Preliminary data on rat feeding with beryllium
Abstract
At a dietary level of 5%, Be sulfate and Be carbonate completely inhibited growth of rats and caused some mortality. A rickets-like condition occurred in these rats. Food intake was reduced by about 50% but this did not account for all growth inhibition as shown by a paired feeding experiment. Return to stock diet after a prolonged period of ingestion of Be salt allowed rapid but not complete growth recovery. Be sulfate was more toxic to old rats than to weanlings, but with Be carbonate mature rats seemed to be more resistant than weanlings. Be carbonate at a level of 2.3% of the diet caused some weight depression in rats. Be metal at a 10% dietary level and Be oxide at a 5% dietary level did not affect the growth of rats. 11 figs., 2 tabs.
- Authors:
- Publication Date:
- Research Org.:
- Rochester Univ., NY (United States). Atomic Energy Project
- OSTI Identifier:
- 186229
- Report Number(s):
- M-1997
ON: DE95013624; TRN: 96:001173-0005
- Resource Type:
- Technical Report
- Resource Relation:
- Other Information: PBD: Sep 1947; Related Information: Is Part Of Progress report of preliminary studies of beryllium toxicity; Hodge, H.C.; PB: 136 p.
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 56 BIOLOGY AND MEDICINE, APPLIED STUDIES; 36 MATERIALS SCIENCE; 07 ISOTOPE AND RADIATION SOURCE TECHNOLOGY; BERYLLIUM SULFATES; TOXICITY; BERYLLIUM CARBONATES; RATS; BIOLOGICAL EFFECTS; MORTALITY; GROWTH; ALKALINE EARTH ISOTOPES
Citation Formats
Maynard, E.A., Downs, W.L., and Hodge, H.C.. Preliminary data on rat feeding with beryllium. United States: N. p., 1947.
Web. doi:10.2172/186229.
Maynard, E.A., Downs, W.L., & Hodge, H.C.. Preliminary data on rat feeding with beryllium. United States. doi:10.2172/186229.
Maynard, E.A., Downs, W.L., and Hodge, H.C.. Mon .
"Preliminary data on rat feeding with beryllium". United States.
doi:10.2172/186229. https://www.osti.gov/servlets/purl/186229.
@article{osti_186229,
title = {Preliminary data on rat feeding with beryllium},
author = {Maynard, E.A. and Downs, W.L. and Hodge, H.C.},
abstractNote = {At a dietary level of 5%, Be sulfate and Be carbonate completely inhibited growth of rats and caused some mortality. A rickets-like condition occurred in these rats. Food intake was reduced by about 50% but this did not account for all growth inhibition as shown by a paired feeding experiment. Return to stock diet after a prolonged period of ingestion of Be salt allowed rapid but not complete growth recovery. Be sulfate was more toxic to old rats than to weanlings, but with Be carbonate mature rats seemed to be more resistant than weanlings. Be carbonate at a level of 2.3% of the diet caused some weight depression in rats. Be metal at a 10% dietary level and Be oxide at a 5% dietary level did not affect the growth of rats. 11 figs., 2 tabs.},
doi = {10.2172/186229},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Sep 01 00:00:00 EDT 1947},
month = {Mon Sep 01 00:00:00 EDT 1947}
}
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