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Structural insights into hepatitis C virus receptor binding and entry

Journal Article · · Nature
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Research Organization:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
DOE - Office Of Science; National Institutes of Health (NIH)
OSTI ID:
1828931
Journal Information:
Nature, Vol. 598
Country of Publication:
United States
Language:
ENGLISH

References (38)

Hepatitis C Virus Entry: Protein Interactions and Fusion Determinants Governing Productive Hepatocyte Invasion August 2019
The Neutralizing Face of Hepatitis C Virus E2 Envelope Glycoprotein June 2018
Time- and Temperature-Dependent Activation of Hepatitis C Virus for Low-pH-Triggered Entry February 2006
Dissecting the role of putative CD81 binding regions of E2 in mediating HCV entry: Putative CD81 binding region 1 is not involved in CD81 binding January 2008
Identification of the Hepatitis C Virus E2 Glycoprotein Binding Site on the Large Extracellular Loop of CD81 November 2002
A Conserved Gly 436 -Trp-Leu-Ala-Gly-Leu-Phe-Tyr Motif in Hepatitis C Virus Glycoprotein E2 Is a Determinant of CD81 Binding and Viral Entry August 2006
Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding August 2006
A Neutralization Epitope in the Hepatitis C Virus E2 Glycoprotein Interacts with Host Entry Factor CD81 January 2014
Identification of Amino Acid Residues in CD81 Critical for Interaction with Hepatitis C Virus Envelope Glycoprotein E2 April 2000
Diverse CD81 Proteins Support Hepatitis C Virus Infection August 2006
Hepatitis C Virus Envelope Protein E2 Binds to CD81 of Tamarins November 2000
Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2 February 2014
CD81 extracellular domain 3D structure: insight into the tetraspanin superfamily structural motifs January 2001
Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop January 2017
Hepatitis C Virus Structure: Defined by What It Is Not September 2019
Cryo-EM structure of the B cell co-receptor CD19 bound to the tetraspanin CD81 January 2021
HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design November 2018
Hepatitis C Virus E2 Envelope Glycoprotein Core Structure November 2013
An ultralong CDRH2 in HCV neutralizing antibody demonstrates structural plasticity of antibodies against E2 glycoprotein March 2020
Genetic and structural insights into broad neutralization of hepatitis C virus by human V H 1-69 antibodies January 2019
Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket November 2016
Structural Basis of Ligand Interactions of the Large Extracellular Domain of Tetraspanin CD81 June 2012
Conformational Flexibility in the Immunoglobulin-Like Domain of the Hepatitis C Virus Glycoprotein E2 July 2017
OPM database and PPM web server: resources for positioning of proteins in membranes September 2011
Mechanisms of Virus Membrane Fusion Proteins November 2014
Distinct roles in folding, CD81 receptor binding and viral entry for conserved histidine residues of hepatitis C virus glycoprotein E1 and E2 March 2012
Hepatitis C Virus Is Primed by CD81 Protein for Low pH-dependent Fusion September 2011
Fusion of Enveloped Viruses in Endosomes: Virus Fusion in Endosomes April 2016
Mutagenesis of the fusion peptide-like domain of hepatitis C virus E1 glycoprotein: involvement in cell fusion and virus entry September 2009
PHENIX : building new software for automated crystallographic structure determination October 2002
Coot model-building tools for molecular graphics November 2004
Structural analysis of glycoproteins: building N-linked glycans with Coot April 2018
MolProbity : all-atom structure validation for macromolecular crystallography December 2009
The EMBL-EBI search and sequence analysis tools APIs in 2019 April 2019
Electrostatics of nanosystems: Application to microtubules and the ribosome August 2001
PDB2PQR: an automated pipeline for the setup of Poisson-Boltzmann electrostatics calculations July 2004
High-Precision Isothermal Titration Calorimetry with Automated Peak-Shape Analysis June 2012
SEDPHAT – A platform for global ITC analysis and global multi-method analysis of molecular interactions April 2015

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