Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo

Dubiella, Christian; Pinch, Benika J.; Koikawa, Kazuhiro; Zaidman, Daniel; Poon, Evon; Manz, Theresa D.; Nabet, Behnam; He, Shuning; Resnick, Efrat; Rogel, Adi; Langer, Ellen M.; Daniel, Colin J.; Seo, Hyuk-Soo; Chen, Ying; Adelmant, Guillaume; Sharifzadeh, Shabnam; Ficarro, Scott B.; Jamin, Yann; Costa, Barbara Martins da; Zimmerman, Mark W.; Lian, Xiaolan; m, Shin; Kozono, Shingo; Doctor, Zainab M.; Browne, Christopher M.; Yang, Annan; Stoler-Barak, Liat; Shah, Richa B.; Vangos, Nicholas E.; Geffken, Ezekiel A.; Oren, Roni; Koide, Eriko; Sidi, Samuel; Shulman, Ziv; Wang, Chu; Marto, Jarrod A.; Dhe-Paganon, Sirano; Look, Thomas; Zhou, Xiao Zhen; Lu, Kun Ping; Sears, Rosalie C.; Chesler, Louis; Gray, Nathanael S.; London, Nir

doi:10.1038/s41589-021-00786-7

Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo

Journal Article · 01 May 2021 · Nat. Chem. Biol.

DOI:https://doi.org/10.1038/s41589-021-00786-7· OSTI ID:1814970

Dubiella, Christian; Pinch, Benika J.; Koikawa, Kazuhiro; Zaidman, Daniel; Poon, Evon; Manz, Theresa D.; Nabet, Behnam; He, Shuning; Resnick, Efrat; Rogel, Adi; Langer, Ellen M.; Daniel, Colin J.; Seo, Hyuk-Soo; Chen, Ying; Adelmant, Guillaume; Sharifzadeh, Shabnam; Ficarro, Scott B.; Jamin, Yann; Costa, Barbara Martins da; Zimmerman, Mark W. more »

Research Organization:: Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)

Sponsoring Organization:: DOE - Office Of Science; National Institutes of Health (NIH)

OSTI ID:: 1814970

Journal Information:: Nat. Chem. Biol., Vol. 17

Country of Publication:: United States

Language:: ENGLISH

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