Effector-mediated membrane disruption controls cell death in CBASS antiphage defense

Duncan-Lowey, Brianna; McNamara-Bordewick, Nora K.; Tal, Nitzan; Sorek, Rotem; Kranzusch, Philip J.

doi:10.1016/j.molcel.2021.10.020

Effector-mediated membrane disruption controls cell death in CBASS antiphage defense

Journal Article · 01 December 2021 · Mol. Cell

DOI:https://doi.org/10.1016/j.molcel.2021.10.020· OSTI ID:1844691

Duncan-Lowey, Brianna; McNamara-Bordewick, Nora K.; Tal, Nitzan; Sorek, Rotem; Kranzusch, Philip J.

Research Organization:: Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)

Sponsoring Organization:: DOE - Office Of Science

OSTI ID:: 1844691

Journal Information:: Mol. Cell, Vol. 81, Issue (24)

Country of Publication:: United States

Language:: ENGLISH

References (42)

PHENIX: a comprehensive Python-based system for macromolecular structure solution No authors listed Acta Crystallographica Section D Biological Crystallography https://doi.org/10.1107/S0907444909052925		January 2010
Prokaryotic viperins produce diverse antiviral molecules No authors listed Nature https://doi.org/10.1038/s41586-020-2762-2		September 2020
Comparative genomic analyses reveal a vast, novel network of nucleotide-centric systems in biological conflicts, immunity and signaling No authors listed Nucleic Acids Research https://doi.org/10.1093/nar/gkv1267		November 2015
MolProbity : all-atom structure validation for macromolecular crystallography No authors listed Acta Crystallographica Section D Biological Crystallography https://doi.org/10.1107/S0907444909042073		December 2009
Cyclic GMP–AMP signalling protects bacteria against viral infection No authors listed Nature https://doi.org/10.1038/s41586-019-1605-5		September 2019
Pore-forming toxins: ancient, but never really out of fashion No authors listed Nature Reviews Microbiology https://doi.org/10.1038/nrmicro.2015.3		December 2015
Micron-scale holes terminate the phage infection cycle No authors listed Proceedings of the National Academy of Sciences https://doi.org/10.1073/pnas.0914030107		January 2010
De novo design of a fluorescence-activating β-barrel No authors listed Nature https://doi.org/10.1038/s41586-018-0509-0		September 2018
Coot model-building tools for molecular graphics No authors listed Acta Crystallographica Section D Biological Crystallography https://doi.org/10.1107/S0907444904019158		November 2004
Molecular basis of CD-NTase nucleotide selection in CBASS anti-phage defense No authors listed Cell Reports https://doi.org/10.1016/j.celrep.2021.109206		June 2021
Improved LC/MS Methods for the Analysis of Metal-Sensitive Analytes Using Medronic Acid as a Mobile Phase Additive No authors listed Analytical Chemistry https://doi.org/10.1021/acs.analchem.8b02100		July 2018
CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4 Cleavage with ApA>p Formation Terminating RNase Activity No authors listed Molecular Cell https://doi.org/10.1016/j.molcel.2019.06.014		September 2019
Highly accurate protein structure prediction with AlphaFold No authors listed Nature https://doi.org/10.1038/s41586-021-03819-2		July 2021
XDS No authors listed Acta Crystallographica Section D Biological Crystallography https://doi.org/10.1107/S0907444909047337		January 2010
Linking Crystallographic Model and Data Quality No authors listed Science https://doi.org/10.1126/science.1218231		May 2012
Structure-based design of a streptavidin mutant specific for an artificial biotin analogue No authors listed The Journal of Biochemistry https://doi.org/10.1093/jb/mvv004		February 2015
Predicting transmembrane protein topology with a hidden markov model: application to complete genomes11Edited by F. Cohen No authors listed Journal of Molecular Biology https://doi.org/10.1006/jmbi.2000.4315		January 2001
Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity No authors listed Molecular Cell https://doi.org/10.1016/j.molcel.2019.12.010		February 2020
Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix No authors listed Acta Crystallographica Section D Structural Biology https://doi.org/10.1107/S2059798319011471		October 2019
Abortive Infection: Bacterial Suicide as an Antiviral Immune Strategy No authors listed Annual Review of Virology https://doi.org/10.1146/annurev-virology-011620-040628		September 2020
CBASS Immunity Uses CARF-Related Effectors to Sense 3′–5′- and 2′–5′-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection No authors listed Cell https://doi.org/10.1016/j.cell.2020.05.019		July 2020
Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State No authors listed Immunity https://doi.org/10.1016/j.immuni.2017.02.014		March 2017
Diversity and classification of cyclic-oligonucleotide-based anti-phage signalling systems No authors listed Nature Microbiology https://doi.org/10.1038/s41564-020-0777-y		August 2020
STING cyclic dinucleotide sensing originated in bacteria No authors listed Nature https://doi.org/10.1038/s41586-020-2719-5		September 2020
The structure of a cytolytic α-helical toxin pore reveals its assembly mechanism No authors listed Nature https://doi.org/10.1038/nature08026		May 2009
Structural basis for the endoribonuclease activity of the type III-A CRISPR-associated protein Csm6 No authors listed RNA https://doi.org/10.1261/rna.054098.115		January 2016
Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding No authors listed Immunity https://doi.org/10.1016/j.immuni.2012.03.019		June 2012
Visualization of pinholin lesions in vivo No authors listed Proceedings of the National Academy of Sciences https://doi.org/10.1073/pnas.1222283110		May 2013
Direct activation of a phospholipase by cyclic GMP-AMP in El Tor Vibrio cholerae No authors listed Proceedings of the National Academy of Sciences https://doi.org/10.1073/pnas.1801233115		June 2018
Pfam: A comprehensive database of protein domain families based on seed alignments No authors listed Proteins: Structure, Function, and Genetics https://doi.org/10.1002/(SICI)1097-0134(199707)28:3<405::AID-PROT10>3.0.CO;2-L		July 1997
MMseqs2 enables sensitive protein sequence searching for the analysis of massive data sets No authors listed Nature Biotechnology https://doi.org/10.1038/nbt.3988		October 2017
The phage-host arms race: Shaping the evolution of microbes No authors listed BioEssays https://doi.org/10.1002/bies.201000071		October 2010
Disruption of lipid homeostasis in the Gram-negative cell envelope activates a novel cell death pathway No authors listed Proceedings of the National Academy of Sciences https://doi.org/10.1073/pnas.1601375113		February 2016
Structural basis for self-assembly of a cytolytic pore lined by protein and lipid No authors listed Nature Communications https://doi.org/10.1038/ncomms7337		February 2015
Daughter cell separation is controlled by cytokinetic ring-activated cell wall hydrolysis No authors listed The EMBO Journal https://doi.org/10.1038/emboj.2010.36		March 2010
Global indicators of X-ray data quality No authors listed Journal of Applied Crystallography https://doi.org/10.1107/S0021889800018227		April 2001
Bacterial cGAS-like enzymes synthesize diverse nucleotide signals No authors listed Nature https://doi.org/10.1038/s41586-019-0953-5		February 2019
HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity No authors listed Molecular Cell https://doi.org/10.1016/j.molcel.2019.12.009		February 2020
Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING No authors listed Molecular Cell https://doi.org/10.1016/j.molcel.2012.05.029		June 2012
Phages will out: strategies of host cell lysis No authors listed Trends in Microbiology https://doi.org/10.1016/S0966-842X(00)01705-4		March 2000
Structure of the Human cGAS–DNA Complex Reveals Enhanced Control of Immune Surveillance No authors listed Cell https://doi.org/10.1016/j.cell.2018.06.026		July 2018
A Completely Reimplemented MPI Bioinformatics Toolkit with a New HHpred Server at its Core No authors listed Journal of Molecular Biology https://doi.org/10.1016/j.jmb.2017.12.007		July 2018

Similar Records

Chrysin disrupts intracellular homeostasis through mitochondria-mediated cell death in human choriocarcinoma cells

Journal Article · 2018 · Biochemical and Biophysical Research Communications · OSTI ID:23134256

Park, Wonhyoung; Park, Sunwoo; Lim, Whasun; +1 more

Synergistic defense system by cooperative natural effectors against metastasis of B16 melanoma cells in H-2-associated control: different behavior of H-2+ and H-2- cells in metastatic processes

Journal Article · 1986 · J. Immunol.; (United States) · OSTI ID:5231113

Kawano, Y; Taniguchi, K; Toshitani, A; +1 more

CBASS Immunity Uses CARF-Related Effectors to Sense 3'–5'- and 2'–5'-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection

Journal Article · 2020 · Cell · OSTI ID:1638726

Lowey, Brianna; Whiteley, Aaron T.; Keszei, Alexander F.A.; +12 more

Effector-mediated membrane disruption controls cell death in CBASS antiphage defense

Citation Formats

References (42)

Similar Records

Related Subjects