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Crystal Structure of a Retroviral Polyprotein: Prototype Foamy Virus Protease-Reverse Transcriptase

Journal Article · · Viruses-Basel
DOI:https://doi.org/10.3390/v13081495· OSTI ID:1844700
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Research Organization:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
DOE - Office Of Science; NCI; National Institutes of Health (NIH)
OSTI ID:
1844700
Journal Information:
Viruses-Basel, Vol. 13, Issue (8)
Country of Publication:
United States
Language:
ENGLISH

References (47)

Prototype Foamy Virus Protease Activity Is Essential for Intraparticle Reverse Transcription Initiation but Not Absolutely Required for Uncoating upon Host Cell Entry March 2013
Foamy Virus Assembly with Emphasis on Pol Encapsidation March 2013
Foamy Viruses Are Unconventional Retroviruses March 1999
Evidence that the Human Foamy Virus Genome Is DNA February 1999
Why aren’t foamy viruses pathogenic? June 2000
The Roles of Pol and Env in the Assembly Pathway of Human Foamy Virus May 1998
Role of the Foamy Virus Pol Cleavage Site in Viral Replication May 2007
Structural and functional insights into alphavirus polyprotein processing and pathogenesis September 2012
Human Foamy Virus Replication: A Pathway Distinct from That of Retroviruses and Hepadnaviruses March 1996
Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody fab fragment at 2.8 Å resolution December 1998
Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry March 2014
Comparative Studies on Retroviral Proteases: Substrate Specificity January 2010
The human foamy virus pol gene is expressed as a Pro-Pol polyprotein and not as a Gag-Pol fusion protein February 1996
Molecular Characterization of Proteolytic Processing of the Pol Proteins of Human Foamy Virus Reveals Novel Features of the Viral Protease September 1998
Structural and Functional Aspects of Foamy Virus Protease-Reverse Transcriptase July 2019
Evolution of Foamy Viruses: The Most Ancient of All Retroviruses September 2013
Retrovirus protease characterized as a dimeric aspartic proteinase May 1989
Formation of transient dimers by a retroviral protease March 2010
Foamy Retrovirus Integrase Contains a Pol Dimerization Domain Required for Protease Activation December 2010
Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer. July 1994
Selective unfolding of one Ribonuclease H domain of HIV reverse transcriptase is linked to homodimer formation February 2014
Asymmetric conformational maturation of HIV-1 reverse transcriptase June 2015
An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol January 2008
CCP 4 i 2: the new graphical user interface to the CCP 4 program suite February 2018
Coot model-building tools for molecular graphics November 2004
The Phenix software for automated determination of macromolecular structures September 2011
Refinement of Macromolecular Structures by the Maximum-Likelihood Method May 1997
Characterization of the Polymerase and RNase H Activities of Human Foamy Virus Reverse Transcriptase June 2004
Mutation of the Catalytic Domain of the Foamy Virus Reverse Transcriptase Leads to Loss of Processivity and Infectivity August 2002
HIV-1 reverse transcriptase complex with DNA and nevirapine reveals non-nucleoside inhibition mechanism January 2012
Structure of HIV-1 RT/dsRNA initiation complex prior to nucleotide incorporation March 2019
Trapping HIV-1 Reverse Transcriptase Before and After Translocation on DNA January 2003
Correlation between stability of a protein and its dipeptide composition: a novel approach for predicting in vivo stability of a protein from its primary sequence January 1990
Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease August 1989
Characterizing early drug resistance-related events using geometric ensembles from HIV protease dynamics December 2018
Solution Structure of the Mature HIV-1 Protease Monomer October 2003
Buried surface analysis of HIV-1 reverse transcriptase p66/p51 heterodimer and its interaction with dsDNA template/primer June 1994
Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA. July 1993
Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor June 1992
Ribonuclease H: properties, substrate specificity and roles in retroviral reverse transcription: Retroviral RNases H February 2009
Protein-protein interactions: General trends in the relationship between binding affinity and interfacial buried surface area: Protein-protein Interactions February 2013
The nature of the accessible and buried surfaces in proteins July 1976
Stock-based detection of protein oligomeric states in jsPISA April 2015
Inference of Macromolecular Assemblies from Crystalline State September 2007
Trapping of a catalytic HIV reverse transcriptase·template:primer complex through a disulfide bond May 2000
Purification and characterization of poliovirus polypeptide 3CD, a proteinase and a precursor for RNA polymerase December 1992
Viral precursor polyproteins: keys of regulation from replication to maturation April 2013

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