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Crystal structure of the Tspan15 LEL domain reveals a conserved ADAM10 binding site

Journal Article · · Structure

Research Organization:
Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)
Sponsoring Organization:
DOE - Office Of Science; NIH
OSTI ID:
1847712
Journal Information:
Structure, Journal Name: Structure Journal Issue: (2) Vol. 30
Country of Publication:
United States
Language:
ENGLISH

References (50)

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The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts journal October 2002
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Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket journal November 2016
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A Dock-and-Lock Mechanism Clusters ADAM10 at Cell-Cell Junctions to Promote α-Toxin Cytotoxicity journal November 2018
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The tetraspanin Tspan15 is an essential subunit of an ADAM10 scissor complex journal September 2020
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TspanC8 Tetraspanins and A Disintegrin and Metalloprotease 10 (ADAM10) Interact via Their Extracellular Regions: EVIDENCE FOR DISTINCT BINDING MECHANISMS FOR DIFFERENT TspanC8 PROTEINS journal December 2015
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ADAM-10-Mediated N-Cadherin Cleavage Is Protein Kinase C-  Dependent and Promotes Glioblastoma Cell Migration journal April 2009

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