Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization

Cherney, Emily C.; Zhang, Liping; Lo, Julian; Huynh, Tram; Wei, Donna; Ahuja, Vijay; Quesnelle, Claude; Schieven, Gary L.; Futran, Alan; Locke, Gregory A.; Lin, Zeyu; Monereau, Laura; Chaudhry, Charu; Blum, Jordan; Li, Sha; Fereshteh, Mark; Li-Wang, Bifang; Gangwar, Sanjeev; Pan, Chin; Chong, Colin; Zhu, Xiao; Posy, Shana L.; Sack, John S.; Zhang, Ping; Ruzanov, Max; Harner, Mary; Akhtar, Fahad; Schroeder, Gretchen M.; Vite, Gregory; Fink, Brian

doi:10.1021/acs.jmedchem.1c01986

Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization

Journal Article · 31 January 2022 · J. Med. Chem.

DOI:https://doi.org/10.1021/acs.jmedchem.1c01986· OSTI ID:1863031

Cherney, Emily C.; Zhang, Liping; Lo, Julian; Huynh, Tram; Wei, Donna; Ahuja, Vijay; Quesnelle, Claude; Schieven, Gary L.; Futran, Alan; Locke, Gregory A.; Lin, Zeyu; Monereau, Laura; Chaudhry, Charu; Blum, Jordan; Li, Sha; Fereshteh, Mark; Li-Wang, Bifang; Gangwar, Sanjeev; Pan, Chin; Chong, Colin more »

Research Organization:: Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)

Sponsoring Organization:: DOE - Office Of Science; INDUSTRY

OSTI ID:: 1863031

Journal Information:: J. Med. Chem., Journal Name: J. Med. Chem. Journal Issue: (4) Vol. 65

Country of Publication:: United States

Language:: ENGLISH

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