Identification and optimization of molecular glue compounds that inhibit a noncovalent E2 enzyme – ubiquitin complex

St-Cyr, Daniel; Ceccarelli, Derek F.; Orlicky, Stephen; van der Sloot, Almer M.; Tang, Xiaojing; Kelso, Susan; Moore, Susan; James, Clint; Posternak, Ganna; Coulombe-Huntington, Jasmin; Bertomeu, Thierry; Marinier, Anne; Sicheri, Frank; Tyers, Mike

doi:10.1126/sciadv.abi5797

Identification and optimization of molecular glue compounds that inhibit a noncovalent E2 enzyme – ubiquitin complex

Journal Article · 01 October 2021 · Science Advances

DOI:https://doi.org/10.1126/sciadv.abi5797· OSTI ID:1847714

St-Cyr, Daniel; Ceccarelli, Derek F.; Orlicky, Stephen; van der Sloot, Almer M.; Tang, Xiaojing; Kelso, Susan; Moore, Susan; James, Clint; Posternak, Ganna; Coulombe-Huntington, Jasmin; Bertomeu, Thierry; Marinier, Anne; Sicheri, Frank; Tyers, Mike

Research Organization:: Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)

Sponsoring Organization:: DOE - Office Of Science; FOREIGN

OSTI ID:: 1847714

Journal Information:: Science Advances, Journal Name: Science Advances Journal Issue: (44) Vol. 7; ISSN 2375-2548

Publisher:: AAAS

Country of Publication:: United States

Language:: ENGLISH

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