Binding specificity and function of the SWI/SNF subunit SMARCA4 bromodomain interaction with acetyla

Enriquez, Paul; Krajewski, Krzysztof; Strahl, Brian D.; Rothbart, Scott B.; Dowen, Robert H.; Rose, Robert B.

doi:10.1016/j.jbc.2021.101145

Binding specificity and function of the SWI/SNF subunit SMARCA4 bromodomain interaction with acetyla

Journal Article · 01 October 2021 · J. Biol. Chem.

DOI:https://doi.org/10.1016/j.jbc.2021.101145· OSTI ID:1828038

Enriquez, Paul; Krajewski, Krzysztof; Strahl, Brian D.; Rothbart, Scott B.; Dowen, Robert H.; Rose, Robert B.

Research Organization:: Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)

Sponsoring Organization:: DOE - Office Of Science; National Institutes of Health (NIH)

OSTI ID:: 1828038

Journal Information:: J. Biol. Chem., Vol. 297, Issue (4)

Country of Publication:: United States

Language:: ENGLISH

References (72)

Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family No authors listed Cell https://doi.org/10.1016/j.cell.2012.02.013		March 2012
A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications No authors listed Structure https://doi.org/10.1016/j.str.2015.08.004		October 2015
The bromodomain: a conserved sequence found in human, Drosophila and yeast proteins No authors listed Nucleic Acids Research https://doi.org/10.1093/nar/20.10.2603		January 1992
brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2SWI2 No authors listed Cell https://doi.org/10.1016/0092-8674(92)90191-E		February 1992
Advancements in the Development of non‐BET Bromodomain Chemical Probes No authors listed ChemMedChem https://doi.org/10.1002/cmdc.201800738		January 2019
Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer No authors listed Nature https://doi.org/10.1038/s41586-020-1930-8		January 2020
Selective inhibition of BET bromodomains No authors listed Nature https://doi.org/10.1038/nature09504		September 2010
Small-Molecule Inhibition of BRDT for Male Contraception No authors listed Cell https://doi.org/10.1016/j.cell.2012.06.045		August 2012
Suppression of inflammation by a synthetic histone mimic No authors listed Nature https://doi.org/10.1038/nature09589		November 2010
Maintenance of MYC expression promotes de novo resistance to BET bromodomain inhibition in castration-resistant prostate cancer No authors listed Scientific Reports https://doi.org/10.1038/s41598-019-40518-5		March 2019
BET inhibitor resistance emerges from leukaemia stem cells No authors listed Nature https://doi.org/10.1038/nature14888		September 2015
Resistance to BET Inhibitor Leads to Alternative Therapeutic Vulnerabilities in Castration-Resistant Prostate Cancer No authors listed Cell Reports https://doi.org/10.1016/j.celrep.2018.02.011		February 2018
Transcriptional plasticity promotes primary and acquired resistance to BET inhibition No authors listed Nature https://doi.org/10.1038/nature14898		September 2015
Unwinding chromatin for development and growth: a few genes at a time No authors listed Trends in Genetics https://doi.org/10.1016/j.tig.2007.05.010		August 2007
The Swi/Snf family No authors listed Trends in Genetics https://doi.org/10.1016/S0168-9525(00)02060-6		August 2000
Octamer Transfer and Creation of Stably Remodeled Nucleosomes by Human SWI-SNF and Its Isolated ATPases No authors listed Molecular and Cellular Biology https://doi.org/10.1128/MCB.20.17.6380-6389.2000		September 2000
Reconstitution of a Core Chromatin Remodeling Complex from SWI/SNF Subunits No authors listed Molecular Cell https://doi.org/10.1016/S1097-2765(00)80315-9		February 1999
Requirement for SWI/SNF chromatin-remodeling complex in Tat-mediated activation of the HIV-1 promoter No authors listed The EMBO Journal https://doi.org/10.1038/sj.emboj.7601074		April 2006
DNA binding drives the association of BRG1/hBRM bromodomains with nucleosomes No authors listed Nature Communications https://doi.org/10.1038/ncomms16080		July 2017
BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription No authors listed Nature https://doi.org/10.1038/366170a0		November 1993
Frequent BRG1/SMARCA4-inactivating mutations in human lung cancer cell lines No authors listed Human Mutation https://doi.org/10.1002/humu.20730		April 2008
Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4 No authors listed Nature Genetics https://doi.org/10.1038/ng.2928		March 2014
Brahma-related gene 1 bridges epigenetic regulation of proinflammatory cytokine production to steatohepatitis in mice No authors listed Hepatology https://doi.org/10.1002/hep.26207		July 2013
Structure of nucleosome-bound human BAF complex No authors listed Science https://doi.org/10.1126/science.aaz9761		February 2020
Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure No authors listed Nature https://doi.org/10.1038/nature22036		April 2017
Solution Structure of Human Brg1 Bromodomain and Its Specific Binding to Acetylated Histone Tails ^, No authors listed Biochemistry https://doi.org/10.1021/bi0611208		February 2007
Structural Ramification for Acetyl-Lysine Recognition by the Bromodomain of Human BRG1 Protein, a Central ATPase of the SWI/SNF Remodeling Complex No authors listed ChemBioChem https://doi.org/10.1002/cbic.200600562		July 2007
Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance No authors listed Science Advances https://doi.org/10.1126/sciadv.1500723		November 2015
The Structural Basis for Specific Recognition of H3K14 Acetylation by Sth1 in the RSC Chromatin Remodeling Complex No authors listed Structure https://doi.org/10.1016/j.str.2019.10.015		January 2020
Taf14 recognizes a common motif in transcriptional machineries and facilitates their clustering by phase separation No authors listed Nature Communications https://doi.org/10.1038/s41467-020-18021-7		August 2020
Structure of the RSC complex bound to the nucleosome No authors listed Science https://doi.org/10.1126/science.aay0033		October 2019
Binding Hotspots of BAZ2B Bromodomain: Histone Interaction Revealed by Solution NMR Driven Docking No authors listed Biochemistry https://doi.org/10.1021/bi500909d		October 2014
Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery No authors listed Molecular BioSystems https://doi.org/10.1039/c1mb05099k		January 2011
Molecular Basis of Histone Tail Recognition by Human TIP5 PHD Finger and Bromodomain of the Chromatin Remodeling Complex NoRC No authors listed Structure https://doi.org/10.1016/j.str.2014.10.017		January 2015
The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase Gcn5p No authors listed The EMBO Journal https://doi.org/10.1093/emboj/19.22.6141		November 2000
Metabolic regulation of gene expression through histone acylations No authors listed Nature Reviews Molecular Cell Biology https://doi.org/10.1038/nrm.2016.140		December 2016
Automated electron-density sampling reveals widespread conformational polymorphism in proteins: Electron-density Sampling Detects Hidden Ensembles No authors listed Protein Science https://doi.org/10.1002/pro.423		May 2010
Multiple functions of PBRM-1/Polybromo- and LET-526/Osa-containing chromatin remodeling complexes in C. elegans development No authors listed Developmental Biology https://doi.org/10.1016/j.ydbio.2011.10.035		January 2012
High affinity binding of H3K14ac through collaboration of bromodomains 2, 4 and 5 is critical for the molecular and tumor suppressor functions of PBRM 1 No authors listed Molecular Oncology https://doi.org/10.1002/1878-0261.12434		February 2019
PBRM1 bromodomains variably influence nucleosome interactions and cellular function No authors listed Journal of Biological Chemistry https://doi.org/10.1074/jbc.RA118.003381		August 2018
Reversible acetylation of the chromatin remodelling complex NoRC is required for non-coding RNA-dependent silencing No authors listed Nature Cell Biology https://doi.org/10.1038/ncb1914		July 2009
Rapid and Precise Engineering of the Caenorhabditis elegans Genome with Lethal Mutation Co-Conversion and Inactivation of NHEJ Repair No authors listed Genetics https://doi.org/10.1534/genetics.114.172361		December 2014
Components of the SWI/SNF Complex Are Required for Asymmetric Cell Division in C. elegans No authors listed Molecular Cell https://doi.org/10.1016/S1097-2765(00)00060-5		September 2000
Caenorhabditis elegans SWI/SNF Subunits Control Sequential Developmental Stages in the Somatic Gonad No authors listed G3 Genes\|Genomes\|Genetics https://doi.org/10.1534/g3.113.009852		March 2014
SWI/SNF chromatin remodeling regulates alcohol response behaviors in Caenorhabditis elegans and is associated with alcohol dependence in humans No authors listed Proceedings of the National Academy of Sciences https://doi.org/10.1073/pnas.1413451112		February 2015
Chromatin-remodeling and the initiation of transcription No authors listed Quarterly Reviews of Biophysics https://doi.org/10.1017/S0033583515000116		July 2015
Rad4–Rad23 interaction with SWI/SNF links ATP-dependent chromatin remodeling with nucleotide excision repair No authors listed Nature Structural & Molecular Biology https://doi.org/10.1038/nsmb1152		October 2006
Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting γ-H2AX induction No authors listed The EMBO Journal https://doi.org/10.1038/sj.emboj.7601291		August 2006
BRG1 co-localizes with DNA replication factors and is required for efficient replication fork progression No authors listed Nucleic Acids Research https://doi.org/10.1093/nar/gkq559		June 2010
Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes No authors listed Cell https://doi.org/10.1016/j.cell.2018.09.032		November 2018
The SWI/SNF complex in cancer — biology, biomarkers and therapy No authors listed Nature Reviews Clinical Oncology https://doi.org/10.1038/s41571-020-0357-3		April 2020
Redundancy of Chromatin Remodeling Pathways for the Induction of the Yeast PHO5 Promoter in Vivo No authors listed Journal of Biological Chemistry https://doi.org/10.1074/jbc.M700623200		September 2007
Unique, Shared, and Redundant Roles for the Arabidopsis SWI/SNF Chromatin Remodeling ATPases BRAHMA and SPLAYED No authors listed The Plant Cell https://doi.org/10.1105/tpc.106.048272		February 2007
Structure and ligand of a histone acetyltransferase bromodomain No authors listed Nature https://doi.org/10.1038/20974		June 1999
Thermodynamic analysis of acetylation-dependent Pb1 bromodomain–histone H3 interactions No authors listed Analytical Biochemistry https://doi.org/10.1016/j.ab.2007.12.008		March 2008
Structural insights into selective histone H3 recognition by the human Polybromo bromodomain 2 No authors listed Cell Research https://doi.org/10.1038/cr.2010.43		April 2010
Polybromo-1-bromodomains bind histone H3 at specific acetyl-lysine positions No authors listed Biochemical and Biophysical Research Communications https://doi.org/10.1016/j.bbrc.2007.01.193		April 2007
Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis No authors listed Nature Communications https://doi.org/10.1038/s41467-017-02403-5		December 2017
Selective BET bromodomain inhibition as an antifungal therapeutic strategy No authors listed Nature Communications https://doi.org/10.1038/ncomms15482		May 2017
Defined PEG smears as an alternative approach to enhance the search for crystallization conditions and crystal-quality improvement in reduced screens No authors listed Acta Crystallographica Section D Biological Crystallography https://doi.org/10.1107/S1399004715007968		July 2015
[20] Processing of X-ray diffraction data collected in oscillation mode No authors listed Macromolecular Crystallography Part A https://doi.org/10.1016/S0076-6879(97)76066-X		January 1997
Phaser crystallographic software No authors listed Journal of Applied Crystallography https://doi.org/10.1107/S0021889807021206		July 2007
PHENIX: a comprehensive Python-based system for macromolecular structure solution No authors listed Acta Crystallographica Section D Biological Crystallography https://doi.org/10.1107/S0907444909052925		January 2010
Features and development of Coot No authors listed Acta Crystallographica Section D Biological Crystallography https://doi.org/10.1107/S0907444910007493		March 2010
Influence of Combinatorial Histone Modifications on Antibody and Effector Protein Recognition No authors listed Current Biology https://doi.org/10.1016/j.cub.2010.11.058		January 2011
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs No authors listed Nucleic Acids Research https://doi.org/10.1093/nar/25.17.3389		September 1997
BAli-Phy: simultaneous Bayesian inference of alignment and phylogeny No authors listed Bioinformatics https://doi.org/10.1093/bioinformatics/btl175		May 2006
Predicting functionally important residues from sequence conservation No authors listed Bioinformatics https://doi.org/10.1093/bioinformatics/btm270		May 2007
THE GENETICS OF CAENORHABDITIS ELEGANS No authors listed Genetics https://doi.org/10.1093/genetics/77.1.71		May 1974
A microRNA program in the C. elegans hypodermis couples to intestinal mTORC2/PQM-1 signaling to modulate fat transport No authors listed Genes & Development https://doi.org/10.1101/gad.283895.116		July 2016
CEH-60/PBX and UNC-62/MEIS Coordinate a Metabolic Switch that Supports Reproduction in C. elegans No authors listed Developmental Cell https://doi.org/10.1016/j.devcel.2019.03.002		April 2019
TRIM24 links a non-canonical histone signature to breast cancer No authors listed Nature https://doi.org/10.1038/nature09542		December 2010

Similar Records

HIC1 interacts with a specific subunit of SWI/SNF complexes, ARID1A/BAF250A

Journal Article · 2009 · Biochemical and Biophysical Research Communications · OSTI ID:22199757

Van Rechem, Capucine; Boulay, Gaylor; Leprince, Dominique

Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity

Journal Article · 2012 · Experimental Cell Research · OSTI ID:22212600

Kothandapani, Anbarasi; Gopalakrishnan, Kathirvel; Kahali, Bhaskar; +1 more

SRG3/mBAF155 stabilizes the SWI/SNF-like BAF complex by blocking CHFR mediated ubiquitination and degradation of its major components

Journal Article · 2012 · Biochemical and Biophysical Research Communications · OSTI ID:22207709

Jung, Inkyung; Sohn, Dong H.; Choi, Jinwook; +3 more

Binding specificity and function of the SWI/SNF subunit SMARCA4 bromodomain interaction with acetyla

Citation Formats

References (72)

Similar Records

Related Subjects