Drug resistance in Plasmodium
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January 2018 |
Malaria—Update on Antimalarial Resistance and Treatment Approaches
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January 2018 |
Biology of Malaria Transmission
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November 2016 |
A Research Agenda to Underpin Malaria Eradication
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January 2011 |
New developments in anti-malarial target candidate and product profiles
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journal
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January 2017 |
Natural Products: A Potential Source of Malaria Transmission Blocking Drugs?
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September 2020 |
Malaria parasite-infected erythrocytes inhibit glucose utilization in uninfected red cells
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journal
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October 2005 |
Glutathione stability and oxidative stress in P. falciparum infection in vitro: Responses of normal and G6PD deficient cells
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November 1982 |
A Second Target of the Antimalarial and Antibacterial Agent Fosmidomycin Revealed by Cellular Metabolic Profiling
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May 2011 |
Targeting DHFR in parasitic protozoa
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January 2005 |
Activity of PS-15 and its metabolite, WR99210, against Plasmodium falciparum in an in vivo-in vitro model
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September 1996 |
Isoxazolopyrimidine-Based Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Antimalarial Activity
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August 2018 |
Targeting Enzymes with Phosphonate-Based Inhibitors: Mimics of Tetrahedral Transition States and Stable Isosteric Analogues of Phosphates
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February 2006 |
Identification and Stoichiometry of Glycosylphosphatidylinositol-anchored Membrane Proteins of the Human Malaria Parasite Plasmodium falciparum
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July 2006 |
Hot, sweet and sticky: the glycobiology of Plasmodium falciparum
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May 2008 |
Structural analysis of the glycosyl-phosphatidylinositol membrane anchor of the merozoite surface proteins-1 and -2 of Plasmodium falciparum
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January 1996 |
Processing of Plasmodium falciparum Merozoite Surface Protein MSP1 Activates a Spectrin-Binding Function Enabling Parasite Egress from RBCs
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October 2015 |
Analysis of Antibodies Directed against Merozoite Surface Protein 1 of the Human Malaria Parasite Plasmodium falciparum
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February 2006 |
The Plasmodium falciparum rhoptry bulb protein RAMA plays an essential role in rhoptry neck morphogenesis and host red blood cell invasion
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September 2019 |
Malaria Derived Glycosylphosphatidylinositol Anchor Enhances Anti-Pfs25 Functional Antibodies That Block Malaria Transmission
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January 2018 |
Pfs230: from malaria transmission-blocking vaccine candidate toward function
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journal
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July 2003 |
The Pfs230 N-terminal fragment, Pfs230D1+: expression and characterization of a potential malaria transmission-blocking vaccine candidate
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November 2019 |
Outer membrane protein complex as a carrier for malaria transmission blocking antigen Pfs230
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July 2019 |
The RTS,S malaria vaccine
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July 2010 |
RTS,S/AS01 vaccine (Mosquirix™): an overview
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journal
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October 2019 |
R21/Matrix-M: a second malaria vaccine?
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May 2021 |
Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial
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May 2021 |
Circumsporozoite protein is required for development of malaria sporozoites in mosquitoes
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January 1997 |
Glycosylphosphatidylinositol Anchors Represent the Major Carbohydrate Modification in Proteins of Intraerythrocytic Stage Plasmodium falciparum
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March 1997 |
Suggestive Evidence for Darwinian Selection against Asparagine-Linked Glycans of Plasmodium falciparum and Toxoplasma gondii
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journal
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February 2010 |
The diversity of dolichol-linked precursors to Asn-linked glycans likely results from secondary loss of sets of glycosyltransferases
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journal
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January 2005 |
Sugar activation and glycosylation in Plasmodium
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journal
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October 2015 |
Uncovering the essential genes of the human malaria parasite Plasmodium falciparum by saturation mutagenesis
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journal
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May 2018 |
New insights into the blood-stage transcriptome of Plasmodium falciparum using RNA-Seq
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journal
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April 2010 |
Chromatin Accessibility-Based Characterization of the Gene Regulatory Network Underlying Plasmodium falciparum Blood-Stage Development
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journal
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April 2018 |
Directional gene expression and antisense transcripts in sexual and asexual stages of Plasmodium falciparum
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November 2011 |
The yeast SEC53 gene encodes phosphomannomutase.
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July 1988 |
The reaction mechanism of phosphomannomutase in plants
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journal
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January 1997 |
The glucose biphosphate family of enzymes
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journal
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June 1986 |
Expression of manB Gene from Escherichia coli in Lactococcus lactis and Characterization of Its Bifunctional Enzyme, Phosphomannomutase
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journal
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August 2018 |
Mammalian Phosphomannomutase PMM1 Is the Brain IMP-sensitive Glucose-1,6-bisphosphatase
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December 2008 |
Genetic analysis of phosphomannomutase/phosphoglucomutase from Vibrio furnissii and characterization of its role in virulence
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October 2003 |
Purification and characterization of phosphomannomutase/phosphoglucomutase from Pseudomonas aeruginosa involved in biosynthesis of both alginate and lipopolysaccharide.
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journal
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August 1994 |
Evolutionary trace analysis of the α-D-phosphohexomutase superfamily
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journal
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August 2004 |
Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites
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journal
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March 2016 |
Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion
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journal
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October 2017 |
HMDB 4.0: the human metabolome database for 2018
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journal
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November 2017 |
Screening the Medicines for Malaria Venture Pathogen Box for invasion and egress inhibitors of the blood stage of Plasmodium falciparum reveals several inhibitory compounds
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March 2020 |
Peptidic boronic acids are potent cell-permeable inhibitors of the malaria parasite egress serine protease SUB1
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journal
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May 2021 |
Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor
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journal
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May 2021 |
Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity
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journal
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July 2020 |
Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle
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April 2020 |
Selective Inhibition of a Two-step Egress of Malaria Parasites from the Host Erythrocyte
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September 2003 |
Molecular and functional aspects of parasite invasion
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December 2004 |
Inhibition of glycosyl-phosphatidylinositol biosynthesis in Plasmodium falciparum by C-2 substituted mannose analogues: P. falciparum GPtdIns glycosylation inhibition
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journal
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December 2001 |
Glycosylphosphatidylinositols synthesized by asexual erythrocytic stages of the malarial parasite, Plasmodium falciparum. Candidates for plasmodial glycosylphosphatidylinositol membrane anchor precursors and pathogenicity factors.
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journal
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January 1994 |
Biosynthesis of glycosyl phosphatidylinositol protein anchors
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journal
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December 1990 |
Developmental Stage-specific Biosynthesis of Glycosylphosphatidylinositol Anchors in IntraerythrocyticPlasmodium falciparum and Its Inhibition in a Novel Manner by Mannosamine
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journal
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August 2000 |
Glucosamine Inhibits Inositol Acylation of the Glycosylphosphatidylinositol Anchors in IntraerythrocyticPlasmodium falciparum
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journal
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January 2003 |
Statistical power analyses using G*Power 3.1: Tests for correlation and regression analyses
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journal
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November 2009 |
Evolutionary Genomics of the HAD Superfamily: Understanding the Structural Adaptations and Catalytic Diversity in a Superfamily of Phosphoesterases and Allied Enzymes
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journal
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September 2006 |
Haloacid Dehalogenase Proteins: Novel Mediators of Metabolic Plasticity in Plasmodium falciparum
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January 2019 |
A sugar phosphatase regulates the methylerythritol phosphate (MEP) pathway in malaria parasites
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July 2014 |
Suppression of Drug Resistance Reveals a Genetic Mechanism of Metabolic Plasticity in Malaria Parasites
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November 2018 |
The Metabolite Repair Enzyme Phosphoglycolate Phosphatase Regulates Central Carbon Metabolism and Fosmidomycin Sensitivity in Plasmodium falciparum
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December 2019 |
PMM (PMM1), the Human Homologue ofSEC53or Yeast Phosphomannomutase, Is Localized on Chromosome 22q13
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journal
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February 1997 |
Mutations in PMM2, a phosphomannomutase gene on chromosome 16p13 in carbohydrate-deficient glycoprotein type I syndrome (Jaeken syndrome)
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May 1997 |
Synthesis, Derivatization, and Structural Analysis of Phosphorylated Mono-, Di-, and Trifluorinated d -Gluco-heptuloses by Glucokinase: Tunable Phosphoglucomutase Inhibition
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April 2019 |
Inhibitory Evaluation of αPMM/PGM from Pseudomonas aeruginosa : Chemical Synthesis, Enzyme Kinetics, and Protein Crystallographic Study
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journal
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May 2019 |
Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1
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journal
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August 2015 |
The X-ray Crystal Structures of Human α-Phosphomannomutase 1 Reveal the Structural Basis of Congenital Disorder of Glycosylation Type 1a
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May 2006 |
Genome-wide Analysis of Substrate Specificities of the Escherichia coli Haloacid Dehalogenase-like Phosphatase Family
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September 2006 |
Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae: BIOCHEMICAL, STRUCTURAL, AND EVOLUTIONARY INSIGHTS
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journal
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June 2015 |
Genome sequence of the human malaria parasite Plasmodium falciparum
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journal
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October 2002 |
Characterization of α-phosphoglucomutase isozymes from Toxoplasma gondii
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journal
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June 2010 |
Multiprotein complex between the GPI-anchored CyRPA with PfRH5 and PfRipr is crucial for Plasmodium falciparum erythrocyte invasion
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journal
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January 2015 |
Prodrugs of biologically active phosphate esters
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journal
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March 2003 |
MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis
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journal
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August 2017 |
Esterase mutation is a mechanism of resistance to antimalarial compounds
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journal
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January 2017 |
Distinct roles for pbs21 and pbs25 in the in vitro ookinete to oocyst transformation of Plasmodium berghei
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journal
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October 2000 |
A Central Role for P48/45 in Malaria Parasite Male Gamete Fertility
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journal
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January 2001 |
Proteoglycans mediate malaria sporozoite targeting to the liver: Malaria sporozoite targeting to the liver
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journal
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July 2002 |
A Plasmodium falciparum C -mannosyltransferase is dispensable for parasite asexual blood stage development
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journal
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October 2019 |
Apicomplexan C-Mannosyltransferases Modify Thrombospondin Type I-containing Adhesins of the TRAP Family
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journal
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February 2018 |
Protein O-fucosylation in Plasmodium falciparum ensures efficient infection of mosquito and vertebrate hosts
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journal
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September 2017 |
Protein O-Fucosyltransferase 2 Is Not Essential for Plasmodium berghei Development
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July 2019 |
Efficient site-specific integration in Plasmodium falciparum chromosomes mediated by mycobacteriophage Bxb1 integrase
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July 2006 |
Malaria Parasite cGMP-dependent Protein Kinase Regulates Blood Stage Merozoite Secretory Organelle Discharge and Egress
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journal
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May 2013 |
Toxoplasma gondii Cyclic GMP-Dependent Kinase: Chemotherapeutic Targeting of an Essential Parasite Protein Kinase
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June 2002 |
Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development
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July 2010 |
A Facile Method for High-throughput Co-expression of Protein Pairs
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July 2004 |
A short translational ramp determines the efficiency of protein synthesis
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December 2019 |
Four plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidine
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January 2002 |
Assessment of Biological Role and Insight into Druggability of the Plasmodium falciparum Protease Plasmepsin V
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journal
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February 2020 |
Na+ Influx Induced by New Antimalarials Causes Rapid Alterations in the Cholesterol Content and Morphology of Plasmodium falciparum
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May 2016 |
HKL -3000: the integration of data reduction and structure solution – from diffraction images to an initial model in minutes
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July 2006 |
SWISS-MODEL: homology modelling of protein structures and complexes
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journal
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May 2018 |
Structural Basis of the Molecular Switch between Phosphatase and Mutase Functions of Human Phosphomannomutase 1 under Ischemic Conditions
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journal
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April 2018 |
Phaser crystallographic software
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journal
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July 2007 |
Coot model-building tools for molecular graphics
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November 2004 |
PHENIX: a comprehensive Python-based system for macromolecular structure solution
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January 2010 |
AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility
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December 2009 |
Avogadro: an advanced semantic chemical editor, visualization, and analysis platform
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journal
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August 2012 |
An expedient synthesis of benzyl 2,3,4-tri-O-benzyl-β-d-glucopyranoside and benzyl 2,3,4-tri-O-benzyl-β-d-mannopyranoside
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journal
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May 2005 |
Enzyme-catalyzed synthesis of isosteric phosphono-analogues of sugar nucleotides
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journal
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January 2009 |
Identification of an oxime-containing C-glucosylarene as a potential inhibitor of sodium-dependent glucose co-transporter 2
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journal
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January 2018 |
Stereospecific synthesis of the phosphono analogs of .alpha.- and .beta.-D-glucose 1-phosphate
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November 1982 |