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Structure and function of an effector domain in antiviral factors and tumor suppressors SAMD9 and SA

Journal Article · · Proc. Natl. Acad. Sci. USA
Research Organization:
Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)
Sponsoring Organization:
DOE - Office Of Science; NIH
OSTI ID:
1856394
Journal Information:
Proc. Natl. Acad. Sci. USA, Journal Name: Proc. Natl. Acad. Sci. USA Journal Issue: (4) Vol. 119
Country of Publication:
United States
Language:
ENGLISH

References (32)

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 journal December 2014
Gain-of-function SAMD9L mutations cause a syndrome of cytopenia, immunodeficiency, MDS, and neurological symptoms journal April 2017
Human Host Range Restriction of the Vaccinia Virus C7/K1 Double Deletion Mutant Is Mediated by an Atypical Mode of Translation Inhibition journal September 2018
Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans journal March 2017
Crystal Structure of Archaeal Chromatin Protein Alba2-Double-stranded DNA Complex from Aeropyrum pernix K1 journal March 2012
The enigma of monosomy 7 journal June 2018
SAMD9 and SAMD9L in inherited predisposition to ataxia, pancytopenia, and myeloid malignancies journal February 2018
An interaction domain in human SAMD9 is essential for myxoma virus host-range determinant M062 antagonism of host anti-viral function journal March 2017
M062 Is a Host Range Factor Essential for Myxoma Virus Pathogenesis and Functions as an Antagonist of Host SAMD9 in Human Cells journal January 2011
Ataxia-Pancytopenia Syndrome Is Caused by Missense Mutations in SAMD9L journal June 2016
Germline SAMD9L truncation variants trigger global translational repression journal March 2021
Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions journal November 2004
Identification of Restriction Factors by Human Genome-Wide RNA Interference Screening of Viral Host Range Mutants Exemplified by Discovery of SAMD9 and WDR6 as Inhibitors of the Vaccinia Virus K1L−C7L− Mutant journal August 2015
SunRiSE: measuring translation elongation at single cell resolution by flow cytometry journal January 2018
The cowpox virus host range gene, CP77, affects phosphorylation of eIF2 α and vaccinia viral translation in apoptotic HeLa cells journal November 2004
PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools journal November 2018
Vaccinia Virus K1L and C7L Inhibit Antiviral Activities Induced by Type I Interferons journal August 2009
Structural basis for antagonism of human interleukin 18 by poxvirus interleukin 18-binding protein journal December 2008
The genomic landscape of pediatric myelodysplastic syndromes journal November 2017
Pediatric MDS and bone marrow failure-associated germline mutations in SAMD9 and SAMD9L impair multiple pathways in primary hematopoietic cells journal March 2021
Vaccinia virus K1L protein supports viral replication in human and rabbit cells through a cell-type-specific set of its ankyrin repeat residues that are distinct from its binding site for ACAP2 journal September 2006
A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection journal February 2018
The Alba protein family: Structure and function journal May 2016
Host range deletion mutant of vaccinia virus defective in human cells journal June 1981
Human sterile alpha motif domain 9, a novel gene identified as down-regulated in aggressive fibromatosis, is absent in the mouse journal April 2007
SAMD9 mutations cause a novel multisystem disorder, MIRAGE syndrome, and are associated with loss of chromosome 7 journal May 2016
Identification from diverse mammalian poxviruses of host-range regulatory genes functioning equivalently to vaccinia virus C7L journal March 2008
Haploinsufficiency of SAMD9L, an Endosome Fusion Facilitator, Causes Myeloid Malignancies in Mice Mimicking Human Diseases with Monosomy 7 journal September 2013
Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases journal February 2020
The complex domain architecture of SAMD9 family proteins, predicted STAND-like NTPases, suggests new links to inflammation and apoptosis journal May 2017
Identification of CP77 as the Third Orthopoxvirus SAMD9 and SAMD9L Inhibitor with Unique Specificity for a Rodent SAMD9L journal March 2019
SAMD9L autoinflammatory or ataxia pancytopenia disease mutations activate cell-autonomous translational repression journal August 2021

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