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Intravenous Delivery of Lung-Targeted Nanofibers for Pulmonary Hypertension in Mice

Journal Article · · Adv. Healthcare Mat.

Research Organization:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
DOE - Office Of Science; National Institutes of Health (NIH); UNIVERSITY
OSTI ID:
1818325
Journal Information:
Adv. Healthcare Mat., Vol. 10, Issue (13)
Country of Publication:
United States
Language:
ENGLISH

References (96)

Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives January 2019
Five-Year Outcomes of Patients Enrolled in the REVEAL Registry October 2015
A review of prostaglandin analogs in the management of patients with pulmonary arterial hypertension January 2010
Nanotherapeutics for Treatment of Pulmonary Arterial Hypertension July 2018
What’s in a side effect? The association between pulmonary vasodilator adverse drug events and clinical outcomes in patients with pulmonary arterial hypertension August 2017
Pharmacologic treatments for pulmonary hypertension: exploring pharmacogenomics May 2013
A meta-analysis of trials of pulmonary hypertension: A clinical condition looking for drugs and research methodology June 2007
Principles of nanoparticle design for overcoming biological barriers to drug delivery September 2015
Liposomal fasudil, a rho-kinase inhibitor, for prolonged pulmonary preferential vasodilation in pulmonary arterial hypertension April 2013
Lipid nanoparticle delivery of a microRNA-145 inhibitor improves experimental pulmonary hypertension July 2015
Targeted Delivery of Sildenafil for Inhibiting Pulmonary Vascular Remodeling March 2019
Nanoparticle-Mediated Targeting of Pitavastatin to Small Pulmonary Arteries and Leukocytes by Intravenous Administration Attenuates the Progression of Monocrotaline-Induced Established Pulmonary Arterial Hypertension in Rats January 2018
Rapamycin nanoparticles localize in diseased lung vasculature and prevent pulmonary arterial hypertension May 2017
Encapsulation of beraprost sodium in nanoparticles: Analysis of sustained release properties, targeting abilities and pharmacological activities in animal models of pulmonary arterial hypertension January 2015
Shape-Dependent Targeting of Injured Blood Vessels by Peptide Amphiphile Supramolecular Nanostructures February 2015
Mediating Tumor Targeting Efficiency of Nanoparticles Through Design May 2009
An Assessment of the Effects of Shell Cross-Linked Nanoparticle Size, Core Composition, and Surface PEGylation on in Vivo Biodistribution September 2005
Self-Assembly and Mineralization of Peptide-Amphiphile Nanofibers November 2001
Tissue-Factor Targeted Peptide Amphiphile Nanofibers as an Injectable Therapy To Control Hemorrhage December 2015
Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties November 2003
Self-assembled polypeptide-block-poly(vinylpyrrolidone) as prospective drug-delivery systems November 2009
Targeted Nitric Oxide Delivery by Supramolecular Nanofibers for the Prevention of Restenosis After Arterial Injury March 2016
Development of Optimized Tissue-Factor-Targeted Peptide Amphiphile Nanofibers to Slow Noncompressible Torso Hemorrhage May 2020
Expression of pulmonary vascular angiotensin-converting enzyme in primary and secondary plexiform pulmonary hypertension January 2000
Angiotensin converting enzyme expression is increased in small pulmonary arteries of rats with hypoxia-induced pulmonary hypertension. October 1995
Interaction of mAb to angiotensin-converting enzyme (ACE) with antigen in vitro and in vivo : antibody targeting to the lung induces ACE antigenic modulation January 1994
All the “RAGE” in lung disease: The receptor for advanced glycation endproducts (RAGE) is a major mediator of pulmonary inflammatory responses June 2017
RAGE-mediated extracellular matrix proteins accumulation exacerbates HySu-induced pulmonary hypertension April 2017
Angiotensin I-converting enzyme inhibitory peptides from Sipuncula (Phascolosoma esculenta): Purification, identification, molecular docking and antihypertensive effects on spontaneously hypertensive rats December 2017
Virtual screening for angiotensin I-converting enzyme inhibitory peptides from Phascolosoma esculenta October 2014
Haemodynamic and hormonal effects of captopril in primary pulmonary hypertension. December 1982
Right ventricular hypertrophy and apoptosis after pulmonary artery banding: regulation of PKC isozymes September 2003
Angiotensin-converting Enzyme Inhibition Delays Pulmonary Vascular Neointimal Formation September 1998
Captopril as treatment for patients with pulmonary hypertension. Problem of variability in assessing chronic drug treatment. September 1982
Captopril in primary pulmonary hypertension. January 1983
Inhibition Mechanism and Model of an Angiotensin I-Converting Enzyme (ACE)-Inhibitory Hexapeptide from Yeast (Saccharomyces cerevisiae) May 2012
Isolation and Identification of an Angiotensin-I Converting Enzyme Inhibitory Peptide from Yeast (Saccharomyces cerevisiae) January 2012
RAGE: a single receptor fits multiple ligands December 2011
Change in the Molecular Dimension of a RAGE-Ligand Complex Triggers RAGE Signaling September 2016
Structural Basis for Ligand Recognition and Activation of RAGE October 2010
The C-terminal acidic tail is responsible for the inhibitory effects of HMGB1 on efferocytosis August 2010
Production and application of HMGB1 derived recombinant RAGE-antagonist peptide for anti-inflammatory therapy in acute lung injury March 2018
Is RAGE still a therapeutic target for Alzheimer’s disease? May 2012
Binding studies of truncated variants of the Aβ peptide to the V-domain of the RAGE receptor reveal Aβ residues responsible for binding May 2011
Peptide Amphiphile Supramolecular Nanostructures as a Targeted Therapy for Atherosclerosis May 2019
Atheroma Niche-Responsive Nanocarriers for Immunotherapeutic Delivery January 2019
Peptide Amphiphile Nanostructures for Targeting of Atherosclerotic Plaque and Drug Delivery February 2018
Effects of acute Rho kinase inhibition on chronic hypoxia-induced changes in proximal and distal pulmonary arterial structure and function January 2011
Hypoxia Does neither Stimulate Pulmonary Artery Endothelial Cell Proliferation in Mice and Rats with Pulmonary Hypertension and Vascular Remodeling nor in Human Pulmonary Artery Endothelial Cells January 2011
Promotion of cell adherence and spreading: a novel function of RAGE, the highly selective differentiation marker of human alveolar epithelial type I cells November 2005
Cellular uptake of nanoparticles: journey inside the cell January 2017
RAGE and amyloid beta interactions: Atomic force microscopy and molecular modeling June 2005
Advanced Glycation End Product Recognition by the Receptor for AGEs May 2011
The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles November 2012
Cell death versus cell survival instructed by supramolecular cohesion of nanostructures February 2014
Biomolecular studies by circular dichroism January 2011
Programmable Assembly of Peptide Amphiphile via Noncovalent-to-Covalent Bond Conversion June 2017
Monodisperse cylindrical micelles by crystallization-driven living self-assembly May 2010
Development of Fractalkine-Targeted Nanofibers that Localize to Sites of Arterial Injury February 2020
Renal clearance of quantum dots September 2007
Local and Systemic RAGE Axis Changes in Pulmonary Hypertension: CTEPH and iPAH September 2014
Critical Role for the Advanced Glycation End‐Products Receptor in Pulmonary Arterial Hypertension Etiology January 2013
Pulmonary Arterial Hypertension September 2006
Hypoxia-Induced Pulmonary Vascular Remodeling: Cellular and Molecular Mechanisms September 2006
RAGE, vascular tone and vascular disease November 2009
RAGE mediates Aβ accumulation in a mouse model of Alzheimer’s disease via modulation of β- and γ-secretase activity January 2018
RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response May 2002
Blockade of RAGE Suppresses Alloimmune Reactions In Vitro and Delays Allograft Rejection in Murine Heart Transplantation February 2007
S100P-Derived RAGE Antagonistic Peptide Reduces Tumor Growth and Metastasis June 2012
Antibody drug conjugates against the receptor for advanced glycation end products (RAGE), a novel therapeutic target in endometrial cancer October 2019
Regulation of Human Melanoma Growth and Metastasis by AGE–AGE Receptor Interactions February 2004
Expression of receptors for advanced glycation end-products (RAGE) is closely associated with the invasive and metastatic activity of gastric cancer January 2002
The RAGE signaling pathway is involved in intestinal inflammation and represents a promising therapeutic target for Inflammatory Bowel Diseases December 2018
Contribution of receptor for advanced glycation end products to vasculature-protecting effects of exercise training in aged rats October 2014
Effects of RAGE-Specific Inhibitor FPS-ZM1 on Amyloid-β Metabolism and AGEs-Induced Inflammation and Oxidative Stress in Rat Hippocampus January 2016
Targeting of RAGE-ligand signaling impairs breast cancer cell invasion and metastasis September 2016
Blockade of RAGE ameliorates elastase‐induced emphysema development and progression via RAGE‐DAMP signaling February 2017
Clinical trial of an inhibitor of RAGE-A  interactions in Alzheimer disease April 2014
PF-04494700, an Oral Inhibitor of Receptor for Advanced Glycation End Products (RAGE), in Alzheimer Disease January 2011
Effect of TTP488 in patients with mild to moderate Alzheimer’s disease January 2014
Crucial role of RAGE in inappropriate increase of smooth muscle cells from patients with pulmonary arterial hypertension September 2018
Modified-Peptide Inhibitors of Amyloid β-Peptide Polymerization May 1999
Inhibition of Alzheimer's Amyloidosis by Peptides That Prevent β-Sheet Conformation September 1996
Controlling Amyloid β-Peptide Fibril Formation with Protease-stable Ligands May 1997
Arrest of -Amyloid Fibril Formation by a Pentapeptide Ligand April 1996
Site-Specific Blockade of RAGE-Vd Prevents Amyloid-  Oligomer Neurotoxicity May 2008
Biocatalytic self-assembly of 2D peptide-based nanostructures January 2011
Tyrosine-mediated two-dimensional peptide assembly and its role as a bio-inspired catalytic scaffold April 2014
Water-Floating Giant Nanosheets from Helical Peptide Pentamers September 2016
Bioactive molecular sheets from self-assembly of polymerizable peptides January 2008
Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity January 2012
Coassembled Cytotoxic and Pegylated Peptide Amphiphiles Form Filamentous Nanostructures with Potent Antitumor Activity in Models of Breast Cancer August 2012
Irena : tool suite for modeling and analysis of small-angle scattering February 2009
Echocardiography allows for analysis of pulmonary arterial flow in mice with congenital diaphragmatic hernia January 2018
A simple method for noninvasive estimation of pulmonary vascular resistance March 2003
Use of echocardiographic pulmonary acceleration time and estimated vascular resistance for the evaluation of possible pulmonary hypertension February 2013

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