Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

Insights into the mismatch discrimination mechanism of Y-family DNA polymerase Dpo4

Journal Article · · Biochem. J.
DOI:https://doi.org/10.1042/BCJ20210162· OSTI ID:1798364

Research Organization:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
DOE - Office Of Science; National Institutes of Health (NIH)
OSTI ID:
1798364
Journal Information:
Biochem. J., Vol. 478, Issue (9)
Country of Publication:
United States
Language:
ENGLISH

References (41)

Mutagenesis by 8-oxoguanine: an enemy within journal July 1993
Review article: chronic inflammation and reactive oxygen and nitrogen metabolism - implications in DNA damage and mutagenesis: REVIEW: CHRONIC INFLAMMATION and MUTAGENESIS journal February 2000
Comparison of the mutagenic properties of 8-oxo-7,8-dihydro-2′-deoxyadenosine and 8-oxo-7,8-dihydro-2′-deoxyguanosine DNA lesions in mammalian cells journal December 1999
Fidelity of Nucleotide Insertion at 8-Oxo-7,8-dihydroguanine by Mammalian DNA Polymerase δ journal February 2001
Analysis of Nucleotide Insertion and Extension at 8-Oxo-7,8-dihydroguanine by Replicative T7 Polymerase exo - and Human Immunodeficiency Virus-1 Reverse Transcriptase Using Steady-State and Pre-Steady-State Kinetics journal May 1997
Efficient and accurate replication in the presence of 7,8-dihydro-8-oxoguanine by DNA polymerase η journal August 2000
Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion journal January 2006
Impact of Conformational Heterogeneity of OxoG Lesions and Their Pairing Partners on Bypass Fidelity by Y Family Polymerases journal May 2009
Repair of products of oxidative DNA base damage in human cells journal April 1996
Quantitative Measurement of Radiation-Induced Base Products in DNA Using Gas Chromatography-Mass Spectrometry journal August 1989
Opposite base-dependent excision of 7,8-dihydro-8-oxoadenine by the Ogg1 protein of Saccharomyces cerevisiae journal July 1998
7,8-dihydro-8-oxoadenine, a highly mutagenic adduct, is repaired by Escherichia coli and human mismatch-specific uracil/thymine-DNA glycosylases journal December 2012
The role of mammalian NEIL1 protein in the repair of 8-oxo-7,8-dihydroadenine in DNA journal March 2010
Mammalian 8-Oxoguanine DNA Glycosylase 1 Incises 8-Oxoadenine Opposite Cytosine in Nuclei and Mitochondria, while a Different Glycosylase Incises 8-Oxoadenine Opposite Guanine in Nuclei journal May 2003
RNA polymerase II bypasses 8-oxoguanine in the presence of transcription elongation factor TFIIS journal June 2007
Structure and in vitro replication of DNA templates containing 7,8-dihydro-8-oxoadenine journal January 1991
Insertion of dGMP and dAMP during in vitro DNA synthesis opposite an oxidized form of 7,8-dihydro-8-oxoguanine journal January 1999
8-Hydroxyadenine (7, 8-dihydro-8-Oxoadenine) induces misincorporation in in vitro DNA synthesis and mutations in NIH 3T3 cells journal January 1995
Conformation of guanine.cntdot.8-oxoadenine base pairs in the crystal structure of d(CGCGAATT(O8A)GCG) journal September 1992
Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases journal February 2019
Promutagenic bypass of 7,8-dihydro-8-oxoadenine by translesion synthesis DNA polymerase Dpo4 journal July 2020
Mutagenesis mechanism of the major oxidative adenine lesion 7,8-dihydro-8-oxoadenine journal April 2020
Crystal Structure of a Y-Family DNA Polymerase in Action journal October 2001
Structure of the Catalytic Core of S. cerevisiae DNA Polymerase η journal August 2001
Replication by human DNA polymerase-ι occurs by Hoogsteen base-pairing journal July 2004
Crystal Structure of the Catalytic Core of Human DNA Polymerase Kappa journal August 2004
Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4 journal May 2010
Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase journal February 2004
Replication of a cis–syn thymine dimer at atomic resolution journal August 2003
[20] Processing of X-ray diffraction data collected in oscillation mode book January 1997
Molecular replacement with MOLREP journal December 2009
Coot model-building tools for molecular graphics journal November 2004
PHENIX: a comprehensive Python-based system for macromolecular structure solution journal January 2010
MolProbity : all-atom structure validation for macromolecular crystallography journal December 2009
UCSF Chimera?A visualization system for exploratory research and analysis journal January 2004
Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2′-deoxyguanosine Bypass by Human DNA Polymerase η journal April 2014
Impact of Ribonucleotide Backbone on Translesion Synthesis and Repair of 7,8-Dihydro-8-oxoguanine journal November 2016
Multiple two-polymerase mechanisms in mammalian translesion DNA synthesis journal February 2010
Simultaneous Disruption of Two DNA Polymerases, Polη and Polζ, in Avian DT40 Cells Unmasks the Role of Polη in Cellular Response to Various DNA Lesions journal October 2010
Structure and mechanism of human DNA polymerase η journal June 2010
Nucleotide selection by the Y-family DNA polymerase Dpo4 involves template translocation and misalignment journal November 2013