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Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine-based inhibito

Journal Article · · Protein Sci.
DOI:https://doi.org/10.1002/pro.3361· OSTI ID:1847691

Research Organization:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
DOE - Office Of Science; INDUSTRY
OSTI ID:
1847691
Journal Information:
Protein Sci., Vol. 27, Issue (3)
Country of Publication:
United States
Language:
ENGLISH

References (21)

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PICK1 ICA69 Heteromeric BAR Domain Complex Regulates Synaptic Targeting and Surface Expression of AMPA Receptors journal November 2007
PDZ Domain Protein-Protein Interactions: A Case Study with PICK1 journal January 2007
Functional Modulation of the Glutamate Transporter Variant GLT1b by the PDZ Domain Protein PICK1 journal July 2013
Synapto-depressive effects of amyloid beta require PICK1 journal April 2014
Clustering of AMPA Receptors by the Synaptic PDZ Domain–Containing Protein PICK1 journal January 1999
PICK1 is a calcium-sensor for NMDA-induced AMPA receptor trafficking journal September 2005
Recognition of Unique Carboxyl-Terminal Motifs by Distinct PDZ Domains journal January 1997
Interaction prediction and classification of PDZ domains journal June 2010
Molecular Determinants for the Complex Binding Specificity of the PDZ Domain in PICK1 journal May 2005
PDZ Domains: Structural Modules for Protein Complex Assembly journal February 2002
Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions journal April 2007
Redox-Regulated Lipid Membrane Binding of the PICK1 PDZ Domain journal June 2010
Clustering and synaptic targeting of PICK1 requires direct interaction between the PDZ domain and lipid membranes journal October 2007
Discovery of Low-Molecular-Weight Ligands for the AF6 PDZ Domain journal June 2006
Sulindac Inhibits Canonical Wnt Signaling by Blocking the PDZ Domain of the Protein Dishevelled journal August 2009
Discovery, Structure-Activity Relationship Studies, and Crystal Structure of Nonpeptide Inhibitors Bound to the Shank3 PDZ Domain journal May 2011
Molecular replacement with MOLREP journal December 2009
Efficient anisotropic refinement of macromolecular structures using FFT journal January 1999
Coot model-building tools for molecular graphics journal November 2004
Mass Spectrometry Assisted Assignment of NMR Resonances in Reductively 13 C-Methylated Proteins journal November 2005