Overcoming GNA/RNA base-pairing limitations using isonucleotides improves the pharmacodynamic activi

Schlegel, Mark K.; Matsuda, Shigeo; Brown, Christopher R.; Harp, Joel M.; Barry, Joseph D.; Berman, Daniel; Castoreno, Adam; Schofield, Sally; Szeto, John; Manoharan, Muthiah; Charisse, Klaus; Egli, Martin; Maier, Martin A.

doi:10.1093/nar/gkab916

Overcoming GNA/RNA base-pairing limitations using isonucleotides improves the pharmacodynamic activi

Journal Article · 01 November 2021 · Nucleic Acids Res.

DOI:https://doi.org/10.1093/nar/gkab916· OSTI ID:1829881

Schlegel, Mark K.; Matsuda, Shigeo; Brown, Christopher R.; Harp, Joel M.; Barry, Joseph D.; Berman, Daniel; Castoreno, Adam; Schofield, Sally; Szeto, John; Manoharan, Muthiah; Charisse, Klaus; Egli, Martin; Maier, Martin A.

Research Organization:: Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)

Sponsoring Organization:: DOE - Office Of Science; INDUSTRY

OSTI ID:: 1829881

Journal Information:: Nucleic Acids Res., Vol. 49, Issue (19)

Country of Publication:: United States

Language:: ENGLISH

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