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Knowledge-Based Design of 5-Fluororacil Prodrug Liposomal Formulation: Molecular Packing and Interac

Journal Article · · Mol. Pharmaceutics
Research Organization:
Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)
Sponsoring Organization:
DOE - Office Of Science; INDUSTRY; NSF
DOE Contract Number:
NONE;
OSTI ID:
1836730
Journal Information:
Mol. Pharmaceutics, Journal Name: Mol. Pharmaceutics Journal Issue: (12) Vol. 18
Country of Publication:
United States
Language:
ENGLISH

References (29)

Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue journal July 1998
Non-viral COVID-19 vaccine delivery systems journal February 2021
α,α′-trehalose 6,6′-dibehenate in non-phospholipid-based liposomes enables direct interaction with trehalose, offering stability during freeze-drying journal May 2008
Hydrophobic interactions modulate antimicrobial peptoid selectivity towards anionic lipid membranes journal June 2018
Lamellar crystalline self-assembly behaviour and solid lipid nanoparticles of a palmityl prodrug analogue of Capecitabine—A chemotherapy agent journal July 2011
Spontaneous collapse of palmitic acid films on an alkaline buffer containing calcium ions journal September 2020
Doxil® — The first FDA-approved nano-drug: Lessons learned journal June 2012
Synergistic antitumor activity of a self-assembling camptothecin and capecitabine hybrid prodrug for improved efficacy journal October 2017
Role of nanotechnology behind the success of mRNA vaccines for COVID-19 journal June 2021
Impeded Molecular Reorganization by Polyethylene Glycol Conjugation Revealed by X-ray Reflectivity and Diffraction Measurements journal June 2020
Polyunsaturated Phospholipid Modified Membrane Degradation Catalyzed by a Secreted Phospholipase A2 journal August 2019
The Catalytic Mechanism of Carboxylesterases: A Computational Study journal September 2014
Bilayer and Trilayer Crystalline Formation by Collapsing Behenic Acid Monolayers at Gas/Aqueous Interfaces journal January 2008
A Novel Mechanism Is Involved in Cationic Lipid-Mediated Functional siRNA Delivery journal March 2009
Phenylboronic Acid-Installed Polycarbonates for the pH-Dependent Release of Diol-Containing Molecules journal November 2014
Pegylated liposomal doxorubicin (doxil): Reduced clinical cardiotoxicity in patients reaching or exceeding cumulative doses of 500 mg/m2 journal August 2000
Nanostructured nanoparticles of self-assembled lipid pro-drugs as a route to improved chemotherapeutic agents journal January 2011
Co-delivery of small interfering RNA using a camptothecin prodrug as the carrier journal January 2014
Molecular interactions of phospholipid monolayers with a model phospholipase journal January 2019
Capecitabine as Adjuvant Treatment for Stage III Colon Cancer journal June 2005
Reduced cardiotoxicity and comparable efficacy in a phase IIItrial of pegylated liposomal doxorubicin HCl(CAELYX™/Doxil®) versus conventional doxorubicin forfirst-line treatment of metastatic breast cancer journal March 2004
Surface Studies of Solids by Total Reflection of X-Rays journal July 1954
Ordering in Lipid Monolayers Studied by Synchrotron X-Ray Diffraction and Fluorescence Microscopy journal May 1987
X-Ray Diffraction Studies of Organic Monolayers on the Surface of Water journal May 1987
High-loading Gα 13 -binding EXE peptide nanoparticles prevent thrombosis and protect mice from cardiac ischemia/reperfusion injury journal July 2020
Cholesterol-Peptide Hybrids to Form Liposome-Like Vesicles for Gene Delivery journal January 2013
Clinical Pharmacokinetics of Capecitabine journal January 2001
Capecitabine: A Review of its Pharmacology and Therapeutic Efficacy in the Management of Advanced Breast Cancer journal January 2003
Exploring the Correlation Between Lipid Packaging in Lipoplexes and Their Transfection Efficacy journal November 2011

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