A Genetic Map of the Response to DNA Damage in Human Cells
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July 2020 |
RNA m6A methylation regulates the ultraviolet-induced DNA damage response
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March 2017 |
METTL3 and N6-Methyladenosine Promote Homologous Recombination-Mediated Repair of DSBs by Modulating DNA-RNA Hybrid Accumulation
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August 2020 |
RNA modifications: what have we learned and where are we headed?
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May 2016 |
RNA modifications modulate gene expression during development
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September 2018 |
N 6 -methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription
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January 2020 |
Comparison of methylated sequences in messenger RNA and heterogeneous nuclear RNA from mouse L cells
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October 1977 |
DNA double-strand break repair-pathway choice in somatic mammalian cells
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July 2019 |
Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control
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November 2017 |
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis
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October 2019 |
N6-Methyladenosine co-transcriptionally directs the demethylation of histone H3K9me2
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August 2020 |
METTL3 regulates heterochromatin in mouse embryonic stem cells
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January 2021 |
The RNA m6A reader YTHDC1 silences retrotransposons and guards ES cell identity
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March 2021 |
Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally
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March 2019 |
An all-to-all approach to the identification of sequence-specific readers for epigenetic DNA modifications on cytosine
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February 2021 |
m6A RNA methylation regulates the fate of endogenous retroviruses
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January 2021 |
m 6 A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation
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January 2015 |
Transcription of IAP endogenous retroviruses is constrained by cytosine methylation
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October 1998 |
KAP1 controls endogenous retroviruses in embryonic stem cells
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January 2010 |
Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET
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February 2010 |
Epigenetic inheritance at the agouti locus in the mouse
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November 1999 |
Immunochemical evidence for the presence of 5mC, 6mA and 7mG in human, Drosophila and mealybug DNA
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July 1983 |
DNA methylation on N6-adenine in mammalian embryonic stem cells
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March 2016 |
N-methyladenine DNA Modification in Glioblastoma
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November 2018 |
N6-methyladenine in DNA antagonizes SATB1 in early development
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July 2020 |
Permanganate/S1 Nuclease Footprinting Reveals Non-B DNA Structures with Regulatory Potential across a Mammalian Genome
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March 2017 |
Quantitative LC-MS Provides No Evidence for m 6 dA or m 4 dC in the Genome of Mouse Embryonic Stem Cells and Tissues
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March 2017 |
No evidence for DNA N 6 -methyladenine in mammals
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March 2020 |
The origin of genomic N6-methyl-deoxyadenosine in mammalian cells
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March 2020 |
Peaking at the right time
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August 2020 |
Altered DNA base could play key role in pregnancy
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July 2020 |
The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond
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July 2015 |
The structure of APOBEC1 and insights into its RNA and DNA substrate selectivity
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October 2020 |
Tet2 promotes pathogen infection-induced myelopoiesis through mRNA oxidation
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January 2018 |
Functional role of Tet-mediated RNA hydroxymethylcytosine in mouse ES cells and during differentiation
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October 2020 |
Human MettL3–MettL14 complex is a sequence-specific DNA adenine methyltransferase active on single-strand and unpaired DNA in vitro
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December 2019 |
Nucleotide Excision Repair in Eukaryotes
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October 2013 |
The Carboxy-Terminal Domain of ROS1 Is Essential for 5-Methylcytosine DNA Glycosylase Activity
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November 2014 |
Biochemical and structural basis for YTH domain of human YTHDC1 binding to methylated adenine in DNA
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July 2020 |
Methyltransferase-Glo: a universal, bioluminescent and homogenous assay for monitoring all classes of methyltransferases
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March 2016 |
Multiparametric scaling of diffraction intensities
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April 2003 |
Phaser crystallographic software
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July 2007 |
Use of knowledge-based restraints in phenix.refine to improve macromolecular refinement at low resolution
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March 2012 |
Coot model-building tools for molecular graphics
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November 2004 |
A New Generation of Crystallographic Validation Tools for the Protein Data Bank
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October 2011 |
Formation of Cyclopyrimidines Via the Direct Effects of Gamma Radiation of Pyrimidine Nucleosides
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January 1988 |
Thymine Dimer-Induced Structural Changes to the DNA Duplex Examined with Reactive Probes
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November 2008 |
Base Pair Opening in a Deoxynucleotide Duplex Containing a cis-syn Thymine Cyclobutane Dimer Lesion
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December 2013 |
Influence of a cis,syn-cyclobutane pyrimidine dimer damage on DNA conformation studied by molecular dynamics simulations: cis,syn-Cyclobutane Pyrimidine Dimer Damage on DNA Conformation
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January 2015 |
Chromosomal landscape of UV damage formation and repair at single-nucleotide resolution
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July 2016 |
ETS transcription factors induce a unique UV damage signature that drives recurrent mutagenesis in melanoma
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July 2018 |
Elevated pyrimidine dimer formation at distinct genomic bases underlies promoter mutation hotspots in UV-exposed cancers
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December 2018 |
International Cancer Genome Consortium Data Portal--a one-stop shop for cancer genomics data
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January 2011 |
Intragenomic variability and extended sequence patterns in the mutational signature of ultraviolet light
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September 2019 |
TERT Promoter Mutations in Familial and Sporadic Melanoma
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journal
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January 2013 |
Highly Recurrent TERT Promoter Mutations in Human Melanoma
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January 2013 |
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
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March 2013 |
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma
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October 2013 |
Frequency of TERT promoter mutations in primary tumors of the liver
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September 2014 |
TERT promoter mutations and monoallelic activation of TERT in cancer
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December 2015 |
Telomerase reverse transcriptase promoter mutations in thyroid carcinomas: implications in precision oncology—a narrative review
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October 2020 |
New somatic TERT promoter variants enhance the Telomerase activity in Glioblastoma
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August 2020 |
TERT promoter mutations are associated with poor prognosis and cell immortalization in meningioma
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July 2018 |
TERT promoter mutations and telomeres during tumorigenesis
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February 2020 |
Chemical excitation of electrons: A dark path to melanoma
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August 2016 |
Chemiexcitation and Its Implications for Disease
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June 2018 |
Role of Melanin Chemiexcitation in Melanoma Progression and Drug Resistance
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August 2020 |
The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site
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October 2019 |
New insights into abasic site repair and tolerance
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June 2020 |
Sequencing abasic sites in DNA at single-nucleotide resolution
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June 2019 |
Apurinic/Apyrimidinic Endonuclease 1 Is the Essential Nuclease during Immunoglobulin Class Switch Recombination
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journal
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February 2013 |
Three DNA Polymerases, Recruited by Different Mechanisms, Carry Out NER Repair Synthesis in Human Cells
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March 2010 |
Evolutionary conservation of residues in vertebrate DNA polymerase N conferring low fidelity and bypass activity
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February 2010 |
Mechanism of somatic hypermutation at the WA motif by human DNA polymerase
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April 2013 |
How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis
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March 2015 |
The nucleotide pool is a significant target for oxidative stress
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August 2006 |
Incorporation of the Guanosine Triphosphate Analogs 8-Oxo-dGTP and 8-NH2-dGTP by Reverse Transcriptases and Mammalian DNA Polymerases
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February 1997 |
Incorporation and Replication of 8-Oxo-deoxyguanosine by the Human Mitochondrial DNA Polymerase
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November 2006 |
Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase replication fidelity
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February 2008 |
Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide
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November 2014 |
The m 6 A methylation perturbs the Hoogsteen pairing-guided incorporation of an oxidized nucleotide
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January 2017 |
The Mammalian Mismatch Repair Pathway Removes DNA 8-oxodGMP Incorporated from the Oxidized dNTP Pool
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June 2002 |
MSH2 and MSH6 Are Required for Removal of Adenine Misincorporated Opposite 8-Oxo-Guanine in S. cerevisiae
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September 1999 |
An 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase
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October 2009 |
Interactions among the Escherichia coli mutT, mutM, and mutY damage prevention pathways
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journal
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February 2003 |
A functional analysis of the DNA glycosylase activity of mouse MUTYH protein excising 2-hydroxyadenine opposite guanine in DNA
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January 2005 |
A Role for N6-Methyladenine in DNA Damage Repair
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journal
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March 2021 |
Reading m6A in the Transcriptome: m6A-Binding Proteins
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journal
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February 2018 |
Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain
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journal
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September 2014 |
Identification of YTH Domain-Containing Proteins as the Readers for N 1-Methyladenosine in RNA
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journal
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April 2018 |
Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA
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journal
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December 2015 |
Human Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 Superfamily
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journal
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April 2011 |
Holliday junction-resolving enzymes-structures and mechanisms
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journal
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January 2017 |
Structure and mechanism of pyrimidine–pyrimidone (6-4) photoproduct recognition by the Rad4/XPC nucleotide excision repair complex
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May 2019 |
Mammalian ALKBH1 serves as an N6-mA demethylase of unpairing DNA
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February 2020 |
EFFECTS OF HIGH LEVELS OF DNA ADENINE METHYLATION ON METHYL-DIRECTED MISMATCH REPAIR IN ESCHERICHIA COLI
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August 1983 |