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Structure and Function of a Dual Reductase?Dehydratase Enzyme System Involved in p-Terphenyl Biosynt

Journal Article · · ACS Chem. Biol.

Research Organization:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
DOE - Office Of Science; National Institutes of Health (NIH); UNIVERSITY
OSTI ID:
1856425
Journal Information:
ACS Chem. Biol., Vol. 16, Issue (12)
Country of Publication:
United States
Language:
ENGLISH

References (56)

Natural Terphenyls:  Developments since 1877 May 2006
Metabolites from the Induced Expression of Cryptic Single Operons Found in the Genome of Burkholderia pseudomallei January 2011
Identification and catalytic characterization of a nonribosomal peptide synthetase-like (NRPS-like) enzyme involved in the biosynthesis of echosides from Streptomyces sp. LZ35 August 2014
A new p -terphenyl derivative from the insect-derived fungus Aspergillus candidus Bdf-2 and the synergistic effects of terphenyllin January 2020
Terfestatins B and C, New p -Terphenyl Glycosides Produced by Streptomyces sp. RM-5–8 May 2015
Studies on the Cytotoxicity of Asterriquinone Derivatives. January 1998
Hinnuliquinone, a C2-symmetric dimeric non-peptide fungal metabolite inhibitor of HIV-1 protease November 2004
Therapeutic Actions of an Insulin Receptor Activator and a Novel Peroxisome Proliferator-Activated Receptor γ Agonist in the Spontaneously Hypertensive Obese Rat Model of Metabolic Syndrome X April 2005
Terrequinone A biosynthesis through L-tryptophan oxidation, dimerization and bisprenylation August 2007
Venturicidin C, a new 20-membered macrolide produced by Streptomyces sp. TS-2-2 November 2013
Herbimycins D–F, Ansamycin Analogues from Streptomyce s sp. RM-7-15 August 2013
The native production of the sesquiterpene isopterocarpolone by Streptomyces sp. RM-14-6 November 2013
Spoxazomicin D and Oxachelin C, Potent Neuroprotective Carboxamides from the Appalachian Coal Fire-Associated Isolate Streptomyces sp. RM-14-6 December 2016
Bi- and Tetracyclic Spirotetronates from the Coal Mine Fire Isolate Streptomyces sp. LC-6-2 March 2017
Frenolicins C–G, Pyranonaphthoquinones from Streptomyces sp. RM-4-15 August 2013
Ruthmycin, a New Tetracyclic Polyketide from Streptomyces sp. RM-4-15 December 2013
Mullinamides A and B, new cyclopeptides produced by the Ruth Mullins coal mine fire isolate Streptomyces sp. RM-27-46 April 2014
Structure Determination, Functional Characterization, and Biosynthetic Implications of Nybomycin Metabolites from a Mining Reclamation Site-Associated Streptomyces December 2019
Structure and specificity of a permissive bacterial C-prenyltransferase February 2017
antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences June 2011
Insights into Secondary Metabolism from a Global Analysis of Prokaryotic Biosynthetic Gene Clusters July 2014
Characterization of the atromentin biosynthesis genes and enzymes in the homobasidiomycete Tapinella panuoides November 2008
A One-Pot Chemoenzymatic Synthesis for the Universal Precursor of Antidiabetes and Antiviral Bis-Indolylquinones June 2007
Medium- and short-chain dehydrogenase/reductase gene and protein families: The SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymes November 2008
The aldo-keto reductases (AKRs): Overview June 2015
Filling out the structural map of the NTF2-like superfamily November 2013
Structure of the polyketide cyclase SnoaL reveals a novel mechanism for enzymatic aldol condensation April 2004
Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027 July 2016
Crystal structure and functional analysis of tetracenomycin ARO/CYC: Implications for cyclization specificity of aromatic polyketides April 2008
An Approach to 3,6-Disubstituted 2,5-Dioxybenzoquinones via Two Sequential Suzuki Couplings. Three-Step Synthesis of Leucomelone January 2009
Characterization of t yl M3/ t yl M2 and m yd C/ m yc B Pairs Required for Efficient Glycosyltransfer in Macrolide Antibiotic Biosynthesis December 2004
Enzymatic competition and cooperation branch the caerulomycin biosynthetic pathway toward different 2,2′-bipyridine members January 2017
Promiscuous Enzymes Cooperate at the Substrate Level En Route to Lactazole A July 2020
Natural and synthetic quinones and their reduction by the quinone reductase enzyme NQO1: from synthetic organic chemistry to compounds with anticancer potential January 2008
Protein superfamilles and domain superfolds December 1994
The Methionine-aromatic Motif Plays a Unique Role in Stabilizing Protein Structure August 2012
Predictive energy landscapes for protein-protein association November 2012
Morphology of protein–protein interfaces April 1998
SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis September 2017
Regiospecific Synthesis of Calcium‐Independent Daptomycin Antibiotics using a Chemoenzymatic Method January 2021
Mechanistic studies of an unprecedented enzyme-catalysed 1,2-phosphono-migration reaction April 2013
Oxidative Cyclization in Natural Product Biosynthesis December 2016
Heteroatom–Heteroatom Bond Formation in Natural Product Biosynthesis April 2017
Two Cooperative Glycosyltransferases Are Responsible for the Sugar Diversity of Saquayamycins Isolated from Streptomyces sp. KY 40-1 September 2017
Cooperation of Two Bifunctional Enzymes in the Biosynthesis and Attachment of Deoxysugars of the Antitumor Antibiotic Mithramycin September 2012
Characterization of Glycosyltransferase DesVII and Its Auxiliary Partner Protein DesVIII in the Methymycin/Pikromycin Biosynthetic Pathway August 2010
Cooperative Involvement of Glycosyltransferases in the Transfer of Amino Sugars during the Biosynthesis of the Macrolactam Sipanmycin by Streptomyces sp. Strain CS149 September 2018
Structure of Rhodococcus erythropolis limonene-1,2-epoxide hydrolase reveals a novel active site June 2003
Geneious Basic: An integrated and extendable desktop software platform for the organization and analysis of sequence data April 2012
iMOSFLM : a new graphical interface for diffraction-image processing with MOSFLM March 2011
Robust background modelling in DIALS October 2016
XDS January 2010
PHENIX: a comprehensive Python-based system for macromolecular structure solution January 2010
A short history of SHELX December 2007
Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7 June 2008
Features and development of Coot March 2010