency and in vivo farnesylation
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June 1996 |
Guanine nucleotide binding properties of the mammalian RalA protein produced in Escherichia coli.
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April 1990 |
Effects of Raf Dimerization and Its Inhibition on Normal and Disease-Associated Raf Signaling
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February 2013 |
GTPase activity of Di-Ras proteins is stimulated by Rap1GAP proteins
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November 2010 |
Rhes influences striatal cAMP/PKA-dependent signaling and synaptic plasticity in a gender-sensitive fashion
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July 2015 |
Autophosphorylation of v-Ha-ras p21 is modulated by amino acid residue 12.
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May 1984 |
KRAS Alleles: The Devil Is in the Detail
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October 2017 |
Distinct requirements for Ras oncogenesis in human versus mouse cells
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August 2002 |
Methylation and proteolysis are essential for efficient membrane binding of prenylated p21K-ras(B).
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March 1991 |
Neurogenin 2 controls cortical neuron migration through regulation of Rnd2
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August 2008 |
Atypical KRAS G12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer
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October 2019 |
VMD: Visual molecular dynamics
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February 1996 |
In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C
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June 2014 |
CHARMM-GUI: A web-based graphical user interface for CHARMM
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March 2008 |
Biochemical properties of Ha-ras encoded p21 mutants and mechanism of the autophosphorylation reaction.
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August 1988 |
Expression, purification, crystallization and X-ray data collection for RAS and its mutants
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March 2016 |
Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D
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August 2019 |
Integration, scaling, space-group assignment and post-refinement
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January 2010 |
Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation
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January 2019 |
Dexamethasone Rapidly Induces a Novel Ras Superfamily Member-related Gene in AtT-20 Cells
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February 1998 |
Identification of a Novel Ras-Regulated Proapoptotic Pathway
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February 2002 |
New insight into the dynamic properties and the active site architecture of H-Ras p21 revealed by X-ray crystallography at very high resolution
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January 2010 |
Biochemical characterization of missense mutations in the Arf/Arl-family small GTPase Arl6 causing Bardet–Biedl syndrome
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April 2009 |
Di-Ras, a Distinct Subgroup of Ras Family GTPases with Unique Biochemical Properties
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October 2002 |
Touchdown PCR for increased specificity and sensitivity in PCR amplification
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August 2008 |
The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2
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February 2019 |
Three-dimensional structures of H-ras p21 mutants: Molecular basis for their inability to function as signal switch molecules
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August 1990 |
Biology of SNU Cell Lines
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January 2005 |
XRab40 and XCullin5 form a ubiquitin ligase complex essential for the noncanonical Wnt pathway
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July 2007 |
CHARMM-GUI Input Generator for NAMD, GROMACS, AMBER, OpenMM, and CHARMM/OpenMM Simulations Using the CHARMM36 Additive Force Field
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December 2015 |
Rab40b upregulation correlates with the prognosis of gastric cancer by promoting migration, invasion, and metastasis
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March 2015 |
The G protein signaling regulator RGS3 enhances the GTPase activity of KRAS
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October 2021 |
KRAS Switch Mutants D33E and A59G Crystallize in the State 1 Conformation
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December 2017 |
A RasGAP, DAB2IP, regulates lipid droplet homeostasis by serving as GAP toward RAB40C
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August 2017 |
Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
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March 2012 |
Phaser crystallographic software
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July 2007 |
Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
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January 1990 |
The RND1 Small GTPase: Main Functions and Emerging Role in Oncogenesis
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July 2019 |
The molecular machines that traffic signaling receptors into and out of cilia
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April 2018 |
The Thyroid Hormone-target Gene Rhes a Novel Crossroad for Neurological and Psychiatric Disorders: New Insights from Animal Models
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August 2018 |
The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses.
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journal
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January 1996 |
A New Member of the Rho Family, Rnd1, Promotes Disassembly of Actin Filament Structures and Loss of Cell Adhesion
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April 1998 |
T-coffee: a novel method for fast and accurate multiple sequence alignment 1 1Edited by J. Thornton
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September 2000 |
Di-Ras2 Protein Forms a Complex with SmgGDS Protein in Brain Cytosol in Order to Be in a Low Affinity State for Guanine Nucleotides
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August 2015 |
Establishment and characterization of 12 human colorectal-carcinoma cell lines
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June 1999 |
The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling
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December 2014 |
[20] Processing of X-ray diffraction data collected in oscillation mode
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book
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January 1997 |
Crystal Structure and Functional Analysis of Ras Binding to Its Effector Phosphoinositide 3-Kinase γ
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December 2000 |
K-Ras Populates Conformational States Differently from Its Isoform H-Ras and Oncogenic Mutant K-RasG12D
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June 2018 |
Rnd3 in Cancer: A Review of the Evidence for Tumor Promoter or Suppressor
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August 2016 |
A proteomics approach to understanding protein ubiquitination
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July 2003 |
UCSF Chimera?A visualization system for exploratory research and analysis
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January 2004 |
The Ras Superfamily of Small GTPases in Non-neoplastic Cerebral Diseases
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May 2019 |
In vivo genome editing using Staphylococcus aureus Cas9
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April 2015 |
DIRAS2 is Associated with Adult ADHD, Related Traits, and Co-Morbid Disorders
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July 2011 |
Rnd proteins: Multifunctional regulators of the cytoskeleton and cell cycle progression
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September 2010 |
Vesicle transport in oligodendrocytes: Probable role of Rab40c protein
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January 2004 |
Ubiquitination of K-Ras Enhances Activation and Facilitates Binding to Select Downstream Effectors
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March 2011 |
The Ras-RasGAP Complex: Structural Basis for GTPase Activation and Its Loss in Oncogenic Ras Mutants
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July 1997 |
The pre-hydrolysis state of p21ras in complex with GTP: new insights into the role of water molecules in the GTP hydrolysis reaction of ras-like proteins
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November 1999 |
NIH Image to ImageJ: 25 years of image analysis
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June 2012 |
RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network ("Rhesactome") in the striatum
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November 2016 |
KRAS and YAP1 Converge to Regulate EMT and Tumor Survival
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July 2014 |
Rhes, a striatal-enriched protein, promotes mitophagy via Nix
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November 2019 |
Guanine nucleotide-binding and autophosphorylating activities associated with the p21src protein of Harvey murine sarcoma virus
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October 1980 |
RAS Proteins and Their Regulators in Human Disease
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June 2017 |
Integrated RAS signaling defined by parallel NMR detection of effectors and regulators
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January 2014 |
Dynamic properties of the Ras switch I region and its importance for binding to effectors
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April 2001 |
Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II
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July 2008 |
RAS-related GTPases DIRAS1 and DIRAS2 induce autophagic cancer cell death and are required for autophagy in murine ovarian cancer cells
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March 2018 |
Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington's disease
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October 2015 |
Tracing Tumor Evolution in Sarcoma Reveals Clonal Origin of Advanced Metastasis
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September 2019 |
COSMIC: the Catalogue Of Somatic Mutations In Cancer
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October 2018 |
Distinct Binding Preferences between Ras and Raf Family Members and the Impact on Oncogenic Ras Signaling
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December 2019 |
Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding
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September 2015 |
Biochemical properties of the YPT-related rab 1B protein: Comparison with rab 1A
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October 1989 |
KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation
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February 2021 |
The small GTP-binding protein, Rhes, regulates signal transduction from G protein-coupled receptors
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January 2004 |
Interface analysis of small GTP binding protein complexes suggests preferred membrane orientations
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May 2017 |
RASSF tumor suppressor gene family: Biological functions and regulation
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March 2014 |
The CCPN data model for NMR spectroscopy: Development of a software pipeline
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April 2005 |
Generalized myoclonic epilepsy with photosensitivity in juvenile dogs caused by a defective DIRAS family GTPase 1
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February 2017 |
Regulation of RAS oncogenicity by acetylation
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journal
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June 2012 |
Discovery of Potent and Selective Covalent Inhibitors of JNK
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January 2012 |