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Enterococcus faecium secreted antigen A generates muropeptides to enhance host immunity and limit bacterial pathogenesis

Journal Article · · eLife
DOI:https://doi.org/10.7554/eLife.45343· OSTI ID:1785451
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Research Organization:
Brookhaven National Lab. (BNL), Upton, NY (United States)
Sponsoring Organization:
~OTHER
DOE Contract Number:
SC0012704
OSTI ID:
1785451
Report Number(s):
BNL-221595-2021-JACI
Journal Information:
eLife, Vol. 8
Country of Publication:
United States
Language:
English

References (61)

The Phenix software for automated determination of macromolecular structures September 2011
Nod2: The intestinal gate keeper March 2017
Solution NMR Structure of the NlpC/P60 Domain of Lipoprotein Spr from Escherichia coli : Structural Evidence for a Novel Cysteine Peptidase Catalytic Triad † September 2008
The rise of the Enterococcus: beyond vancomycin resistance March 2012
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation November 2013
ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids May 2010
Structural basis of PcsB-mediated cell separation in Streptococcus pneumoniae May 2014
Peptidoglycan structure of Enterococcus faecium expressing vancomycin resistance of the VanB type February 1996
Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile October 2014
Microbiota-mediated colonization resistance against intestinal pathogens October 2013
Microbiota-activated PPAR-γ signaling inhibits dysbiotic Enterobacteriaceae expansion August 2017
NOD1 and NOD2: Signaling, Host Defense, and Inflammatory Disease December 2014
MolProbity : all-atom structure validation for macromolecular crystallography December 2009
IMG/M v.5.0: an integrated data management and comparative analysis system for microbial genomes and microbiomes October 2018
Muramyl Dipeptide Induces NOD2-Dependent Ly6Chigh Monocyte Recruitment to the Lungs and Protects Against Influenza Virus Infection May 2012
The Dual NOD1/NOD2 Agonism of Muropeptides Containing a Meso-Diaminopimelic Acid Residue August 2016
Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. pneumoniae colonization in mice September 2011
Impact of peptidoglycan O -acetylation on autolytic activities of the Enterococcus faecalis N -acetylglucosaminidase AtlA and N -acetylmuramidase AtlB August 2009
Coot model-building tools for molecular graphics November 2004
Glide:  A New Approach for Rapid, Accurate Docking and Scoring. 1. Method and Assessment of Docking Accuracy March 2004
Extra Precision Glide:  Docking and Scoring Incorporating a Model of Hydrophobic Enclosure for Protein−Ligand Complexes October 2006
Synthesis of crosslinked peptidoglycan fragments for investigation of their immunobiological functions July 2009
Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells November 2013
A simple model host for identifying Gram-positive virulence factors September 2001
Nod2 Is a General Sensor of Peptidoglycan through Muramyl Dipeptide (MDP) Detection March 2003
Peptidoglycan Molecular Requirements Allowing Detection by Nod1 and Nod2 July 2003
Lactate Racemization as a Rescue Pathway for Supplying d -Lactate to the Cell Wall Biosynthesis Machinery in Lactobacillus plantarum October 2005
Glide:  A New Approach for Rapid, Accurate Docking and Scoring. 2. Enrichment Factors in Database Screening March 2004
Modulating immunity as a therapy for bacterial infections March 2012
Dali: a network tool for protein structure comparison November 1995
The use of polyacrylamide-gel electrophoresis for the high-resolution separation of reducing saccharides labelled with the fluorophore 8-aminonaphthalene-1,3,6-trisulphonic acid. Detection of picomolar quantities by an imaging system based on a cooled charge-coupled device September 1990
NOD1 and NOD2: Beyond Peptidoglycan Sensing October 2017
Bacteriocin production augments niche competition by enterococci in the mammalian gastrointestinal tract October 2015
From cells to muropeptide structures in 24 h: Peptidoglycan mapping by UPLC-MS December 2014
Synthesis of Peptidoglycan Units with UDP at the Anomeric Position January 2005
Accurate Prediction of the Relative Potencies of Members of a Series of Kinase Inhibitors Using Molecular Docking and MM-GBSA Scoring August 2006
Phaser crystallographic software July 2007
Accessing Bioactive Natural Products from the Human Microbiome June 2018
Synthesis and biological evaluation of sugar-derived chiral nitroimidazoles as potential antimycobacterial agents September 2011
Oral application of romurtide, a synthetic muramyl dipeptide derivative, stimulates nonspecific resistance to microbial infections and hematopoiesis in mice August 1996
Muramyl Dipeptide and its Derivatives: Peptide Adjuvant in Immunological Disorders and Cancer Therapy September 2011
[20] Processing of X-ray diffraction data collected in oscillation mode January 1997
High-Quality Draft Genome Sequences of 28 Enterococcus sp. Isolates May 2010
Characterization of the Peptidoglycan of Vancomycin-Susceptible Enterococcus faecium July 2008
Exploiting a host-commensal interaction to promote intestinal barrier function and enteric pathogen tolerance September 2016
NOD proteins: regulators of inflammation in health and disease December 2013
A secreted bacterial peptidoglycan hydrolase enhances tolerance to enteric pathogens September 2016
The Toll-Like Receptor 2 Pathway Establishes Colonization by a Commensal of the Human Microbiota May 2011
Identification of a synthetic muramyl peptide derivative with enhanced Nod2 stimulatory capacity January 2013
Structure and Functional Regulation of RipA, a Mycobacterial Enzyme Essential for Daughter Cell Separation September 2010
The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis July 2013
An Enterococcus faecium Secreted Antigen, SagA, Exhibits Broad-Spectrum Binding to Extracellular Matrix Proteins and Appears Essential for E. faecium Growth September 2003
Friend Turned Foe: Evolution of Enterococcal Virulence and Antibiotic Resistance September 2014
Glycan Sequence-Dependent Nod2 Activation Investigated by Using a Chemically Synthesized Bacterial Peptidoglycan Fragment Library January 2013
An intermolecular binding mechanism involving multiple LysM domains mediates carbohydrate recognition by an endopeptidase February 2015
Structural Basis of Murein Peptide Specificity of a γ-D-Glutamyl-L-Diamino Acid Endopeptidase February 2009
Structure of the γ- D -glutamyl- L -diamino acid endopeptidase YkfC from Bacillus cereus in complex with L -Ala-γ- D -Glu: insights into substrate recognition by NlpC/P60 cysteine peptidases July 2010
Structures of a Bifunctional Cell Wall Hydrolase CwlT Containing a Novel Bacterial Lysozyme and an NlpC/P60 dl-Endopeptidase January 2014
Structure-Guided Functional Characterization of DUF1460 Reveals a Highly Specific NlpC/P60 Amidase Family December 2014
Insights into Substrate Specificity of NlpC/P60 Cell Wall Hydrolases Containing Bacterial SH3 Domains October 2015
Locating rearrangement events in a phylogeny based on highly fragmented assemblies January 2016

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