The genes encoding {alpha}2(IX) collagen (COL9A2) map to human chromosome 1p32.3-p33 and mouse chromosome 4
Abstract
We have determined the chromosomal locations of the human and murine genes coding for {alpha}2(IX) collagen, a polypeptide subunit of the heterotrimeric type IX collagen molecule. COL9A2 was mapped to human chromosome 1p32.3-p33 using fluorescence in situ hybridization. A single-strand conformational polymorphism within the murine Col9a2 gene was used to map this locus to mouse chromosome 4. We also present new sequence data, which completes the coding information for the human {alpha}2(IX) chain. This permits comparison of the carboxyl-terminal (NC1) domains of the {alpha}1(IX), {alpha}2(IX), and {alpha}3(IX) chains across several species. 32 refs., 3 figs.
- Authors:
-
- Harvard Medical School, Boston, MA (United States); and others
- Publication Date:
- OSTI Identifier:
- 186064
- Resource Type:
- Journal Article
- Journal Name:
- Genomics
- Additional Journal Information:
- Journal Volume: 23; Journal Issue: 1; Other Information: PBD: 1 Sep 1994
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 55 BIOLOGY AND MEDICINE, BASIC STUDIES; GENETIC MAPPING; RESOLUTION; GENES; GENE MUTATIONS; DNA SEQUENCING; GENETIC VARIABILITY; COLLAGEN; HUMAN CHROMOSOME 1; CHROMOSOMES; MICE; DNA HYBRIDIZATION; POLYPEPTIDES; FLUORESCENCE; SPECIES DIVERSITY; DNA-CLONING; NUCLEOTIDES; AMINO ACID SEQUENCE
Citation Formats
Warman, M L, McCarthy, M T, and Olsen, B R. The genes encoding {alpha}2(IX) collagen (COL9A2) map to human chromosome 1p32.3-p33 and mouse chromosome 4. United States: N. p., 1994.
Web. doi:10.1006/geno.1994.1472.
Warman, M L, McCarthy, M T, & Olsen, B R. The genes encoding {alpha}2(IX) collagen (COL9A2) map to human chromosome 1p32.3-p33 and mouse chromosome 4. United States. https://doi.org/10.1006/geno.1994.1472
Warman, M L, McCarthy, M T, and Olsen, B R. 1994.
"The genes encoding {alpha}2(IX) collagen (COL9A2) map to human chromosome 1p32.3-p33 and mouse chromosome 4". United States. https://doi.org/10.1006/geno.1994.1472.
@article{osti_186064,
title = {The genes encoding {alpha}2(IX) collagen (COL9A2) map to human chromosome 1p32.3-p33 and mouse chromosome 4},
author = {Warman, M L and McCarthy, M T and Olsen, B R},
abstractNote = {We have determined the chromosomal locations of the human and murine genes coding for {alpha}2(IX) collagen, a polypeptide subunit of the heterotrimeric type IX collagen molecule. COL9A2 was mapped to human chromosome 1p32.3-p33 using fluorescence in situ hybridization. A single-strand conformational polymorphism within the murine Col9a2 gene was used to map this locus to mouse chromosome 4. We also present new sequence data, which completes the coding information for the human {alpha}2(IX) chain. This permits comparison of the carboxyl-terminal (NC1) domains of the {alpha}1(IX), {alpha}2(IX), and {alpha}3(IX) chains across several species. 32 refs., 3 figs.},
doi = {10.1006/geno.1994.1472},
url = {https://www.osti.gov/biblio/186064},
journal = {Genomics},
number = 1,
volume = 23,
place = {United States},
year = {Thu Sep 01 00:00:00 EDT 1994},
month = {Thu Sep 01 00:00:00 EDT 1994}
}
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