skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Structure and function of yeast Atg20, a sorting nexin that facilitates autophagy induction

Journal Article · · Proceedings of the National Academy of Sciences of the United States of America

Research Organization:
Brookhaven National Laboratory (BNL), Upton, NY (United States)
Sponsoring Organization:
~OTHER
DOE Contract Number:
SC0012704
OSTI ID:
1786312
Report Number(s):
BNL-221617-2021-JACI
Journal Information:
Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 47
Country of Publication:
United States
Language:
English

References (59)

Extended String Binding Mode of the Phosphorylated Transactivation Domain of Tumor Suppressor p53 journal August 2014
Cargo Proteins Facilitate the Formation of Transport Vesicles in the Cytoplasm to Vacuole Targeting Pathway journal May 2004
Conditionally and Transiently Disordered Proteins: Awakening Cryptic Disorder To Regulate Protein Function journal December 2013
Amphipathic motifs in BAR domains are essential for membrane curvature sensing journal October 2009
Sorting nexins provide diversity for retromer-dependent trafficking events journal December 2011
A Phosphoserine−Lysine Salt Bridge within an α-Helical Peptide, the Strongest α-Helix Side-Chain Interaction Measured to Date journal May 2005
Sorting nexin 4 and amphiphysin 2, a new partnership between endocytosis and intracellular trafficking journal March 2003
ANCHOR: web server for predicting protein binding regions in disordered proteins journal August 2009
The role of the Atg1/ULK1 complex in autophagy regulation journal April 2010
A Multidimensional Chromatography Technology for In-depth Phosphoproteome Analysis journal April 2008
Determination of the regularization parameter in indirect-transform methods using perceptual criteria journal August 1992
The molecular machinery of autophagy: unanswered questions journal December 2004
Does Huntingtin play a role in selective macroautophagy? journal September 2010
The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling journal November 2005
Atg32 Is a Mitochondrial Protein that Confers Selectivity during Mitophagy journal July 2009
PRIMUS: a Windows PC-based system for small-angle scattering data analysis journal September 2003
Autophagic Processes in Yeast: Mechanism, Machinery and Regulation journal June 2013
An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol journal January 2008
Apg13p and Vac8p Are Part of a Complex of Phosphoproteins That Are Required for Cytoplasm to Vacuole Targeting journal June 2000
SNX–BAR proteins in phosphoinositide-mediated, tubular-based endosomal sorting journal June 2010
SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information text January 2014
A second set of loxP marker cassettes for Cre-mediated multiple gene knockouts in budding yeast journal March 2002
Classification of Intrinsically Disordered Regions and Proteins journal December 2013
Intrinsic Disorder-based Protein Interactions and their Modulators journal May 2013
PONDR-FIT: A meta-predictor of intrinsically disordered amino acids journal April 2010
The structural and functional signatures of proteins that undergo multiple events of post-translational modification: Structural and Functional Signatures of PTM Crosstalk journal June 2014
Net charge per residue modulates conformational ensembles of intrinsically disordered proteins journal April 2010
The BAR-domain family of proteins: a case of bending and binding?: The membrane bending and GTPase-binding functions of proteins from the BAR-domain family journal March 2004
Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae journal March 2002
Membrane curvature and mechanisms of dynamic cell membrane remodelling journal November 2005
Membrane-associated cargo recycling by tubule-based endosomal sorting journal July 2014
The identification and analysis of phosphorylation sites on the Atg1 protein kinase journal July 2011
The machinery of macroautophagy journal December 2013
Atg29 phosphorylation regulates coordination of the Atg17-Atg31-Atg29 complex with the Atg11 scaffold during autophagy initiation journal July 2013
Prediction of Protein Binding Regions in Disordered Proteins journal May 2009
MetaDisorder: a meta-server for the prediction of intrinsic disorder in proteins journal May 2012
DisProt: the Database of Disordered Proteins journal January 2007
Multisteric Regulation by Structural Disorder in Modular Signaling Proteins: An Extension of the Concept of Allostery journal December 2013
The importance of intrinsic disorder for protein phosphorylation journal February 2004
MoRFpred, a computational tool for sequence-based prediction and characterization of short disorder-to-order transitioning binding regions in proteins journal June 2012
The beginning of the end: how scaffolds nucleate autophagosome biogenesis journal January 2014
Membrane Fission Is Promoted by Insertion of Amphipathic Helices and Is Restricted by Crescent BAR Domains journal March 2012
Distinct complexes of yeast Snx4 family SNX-BARs mediate retrograde trafficking of Snc1 and Atg27 journal January 2017
The PX-BAR membrane-remodeling unit of sorting nexin 9 journal October 2007
Physicochemical Properties of Cells and Their Effects on Intrinsically Disordered Proteins (IDPs) text January 2014
Physicochemical Properties of Cells and Their Effects on Intrinsically Disordered Proteins (IDPs) journal December 2013
SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information journal April 2014
A Modular Polycistronic Expression System for Overexpressing Protein Complexes in Escherichia coli journal February 2001
Structure and flexibility within proteins as identified through small angle X-ray scattering journal January 2009
Cooperative Binding of the Cytoplasm to Vacuole Targeting Pathway Proteins, Cvt13 and Cvt20, to Phosphatidylinositol 3-Phosphate at the Pre-autophagosomal Structure Is Required for Selective Autophagy journal June 2002
Early Steps in Autophagy Depend on Direct Phosphorylation of Atg9 by the Atg1 Kinase journal February 2014
Mitophagy in yeast is independent of mitochondrial fission and requires the stress response gene WHI2 journal October 2011
Mitophagy in yeast is independent of mitochondrial fission and requires the stress response gene WHI2 journal March 2011
Endosomal sorting and signalling: an emerging role for sorting nexins journal June 2008
Molecular basis for SNX-BAR-mediated assembly of distinct endosomal sorting tubules: SNX-BAR-mediated formation of distinct sorting tubules journal October 2012
Effect of Phosphorylation on α-Helix Stability as a Function of Position journal February 2002
Assays for the biochemical and ultrastructural measurement of selective and nonselective types of autophagy in the yeast Saccharomyces cerevisiae journal March 2015
Atg11 Links Cargo to the Vesicle-forming Machinery in the Cytoplasm to Vacuole Targeting Pathway journal April 2005
Protein structure homology modeling using SWISS-MODEL workspace journal December 2008

Cited By (6)

Origin of the Autophagosome Membrane in Mammals journal September 2018
Retrograde trafficking and plasma membrane recycling pathways of the budding yeast Saccharomyces cerevisiae journal October 2019
The cryo-EM structure of the SNX–BAR Mvp1 tetramer journal March 2020
A heterodimeric SNX4:SNX7 SNX-BAR autophagy complex coordinates ATG9A trafficking for efficient autophagosome assembly journal January 2020
Sorting Nexins in Protein Homeostasis journal December 2020
Modeling membrane morphological change during autophagosome formation text January 2020

Similar Records

Structure and function of yeast Atg20, a sorting nexin that facilitates autophagy induction
Journal Article · 2017 · Proceedings of the National Academy of Sciences of the United States of America · OSTI ID:1786312

Mechanism of Aldolase Control of Sorting Nexin 9 Function in Endocytosis
Journal Article · 2010 · J. Biol. Chem. · OSTI ID:1786312

Structure and Plasticity of Endophilin and Sorting Nexin 9
Journal Article · 2009 · Structure · OSTI ID:1786312

Related Subjects