Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain

Li, Mingzong; Konteatis, Zenon; Nagaraja, Nelamangala; Chen, Yue; Zhou, Shubao; Ma, Guangning; Gross, Stefan; Marjon, Katya; Hyer, Marc L.; Mandley, Everton; Lein, Max; Padyana, Anil K.; Jin, Lei; Tong, Shuilong; Peters, Rachel; Murtie, Joshua; Travins, Jeremy; Medeiros, Matthew; Liu, Peng; Frank, Victoria; Judd, Evan T.; Biller, Scott A.; Marks, Kevin M.; Sui, Zhihua; Reznik, Samuel K.

doi:10.1021/acs.jmedchem.1c01595

Title: Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain

Journal Article · 01 March 2022 · J. Med. Chem.

DOI:https://doi.org/10.1021/acs.jmedchem.1c01595· OSTI ID:1861844

Li, Mingzong; Konteatis, Zenon; Nagaraja, Nelamangala; Chen, Yue; Zhou, Shubao; Ma, Guangning; Gross, Stefan; Marjon, Katya; Hyer, Marc L.; Mandley, Everton; Lein, Max; Padyana, Anil K.; Jin, Lei; Tong, Shuilong; Peters, Rachel; Murtie, Joshua; Travins, Jeremy; Medeiros, Matthew; Liu, Peng; Frank, Victoria more »

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Research Organization:: Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)

Sponsoring Organization:: DOE - Office Of Science; INDUSTRY

OSTI ID:: 1861844

Journal Information:: J. Med. Chem., Vol. 65, Issue (6)

Country of Publication:: United States

Language:: ENGLISH

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