skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: The Structure of the Arabidopsis PEX4-PEX22 Peroxin Complex-Insights Into Ubiquitination at the Pero

Journal Article · · Front. Cell Dev. Biol.,

Research Organization:
Argonne National Laboratory (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
DOE - Office Of Science; National Institutes of Health (NIH); OTHER
OSTI ID:
1863038
Journal Information:
Front. Cell Dev. Biol.,, Vol. 10
Country of Publication:
United States
Language:
ENGLISH

References (60)

The Pex4p–Pex22p complex from Hansenula polymorpha : biophysical analysis, crystallization and X-ray diffraction characterization journal January 2018
Genome-Wide Insertional Mutagenesis of Arabidopsis thaliana journal August 2003
Ubiquitylation in plants: a post-genomic look at a post-translational modification journal October 2001
Announcing the worldwide Protein Data Bank journal December 2003
Peroxisomal Ubiquitin-Protein Ligases Peroxin2 and Peroxin10 Have Distinct But Synergistic Roles in Matrix Protein Import and Peroxin5 Retrotranslocation in Arabidopsis     journal September 2014
Protein-protein interactions: General trends in the relationship between binding affinity and interfacial buried surface area: Protein-protein Interactions journal February 2013
Insights into the Role of the Peroxisomal Ubiquitination Machinery in Pex13p Degradation in the Yeast Hansenula polymorpha journal May 2018
Systematic Identification of Novel Protein Domain Families Associated with Nuclear Functions journal January 2002
The RING-type ubiquitin ligases Pex2p, Pex10p and Pex12p form a heteromeric complex that displays enhanced activity in an ubiquitin conjugating enzyme-selective manner: The RING-type ubiquitin ligases journal May 2012
The Cytosolic Domain of Pex22p Stimulates the Pex4p-Dependent Ubiquitination of the PTS1-Receptor journal August 2014
The Arabidopsis PEX12 Gene Is Required for Peroxisome Biogenesis and Is Essential for Development journal August 2005
Enzymatic assembly of DNA molecules up to several hundred kilobases journal April 2009
UCSF ChimeraX: Meeting modern challenges in visualization and analysis: UCSF ChimeraX Visualization System journal September 2017
A pex1 missense mutation improves peroxisome function in a subset of Arabidopsis pex6 mutants without restoring PEX5 recycling journal March 2018
Disparate peroxisome‐related defects in Arabidopsis pex6 and pex26 mutants link peroxisomal retrotranslocation and oil body utilization journal August 2017
Members of the E2D (UbcH5) Family Mediate the Ubiquitination of the Conserved Cysteine of Pex5p, the Peroxisomal Import Receptor journal May 2008
Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex journal February 2018
Ubiquitination of the glycosomal matrix protein receptor PEX5 in Trypanosoma brucei by PEX4 displays novel features journal December 2013
PhosPhAt: a database of phosphorylation sites in Arabidopsis thaliana and a plant-specific phosphorylation site predictor journal December 2007
Using Dali for Protein Structure Comparison book January 2020
FFAS03: a server for profile-profile sequence alignments journal July 2005
Highly accurate protein structure prediction with AlphaFold journal July 2021
Genetic Interactions between PEROXIN12 and Other Peroxisome-Associated Ubiquitination Components journal September 2016
Peroxisome Function, Biogenesis, and Dynamics in Plants journal October 2017
Elevated growth temperature decreases levels of the PEX5 peroxisome-targeting signal receptor and ameliorates defects of Arabidopsis mutants with an impaired PEX4 ubiquitin-conjugating enzyme journal September 2015
Arabidopsis RING Peroxins are E3 Ubiquitin Ligases that Interact with Two Homologous Ubiquitin Receptor Proteins F journal January 2013
Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity journal May 2016
Pex22p of Pichia pastoris, Essential for Peroxisomal Matrix Protein Import, Anchors the Ubiquitin-Conjugating Enzyme, Pex4p, on the Peroxisomal Membrane journal July 1999
Genome Analysis and Functional Characterization of the E2 and RING-Type E3 Ligase Ubiquitination Enzymes of Arabidopsis journal December 2005
Inference of Macromolecular Assemblies from Crystalline State journal September 2007
Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7 journal June 2008
PDBsum: Structural summaries of PDB entries journal October 2017
Oilseed isocitrate lyases lacking their essential type 1 peroxisomal targeting signal are piggybacked to glyoxysomes. journal February 1997
Peroxisome-associated matrix protein degradation in Arabidopsis journal February 2009
A MUB E2 structure reveals E1 selectivity between cognate ubiquitin E2s in eukaryotes journal August 2016
An oligomeric protein is imported into peroxisomes in vivo journal December 1994
A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms journal May 2013
Collaboration gets the most out of software journal September 2013
How are peroxisomes formed? The role of the endoplasmic reticulum and peroxins journal June 2001
Structure of a Ubiquitin E1-E2 Complex: Insights to E1-E2 Thioester Transfer journal March 2013
Assessment of the CASP14 assembly predictions journal August 2021
UCSF ChimeraX : Structure visualization for researchers, educators, and developers journal October 2020
Ubiquitination of the peroxisomal import receptor Pex5p is required for its recycling journal April 2007
Different functions of the C 3 HC 4 zinc RING finger peroxins PEX10, PEX2, and PEX12 in peroxisome formation and matrix protein import journal August 2010
Reducing PEX13 Expression Ameliorates Physiological Defects of Late-Acting Peroxin Mutants journal November 2010
Plant peroxisomes: recent discoveries in functional complexity, organelle homeostasis, and morphological dynamics journal December 2016
Deciphering key features in protein structures with the new ENDscript server journal April 2014
AthPEX10, a nuclear gene essential for peroxisome and storage organelle formation during Arabidopsis embryogenesis journal July 2003
An Arabidopsis pex10 Null Mutant Is Embryo Lethal, Implicating Peroxisomes in an Essential Role during Plant Embryogenesis journal October 2003
E2 enzymes: more than just middle men journal March 2016
Structural and Functional Insights to Ubiquitin-Like Protein Conjugation journal May 2014
Expression and Purification of Soluble His6-Tagged TEV Protease book January 2009
AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models journal November 2021
Pex10p functions as an E3 ligase for the Ubc4p-dependent ubiquitination of Pex5p journal October 2008
Insights into ubiquitin-conjugating enzyme/ co-activator interactions from the structure of the Pex4p:Pex22p complex: Crystal structure of the Pex4p:Pex22p complex journal November 2011
Pexophagy-linked degradation of the peroxisomal membrane protein Pex3p involves the ubiquitin–proteasome system journal August 2013
The increasing complexity of the ubiquitin code journal May 2016
An Arabidopsis indole-3-butyric acid-response mutant defective in PEROXIN6, an apparent ATPase implicated in peroxisomal function journal January 2004
Identification and Functional Characterization of Arabidopsis PEROXIN4 and the Interacting Protein PEROXIN22 journal November 2005
Genetic Analysis of Indole-3-butyric Acid Responses in Arabidopsis thaliana Reveals Four Mutant Classes journal November 2000