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Dedifferentiation of Neurons and Astrocytes by Oncogenes Can Induce Gliomas in Mice
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October 2012 |
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The non-small cell lung cancer EGFR extracellular domain mutation, M277E, is oncogenic and drug-sensitive
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January 2017 |
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Putting together structures of epidermal growth factor receptors
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December 2014 |
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Crystal Structure of a Truncated Epidermal Growth Factor Receptor Extracellular Domain Bound to Transforming Growth Factor α
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September 2002 |
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Insulin and epidermal growth factor receptor family members share parallel activation mechanisms
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April 2020 |
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EGF Activates Its Receptor by Removing Interactions that Autoinhibit Ectodomain Dimerization
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February 2003 |
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Functional selectivity of EGF family peptide growth factors: Implications for cancer
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April 2009 |
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Extracellular domains drive homo- but not hetero-dimerization of erbB receptors
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September 2000 |
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EGFR Phosphorylates Tumor-Derived EGFRvIII Driving STAT3/5 and Progression in Glioblastoma
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October 2013 |
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Multistrip Western Blotting: A Tool for Comparative Quantitative Analysis of Multiple Proteins
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January 2015 |
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Use of TLS parameters to model anisotropic displacements in macromolecular refinement
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January 2001 |
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PHENIX: a comprehensive Python-based system for macromolecular structure solution
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January 2010 |
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Structures of Adnectin/Protein Complexes Reveal an Expanded Binding Footprint
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February 2012 |
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COSMIC: the Catalogue Of Somatic Mutations In Cancer
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October 2018 |
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The Somatic Genomic Landscape of Glioblastoma
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October 2013 |
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Enzymatic Prenylation and Oxime Ligation for the Synthesis of Stable and Homogeneous Protein-Drug Conjugates for Targeted Therapy
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August 2015 |
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Prognostic Effect of Epidermal Growth Factor Receptor and EGFRvIII in Glioblastoma Multiforme Patients
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February 2005 |
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EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics
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October 2017 |
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Structure−Function Studies of Ligand-Induced Epidermal Growth Factor Receptor Dimerization
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March 1998 |
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EGF receptor ligands: recent advances
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January 2016 |
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Complex Relationship between Ligand Binding and Dimerization in the Epidermal Growth Factor Receptor
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November 2014 |
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Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope
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April 2019 |
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EGFR heterogeneity and implications for therapeutic intervention in glioblastoma
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October 2017 |
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MolProbity : all-atom structure validation for macromolecular crystallography
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December 2009 |
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Phaser crystallographic software
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July 2007 |
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Epidermal growth factor receptor and EGFRvIII in glioblastoma: signaling pathways and targeted therapies
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January 2018 |
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The CCP4 suite programs for protein crystallography
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September 1994 |
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EGFRvIII gene rearrangement is an early event in glioblastoma tumorigenesis and expression defines a hierarchy modulated by epigenetic mechanisms
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July 2012 |
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Structures of the HER2–HER3–NRG1β complex reveal a dynamic dimer interface
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November 2021 |
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Oncogenic ERBB3 Mutations in Human Cancers
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May 2013 |
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Epidermal growth factor receptor mutations in lung cancer
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March 2007 |
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A compendium of mutational cancer driver genes
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August 2020 |
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ATSAS 3.0 : expanded functionality and new tools for small-angle scattering data analysis
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February 2021 |
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ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptor
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August 2009 |
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Modulation of the receptor binding affinity of amphiregulin by modification of its carboxyl terminal tail
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April 1995 |
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Systematic Functional Annotation of Somatic Mutations in Cancer
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March 2018 |
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Targeting a Glioblastoma Cancer Stem-Cell Population Defined by EGF Receptor Variant III
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December 2013 |
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A method of high-throughput functional evaluation of EGFR gene variants of unknown significance in cancer
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November 2017 |
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COOH-terminal Extended Recombinant Amphiregulin with Bioactivity Comparable with Naturally Derived Growth Factor
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July 1996 |
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Structural and mechanistic underpinnings of the differential drug sensitivity of EGFR mutations in non-small cell lung cancer
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March 2010 |
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Crystal Structure of the Complex of Human Epidermal Growth Factor and Receptor Extracellular Domains
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September 2002 |
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Structural Evidence for Loose Linkage between Ligand Binding and Kinase Activation in the Epidermal Growth Factor Receptor
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September 2010 |
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A single ligand is sufficient to activate EGFR dimers
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June 2012 |
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Cell-of-origin susceptibility to glioblastoma formation declines with neural lineage restriction
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February 2019 |
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Heterogeneity in EGF-binding affinities arises from negative cooperativity in an aggregating system
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December 2007 |
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Coot model-building tools for molecular graphics
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November 2004 |
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EGFR Cooperates with EGFRvIII to Recruit Macrophages in Glioblastoma
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November 2018 |
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Different Epidermal Growth Factor (EGF) Receptor Ligands Show Distinct Kinetics and Biased or Partial Agonism for Homodimer and Heterodimer Formation
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September 2014 |
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Cell-free synthesis of functional antibody fragments to provide a structural basis for antibody–antigen interaction
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February 2018 |
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Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
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April 2005 |
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Epidermal Growth Factor Receptor Dimerization and Activation Require Ligand-Induced Conformational Changes in the Dimer Interface
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August 2005 |
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Kinetics of receptor tyrosine kinase activation define ERK signaling dynamics
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August 2020 |
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XDS
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January 2010 |
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BioXTAS RAW : improvements to a free open-source program for small-angle X-ray scattering data reduction and analysis
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September 2017 |
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Polder maps: improving OMIT maps by excluding bulk solvent
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February 2017 |
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Structural Basis for Negative Cooperativity in Growth Factor Binding to an EGF Receptor
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August 2010 |
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Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development
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July 2018 |
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Two EGF molecules contribute additively to stabilization of the EGFR dimer
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January 1997 |
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Megabase-scale deletion using CRISPR/Cas9 to generate a fully haploid human cell line
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November 2014 |
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Epidermal Growth Factor Receptor Activation in Glioblastoma through Novel Missense Mutations in the Extracellular Domain
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December 2006 |
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Structure-Based View of Epidermal Growth Factor Receptor Regulation
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June 2008 |
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Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER
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March 2012 |