Identification and Structure of a Multidonor Class of Head-Directed Influenza-Neutralizing Antibodie

Cheung, Crystal Sao-Fong; Fruehwirth, Alexander; Paparoditis, Philipp Carl Georg; Shen, Chen-Hsiang; Foglierini, Mathilde; Joyce, M. Gordon; Leung, Kwanyee; Piccoli, Luca; Rawi, Reda; Silacci-Fregni, Chiara; Tsybovsky, Yaroslav; Verardi, Raffaello; Wang, Lingshu; Wang, Shuishu; Yang, Eun Sung; Zhang, Baoshan; Zhang, Yi; Chuang, Gwo-Yu; Corti, Davide; Mascola, John R.; Shapiro, Lawrence; Kwong, Peter D.; Lanzavecchia, Antonio; Zhou, Tongqing

doi:10.1016/j.celrep.2020.108088

Title: Identification and Structure of a Multidonor Class of Head-Directed Influenza-Neutralizing Antibodie

Journal Article · Tue Sep 01 00:00:00 EDT 2020 · Cell Reports

DOI:https://doi.org/10.1016/j.celrep.2020.108088· OSTI ID:1834883

Cheung, Crystal Sao-Fong; Fruehwirth, Alexander; Paparoditis, Philipp Carl Georg; Shen, Chen-Hsiang; Foglierini, Mathilde; Joyce, M. Gordon; Leung, Kwanyee; Piccoli, Luca; Rawi, Reda; Silacci-Fregni, Chiara; Tsybovsky, Yaroslav; Verardi, Raffaello; Wang, Lingshu; Wang, Shuishu; Yang, Eun Sung; Zhang, Baoshan; Zhang, Yi; Chuang, Gwo-Yu; Corti, Davide; Mascola, John R. more »

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Research Organization:: Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)

Sponsoring Organization:: DOE - Office Of Science; FOREIGN; National Institutes of Health (NIH)

OSTI ID:: 1834883

Journal Information:: Cell Reports, Vol. 32, Issue (9)

Country of Publication:: United States

Language:: ENGLISH

References (59)

Recent developments in the PHENIX software for automated crystallographic structure determination Adams, Paul D.; Gopal, Kreshna; Grosse-Kunstleve, Ralf W. Journal of Synchrotron Radiation, Vol. 11, Issue 1 https://doi.org/10.1107/S0909049503024130	journal	November 2003
PHENIX: a comprehensive Python-based system for macromolecular structure solution Adams, Paul D.; Afonine, Pavel V.; Bunkóczi, Gábor Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 2, p. 213-221 https://doi.org/10.1107/S0907444909052925	journal	January 2010
Antibody Immunodominance: The Key to Understanding Influenza Virus Antigenic Drift Altman, Meghan O.; Angeletti, Davide; Yewdell, Jonathan W. Viral Immunology, Vol. 31, Issue 2 https://doi.org/10.1089/vim.2017.0129	journal	March 2018
Preferential induction of cross-group influenza A hemagglutinin stem–specific memory B cells after H7N9 immunization in humans Andrews, Sarah F.; Joyce, M. Gordon; Chambers, Michael J. Science Immunology, Vol. 2, Issue 13 https://doi.org/10.1126/sciimmunol.aan2676	journal	July 2017
Molecular Signatures of Hemagglutinin Stem-Directed Heterosubtypic Human Neutralizing Antibodies against Influenza A Viruses Avnir, Yuval; Tallarico, Aimee S.; Zhu, Quan PLoS Pathogens, Vol. 10, Issue 5 https://doi.org/10.1371/journal.ppat.1004103	journal	May 2014
A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface Bangaru, Sandhya; Lang, Shanshan; Schotsaert, Michael Cell, Vol. 177, Issue 5 https://doi.org/10.1016/j.cell.2019.04.011	journal	May 2019
Commonality despite exceptional diversity in the baseline human antibody repertoire Briney, Bryan; Inderbitzin, Anne; Joyce, Collin Nature, Vol. 566, Issue 7744 https://doi.org/10.1038/s41586-019-0879-y	journal	January 2019
Human Neutralizing Monoclonal Antibody Inhibition of Middle East Respiratory Syndrome Coronavirus Replication in the Common Marmoset Chen, Zhe; Bao, Linlin; Chen, Cong The Journal of Infectious Diseases, Vol. 215, Issue 12 https://doi.org/10.1093/infdis/jix209	journal	May 2017
Longitudinal analysis of the peripheral B cell repertoire reveals unique effects of immunization with a new influenza virus strain Cortina-Ceballos, Bernardo; Godoy-Lozano, Elizabeth Ernestina; Téllez-Sosa, Juan Genome Medicine, Vol. 7, Issue 1 https://doi.org/10.1186/s13073-015-0239-y	journal	November 2015
MOLPROBITY: structure validation and all-atom contact analysis for nucleic acids and their complexes Davis, I. W.; Murray, L. W.; Richardson, J. S. Nucleic Acids Research, Vol. 32, Issue Web Server https://doi.org/10.1093/nar/gkh398	journal	July 2004
The bulky and the sweet: How neutralizing antibodies and glycan receptors compete for virus binding: Virus-Glycan Interaction Blockade by Antibodies Dietrich, Melanie H.; Harprecht, Christina; Stehle, Thilo Protein Science, Vol. 26, Issue 12 https://doi.org/10.1002/pro.3319	journal	October 2017
Highly Conserved Protective Epitopes on Influenza B Viruses Dreyfus, C.; Laursen, N. S.; Kwaks, T. Science, Vol. 337, Issue 6100 https://doi.org/10.1126/science.1222908	journal	August 2012
Antibody Recognition of a Highly Conserved Influenza Virus Epitope Ekiert, D. C.; Bhabha, G.; Elsliger, M. -A. Science, Vol. 324, Issue 5924 https://doi.org/10.1126/science.1171491	journal	April 2009
Cross-neutralization of influenza A viruses mediated by a single antibody loop Ekiert, Damian C.; Kashyap, Arun K.; Steel, John Nature, Vol. 489, Issue 7417 https://doi.org/10.1038/nature11414	journal	September 2012
Coot model-building tools for molecular graphics Emsley, Paul; Cowtan, Kevin Acta Crystallographica Section D Biological Crystallography, Vol. 60, Issue 12, p. 2126-2132 https://doi.org/10.1107/S0907444904019158	journal	November 2004
Antigen distortion allows influenza virus to escape neutralization Fleury, Damien; Wharton, Steve A.; Skehel, John J. Nature Structural Biology, Vol. 5, Issue 2 https://doi.org/10.1038/nsb0298-119	journal	February 1998
CD-HIT: accelerated for clustering the next-generation sequencing data Fu, Limin; Niu, Beifang; Zhu, Zhengwei Bioinformatics, Vol. 28, Issue 23 https://doi.org/10.1093/bioinformatics/bts565	journal	October 2012
Investigating the effect of AS03 adjuvant on the plasma cell repertoire following pH1N1 influenza vaccination Galson, J. D.; Trück, J.; Kelly, D. F. Scientific Reports, Vol. 6, Issue 1 https://doi.org/10.1038/srep37229	journal	November 2016
Seasonal and pandemic influenza: global fatigue versus global preparedness Gilbert, Judith A. The Lancet Respiratory Medicine, Vol. 6, Issue 2 https://doi.org/10.1016/S2213-2600(17)30466-6	journal	February 2018
Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site Hong, M.; Lee, P. S.; Hoffman, R. M. B. Journal of Virology, Vol. 87, Issue 22 https://doi.org/10.1128/JVI.01388-13	journal	September 2013
Structure–function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans Huang, Kuan-Ying A.; Rijal, Pramila; Jiang, Haihai Nature Microbiology, Vol. 4, Issue 2 https://doi.org/10.1038/s41564-018-0303-7	journal	November 2018
Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses Joyce, M. Gordon; Wheatley, Adam K.; Thomas, Paul V. Cell, Vol. 166, Issue 3 https://doi.org/10.1016/j.cell.2016.06.043	journal	July 2016
Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes Kallewaard, Nicole L.; Corti, Davide; Collins, Patrick J. Cell, Vol. 166, Issue 3 https://doi.org/10.1016/j.cell.2016.05.073	journal	July 2016
Protection from the 2009 H1N1 Pandemic Influenza by an Antibody from Combinatorial Survivor-Based Libraries Kashyap, Arun K.; Steel, John; Rubrum, Adam PLoS Pathogens, Vol. 6, Issue 7 https://doi.org/10.1371/journal.ppat.1000990	journal	July 2010
Inference of Macromolecular Assemblies from Crystalline State Krissinel, Evgeny; Henrick, Kim Journal of Molecular Biology, Vol. 372, Issue 3 https://doi.org/10.1016/j.jmb.2007.05.022	journal	September 2007
Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody Kwon, Young D.; Chuang, Gwo-Yu; Zhang, Baoshan Cell Reports, Vol. 22, Issue 7 https://doi.org/10.1016/j.celrep.2018.01.023	journal	February 2018
HIV-1 Vaccines Based on Antibody Identification, B Cell Ontogeny, and Epitope Structure Kwong, Peter D.; Mascola, John R. Immunity, Vol. 48, Issue 5 https://doi.org/10.1016/j.immuni.2018.04.029	journal	May 2018
Antibody 27F3 Broadly Targets Influenza A Group 1 and 2 Hemagglutinins through a Further Variation in V H 1-69 Antibody Orientation on the HA Stem Lang, Shanshan; Xie, Jia; Zhu, Xueyong Cell Reports, Vol. 20, Issue 12 https://doi.org/10.1016/j.celrep.2017.08.084	journal	September 2017
Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity Lee, P. S.; Yoshida, R.; Ekiert, D. C. Proceedings of the National Academy of Sciences, Vol. 109, Issue 42 https://doi.org/10.1073/pnas.1212371109	journal	October 2012
IMGT®, the international ImMunoGeneTics information system® 25 years on Lefranc, Marie-Paule; Giudicelli, Véronique; Duroux, Patrice Nucleic Acids Research, Vol. 43, Issue D1 https://doi.org/10.1093/nar/gku1056	journal	November 2014
Structural and genetic basis for development of broadly neutralizing influenza antibodies Lingwood, Daniel; McTamney, Patrick M.; Yassine, Hadi M. Nature, Vol. 489, Issue 7417 https://doi.org/10.1038/nature11371	journal	August 2012
CryoEM Structure of an Influenza Virus Receptor-Binding Site Antibody–Antigen Interface Liu, Yuhang; Pan, Junhua; Jenni, Simon Journal of Molecular Biology, Vol. 429, Issue 12 https://doi.org/10.1016/j.jmb.2017.05.011	journal	June 2017
PIGS: automatic prediction of antibody structures Marcatili, P.; Rosi, A.; Tramontano, A. Bioinformatics, Vol. 24, Issue 17 https://doi.org/10.1093/bioinformatics/btn341	journal	July 2008
High-throughput immune repertoire analysis with IGoR Marcou, Quentin; Mora, Thierry; Walczak, Aleksandra M. Nature Communications, Vol. 9, Issue 1 https://doi.org/10.1038/s41467-018-02832-w	journal	February 2018
Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine Matsuda, Kenta; Huang, Jinghe; Zhou, Tongqing Science Immunology, Vol. 4, Issue 34 https://doi.org/10.1126/sciimmunol.aau2710	journal	April 2019
Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires McCarthy, Kevin R.; Watanabe, Akiko; Kuraoka, Masayuki Immunity, Vol. 48, Issue 1 https://doi.org/10.1016/j.immuni.2017.12.009	journal	January 2018
[20] Processing of X-ray diffraction data collected in oscillation mode Otwinowski, Zbyszek; Minor, Wladek Macromolecular Crystallography Part A, 307-326 https://doi.org/10.1016/S0076-6879(97)76066-X	book	January 1997
Rapid development of broadly influenza neutralizing antibodies through redundant mutations Pappas, Leontios; Foglierini, Mathilde; Piccoli, Luca Nature, Vol. 516, Issue 7531 https://doi.org/10.1038/nature13764	journal	October 2014
Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain Raymond, Donald D.; Stewart, Shaun M.; Lee, Jiwon Nature Medicine, Vol. 22, Issue 12 https://doi.org/10.1038/nm.4223	journal	November 2016
Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody Raymond, Donald D.; Bajic, Goran; Ferdman, Jack Proceedings of the National Academy of Sciences, Vol. 115, Issue 1 https://doi.org/10.1073/pnas.1715471115	journal	December 2017
Towards a universal influenza vaccine: different approaches for one goal Sautto, Giuseppe A.; Kirchenbaum, Greg A.; Ross, Ted M. Virology Journal, Vol. 15, Issue 1 https://doi.org/10.1186/s12985-017-0918-y	journal	January 2018
RELION: Implementation of a Bayesian approach to cryo-EM structure determination Scheres, Sjors H. W. Journal of Structural Biology, Vol. 180, Issue 3, p. 519-530 https://doi.org/10.1016/j.jsb.2012.09.006	journal	December 2012
Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody Schmidt, A. G.; Xu, H.; Khan, A. R. Proceedings of the National Academy of Sciences, Vol. 110, Issue 1 https://doi.org/10.1073/pnas.1218256109	journal	November 2012
Viral Receptor-Binding Site Antibodies with Diverse Germline Origins Schmidt, Aaron G.; Therkelsen, Matthew D.; Stewart, Shaun Cell, Vol. 161, Issue 5 https://doi.org/10.1016/j.cell.2015.04.028	journal	May 2015
OLGA: fast computation of generation probabilities of B- and T-cell receptor amino acid sequences and motifs Sethna, Zachary; Elhanati, Yuval; Callan, Curtis G. Bioinformatics, Vol. 35, Issue 17 https://doi.org/10.1093/bioinformatics/btz035	journal	January 2019
Molecular basis of the structure and function of H1 hemagglutinin of influenza virus Sriwilaijaroen, Nongluk; Suzuki, Yasuo Proceedings of the Japan Academy, Series B, Vol. 88, Issue 6 https://doi.org/10.2183/pjab.88.226	journal	January 2012
Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses Sui, Jianhua; Hwang, William C.; Perez, Sandra Nature Structural & Molecular Biology, Vol. 16, Issue 3 https://doi.org/10.1038/nsmb.1566	journal	February 2009
Heterosubtypic Neutralizing Monoclonal Antibodies Cross-Protective against H5N1 and H1N1 Recovered from Human IgM+ Memory B Cells Throsby, Mark; van den Brink, Edward; Jongeneelen, Mandy PLoS ONE, Vol. 3, Issue 12 https://doi.org/10.1371/journal.pone.0003942	journal	December 2008
Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning Tiller, Thomas; Meffre, Eric; Yurasov, Sergey Journal of Immunological Methods, Vol. 329, Issue 1-2 https://doi.org/10.1016/j.jim.2007.09.017	journal	January 2008
An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus Traggiai, Elisabetta; Becker, Stephan; Subbarao, Kanta Nature Medicine, Vol. 10, Issue 8 https://doi.org/10.1038/nm1080	journal	July 2004
Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses Tsibane, Tshidi; Ekiert, Damian C.; Krause, Jens C. PLoS Pathogens, Vol. 8, Issue 12 https://doi.org/10.1371/journal.ppat.1003067	journal	December 2012
Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin Whittle, J. R. R.; Zhang, R.; Khurana, S. Proceedings of the National Academy of Sciences, Vol. 108, Issue 34 https://doi.org/10.1073/pnas.1111497108	journal	August 2011
Flow Cytometry Reveals that H5N1 Vaccination Elicits Cross-Reactive Stem-Directed Antibodies from Multiple Ig Heavy-Chain Lineages Whittle, J. R. R.; Wheatley, A. K.; Wu, L. Journal of Virology, Vol. 88, Issue 8 https://doi.org/10.1128/JVI.03422-13	journal	February 2014
An Analysis of the Sequences of the Variable Regions of Bence Jones Proteins and Myeloma Light Chains and Their Implications for Antibody Complementarity Wu, T. T. Journal of Experimental Medicine, Vol. 132, Issue 2 https://doi.org/10.1084/jem.132.2.211	journal	August 1970
Structural Characterization of the Hemagglutinin Receptor Specificity from the 2009 H1N1 Influenza Pandemic Xu, R.; McBride, R.; Nycholat, C. M. Journal of Virology, Vol. 86, Issue 2 https://doi.org/10.1128/JVI.06322-11	journal	November 2011
A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin Xu, Rui; Krause, Jens C.; McBride, Ryan Nature Structural & Molecular Biology, Vol. 20, Issue 3 https://doi.org/10.1038/nsmb.2500	journal	February 2013
pH-Dependent Entry of Severe Acute Respiratory Syndrome Coronavirus Is Mediated by the Spike Glycoprotein and Enhanced by Dendritic Cell Transfer through DC-SIGN Yang, Zhi-Yong; Huang, Yue; Ganesh, Lakshmanan Journal of Virology, Vol. 78, Issue 11 https://doi.org/10.1128/JVI.78.11.5642-5650.2004	journal	June 2004
Structure and Receptor binding properties of a pandemic H1N1 virus hemagglutinin Yang, Hua; Carney, Paul; Stevens, James PLoS Currents, Vol. 2 https://doi.org/10.1371/currents.RRN1152	journal	March 2010
IgBLAST: an immunoglobulin variable domain sequence analysis tool Ye, Jian; Ma, Ning; Madden, Thomas L. Nucleic Acids Research, Vol. 41, Issue W1 https://doi.org/10.1093/nar/gkt382	journal	May 2013

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