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Title: Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds

Patent ·
OSTI ID:1771632
;

Described herein are bacteriochlorins comprising an annulated isocyclic ring such as a compound Formula I: or a metal conjugate thereof, wherein: R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, and Z are each as defined herein. Also described are methods and intermediates for the synthesis of bacteriochlorins comprising an annulated isocyclic ring, and methods of using such bacteriochlorins for, among other things, diagnostic and therapeutic purposes such as, e.g., luminescent compounds in flow cytometry, and/or as active agents in photodynamic therapy (PDT).

Research Organization:
North Carolina State University, Raleigh, NC (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
FG02-05ER15661
Assignee:
North Carolina State University (Raleigh, NC)
Patent Number(s):
10,836,774
Application Number:
16/464,728
OSTI ID:
1771632
Resource Relation:
Patent File Date: 11/27/2017
Country of Publication:
United States
Language:
English

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