PHENIX: a comprehensive Python-based system for macromolecular structure solution
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January 2010 |
Prevention of tau seeding and propagation by immunotherapy with a central tau epitope antibody
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April 2019 |
Tau and tauopathies
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September 2016 |
Differential Mass Spectrometry Profiles of Tau Protein in the Cerebrospinal Fluid of Patients with Alzheimer’s Disease, Progressive Supranuclear Palsy, and Dementia with Lewy Bodies
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April 2016 |
Disease-related Modifications in Tau Affect the Interaction between Fyn and Tau
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October 2005 |
Tyrosine phosphorylation of tau accompanies disease progression in transgenic mouse models of tauopathy: Tyrosine-phosphorylated tau in mouse models
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June 2010 |
The Dynamic Structure of Filamentous Tau
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October 2011 |
Advances in progressive supranuclear palsy: new diagnostic criteria, biomarkers, and therapeutic approaches
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July 2017 |
Safety of the tau-directed monoclonal antibody BIIB092 in progressive supranuclear palsy: a randomised, placebo-controlled, multiple ascending dose phase 1b trial
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June 2019 |
Human secreted tau increases amyloid-beta production
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February 2015 |
Learnings about the complexity of extracellular tau aid development of a blood‐based screen for Alzheimer's disease
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November 2018 |
Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer’s disease
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December 2018 |
From the prion-like propagation hypothesis to therapeutic strategies of anti-tau immunotherapy
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November 2019 |
Tau burden and the functional connectome in Alzheimer’s disease and progressive supranuclear palsy
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January 2018 |
Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau
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September 2018 |
BIN1 favors the spreading of Tau via extracellular vesicles
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July 2019 |
Compound screening in cell-based models of tau inclusion formation: Comparison of primary neuron and HEK293 cell assays
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March 2020 |
Tau Passive Immunotherapy in Mutant P301L Mice: Antibody Affinity versus Specificity
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April 2013 |
β-Sheet Core of Tau Paired Helical Filaments Revealed by Solid-State NMR
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August 2012 |
In vitro 0N4R tau fibrils contain a monomorphic β-sheet core enclosed by dynamically heterogeneous fuzzy coat segments
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July 2019 |
Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer’s Disease
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September 2018 |
Features and development of Coot
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March 2010 |
Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory
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January 2016 |
Structures of filaments from Pick’s disease reveal a novel tau protein fold
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August 2018 |
Cryo-EM structures of tau filaments from Alzheimer’s disease
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July 2017 |
Tau Spreading Mechanisms; Implications for Dysfunctional Tauopathies
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February 2018 |
Factors other than hTau overexpression that contribute to tauopathy-like phenotype in rTg4510 mice
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June 2019 |
Detection of Alzheimer Disease (AD)-Specific Tau Pathology in AD and NonAD Tauopathies by Immunohistochemistry With Novel Conformation-Selective Tau Antibodies
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February 2018 |
Mechanisms of Cell-to-Cell Transmission of Pathological Tau: A Review
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January 2019 |
Extracellular tau is toxic to neuronal cells
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August 2006 |
Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells
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April 2008 |
Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles
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February 2018 |
Unique pathological tau conformers from Alzheimer’s brains transmit tau pathology in nontransgenic mice
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October 2016 |
Roles of tau protein in health and disease
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April 2017 |
Introduction of Tau Oligomers into Cortical Neurons Alters Action Potential Dynamics and Disrupts Synaptic Transmission and Plasticity
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September 2019 |
Proteopathic tau seeding predicts tauopathy in vivo
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September 2014 |
A walk through tau therapeutic strategies
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February 2019 |
Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau
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April 1997 |
XDS
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January 2010 |
Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport
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April 2012 |
Extracellular Tau Levels Are Influenced by Variability in Tau That Is Associated with Tauopathies
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December 2012 |
Inference of Macromolecular Assemblies from Crystalline State
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September 2007 |
Shape complementarity and hydrogen bond preferences in protein–protein interfaces: implications for antibody modeling and protein–protein docking
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April 2016 |
Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau
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October 2012 |
Molecular biomarkers of Alzheimer's disease: progress and prospects
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May 2018 |
Shape Complementarity at Protein/Protein Interfaces
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December 1993 |
The interpretation of protein structures: Estimation of static accessibility
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February 1971 |
Phosphorylation of Tau by Fyn: Implications for Alzheimer's Disease
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March 2004 |
Characterization of Two VQIXXK Motifs for Tau Fibrillization in Vitro
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December 2006 |
Elucidating Tau function and dysfunction in the era of cryo-EM
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June 2019 |
Tau elevations in the brain extracellular space correlate with reduced amyloid-β levels and predict adverse clinical outcomes after severe traumatic brain injury
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November 2011 |
Loss of Tau protein affects the structure, transcription and repair of neuronal pericentromeric heterochromatin
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September 2016 |
Phaser crystallographic software
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July 2007 |
Characterization of Novel CSF Tau and ptau Biomarkers for Alzheimer’s Disease
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October 2013 |
Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation
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February 2013 |
Tau Trimers Are the Minimal Propagation Unit Spontaneously Internalized to Seed Intracellular Aggregation
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June 2015 |
Phosphorylation of tau at Y18, but not tau-fyn binding, is required for tau to modulate NMDA receptor-dependent excitotoxicity in primary neuronal culture
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May 2017 |
Structural Polymorphism of 441-Residue Tau at Single Residue Resolution
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February 2009 |
Pathological Tau Strains from Human Brains Recapitulate the Diversity of Tauopathies in Nontransgenic Mouse Brain
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October 2017 |
Phosphorylation of different tau sites during progression of Alzheimer’s disease
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June 2018 |
Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature
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May 2012 |
Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro
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June 2017 |
Ten Years of Tau-Targeted Immunotherapy: The Path Walked and the Roads Ahead
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November 2018 |
Physiological release of endogenous tau is stimulated by neuronal activity
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February 2013 |
A randomized, single ascending dose study of intravenous BIIB092 in healthy participants
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January 2018 |
Age-Dependent Neurofibrillary Tangle Formation, Neuron Loss, and Memory Impairment in a Mouse Model of Human Tauopathy (P301L)
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November 2005 |
A possible link between astrocyte activation and tau nitration in Alzheimer's disease
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August 2008 |
Selective tau tyrosine nitration in non-AD tauopathies
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November 2011 |
Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies
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June 2014 |
Passive Immunization with Phospho-Tau Antibodies Reduces Tau Pathology and Functional Deficits in Two Distinct Mouse Tauopathy Models
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May 2015 |
Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function
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July 2005 |
Tau Kinetics in Neurons and the Human Central Nervous System
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March 2018 |
Tyrosine Phosphorylation of Tau by the Src Family Kinases Lck and Fyn
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January 2011 |
Predictive Atomic Resolution Descriptions of Intrinsically Disordered hTau40 and α-Synuclein in Solution from NMR and Small Angle Scattering
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February 2014 |
CNS tau efflux via exosomes is likely increased in Parkinson's disease but not in Alzheimer's disease
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May 2016 |
Tau Immunotherapies for Alzheimer’s Disease and Related Tauopathies: Progress and Potential Pitfalls1
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June 2018 |
Cerebrospinal fluid from Alzheimer’s disease patients promotes tau aggregation in transgenic mice
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May 2019 |
Novel versatile cryoprotectants for heavy-atom derivatization of protein crystals
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April 2006 |
Seed‐competent high‐molecular‐weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients
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August 2016 |
Tyrosine phosphorylation of tau regulates its interactions with Fyn SH2 domains, but not SH3 domains, altering the cellular localization of tau: Tyrosine phosphorylation-dependent tau-Fyn binding
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July 2011 |
Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity
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May 2016 |
Divergent CSF alterations in two common tauopathies: Alzheimer's disease and progressive supranuclear palsy
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June 2014 |
Tau in physiology and pathology
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December 2015 |
Overview of the CCP 4 suite and current developments
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March 2011 |
Propagation of prions causing synucleinopathies in cultured cells
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August 2015 |
Neuronal activity enhances tau propagation and tau pathology in vivo
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June 2016 |
Extracellular Tau and Its Potential Role in the Propagation of Tau Pathology
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November 2017 |
In Vivo Microdialysis Reveals Age-Dependent Decrease of Brain Interstitial Fluid Tau Levels in P301S Human Tau Transgenic Mice
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September 2011 |
Neuronal activity regulates extracellular tau in vivo
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February 2014 |
Anti‐tau antibody reduces insoluble tau and decreases brain atrophy
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January 2015 |
Structural evaluations of tau protein conformation: methodologies and approaches
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June 2017 |
Novel tau filament fold in corticobasal degeneration
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February 2020 |