Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

Principles of RNA and nucleotide discrimination by the RNA processing enzyme RppH

Journal Article · · Nucleic Acids Research
DOI:https://doi.org/10.1093/nar/gkaa024· OSTI ID:1690118

Research Organization:
Brookhaven National Laboratory (BNL), Upton, NY (United States)
Sponsoring Organization:
~OTHER
DOE Contract Number:
SC0012704
OSTI ID:
1690118
Report Number(s):
BNL-220444-2020-JACI
Journal Information:
Nucleic Acids Research, Vol. 48, Issue 7
Country of Publication:
United States
Language:
English

References (49)

The evolution of function within the Nudix homology clan: Function Evolution in the Nudix Homology Clan journal March 2017
A Novel RNA Phosphorylation State Enables 5′ End-Dependent Degradation in Escherichia coli journal July 2017
Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli journal June 2009
HPLC-based quantification of bacterial housekeeping nucleotides and alarmone messengers ppGpp and pppGpp journal September 2017
RppH-dependent pyrophosphohydrolysis of mRNAs is regulated by direct interaction with DapF in Escherichia coli journal October 2014
Structural and kinetic insights into stimulation of RppH-dependent RNA degradation by the metabolic enzyme DapF journal May 2018
DapF stabilizes the substrate-favoring conformation of RppH to stimulate its RNA-pyrophosphohydrolase activity in Escherichia coli journal June 2018
Specificity and Evolutionary Conservation of the Escherichia coli RNA Pyrophosphohydrolase RppH journal February 2015
Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates journal April 2013
Structure and Biological Function of the RNA Pyrophosphohydrolase BdRppH from Bdellovibrio bacteriovorus journal March 2009
Specificity of RppH-dependent RNA degradation in Bacillus subtilis journal April 2013
Dimerization of Bacterial Diaminopimelate Epimerase Is Essential for Catalysis journal February 2013
XDS journal January 2010
PHENIX: a comprehensive Python-based system for macromolecular structure solution journal January 2010
Features and development of Coot journal March 2010
A method for the concentration and for the colorimetric determination of nanomoles of inorganic pyrophosphate journal October 1981
Colorimetric determination of inorganic pyrophosphate by a manual or automated method journal September 1975
Differential Control of the Rate of 5'-End-Dependent mRNA Degradation in Escherichia coli journal September 2012
pH homeostasis in Escherichia coli: measurement by 31P nuclear magnetic resonance of methylphosphonate and phosphate. journal October 1981
pH of the Cytoplasm and Periplasm of Escherichia coli: Rapid Measurement by Green Fluorescent Protein Fluorimetry journal June 2007
The relationship between intracellular pH, the pH gradient and potassium transport in Escherichia coli journal December 1983
Initiation of RNA Decay in Escherichia coli by 5′ Pyrophosphate Removal journal July 2007
The NudA Protein in the Gastric Pathogen Helicobacter pylori Is an Ubiquitous and Constitutively Expressed Dinucleoside Polyphosphate Hydrolase journal January 2003
The Gene, ialA , Associated with the Invasion of Human Erythrocytes by Bartonella bacilliformis , Designates a Nudix Hydrolase Active on Dinucleoside 5′-Polyphosphates journal January 1999
The Gene ygdP, Associated with the Invasiveness ofEscherichia coli K1, Designates a Nudix Hydrolase, Orf176, Active on Adenosine (5′)-Pentaphospho-(5′)-adenosine (Ap5A) journal October 2001
Structures and mechanisms of Nudix hydrolases journal January 2005
The Nudix hydrolase superfamily journal December 2005
Basal ppGpp level adjustment shown by new spoT mutants affect steady state growth rates and rrnA ribosomal promoter regulation in Escherichia coli journal August 1988
Novel (p)ppGpp Binding and Metabolizing Proteins of Escherichia coli journal March 2018
TheIalAInvasion Gene ofBartonella bacilliformisEncodes a (Di)Nucleoside Polyphosphate Hydrolase of the MutT Motif Family and Has Homologs in Other Invasive Bacteria journal March 1999
Reversible Inhibition of Escherichia coli Inorganic Pyrophosphatase by Fluoride: Trapped Catalytic Intermediates in Cryo-crystallographic Studies journal March 2007
MgF3− as a Transition State Analog of Phosphoryl Transfer journal March 2002
CheckMyMetal : a macromolecular metal-binding validation tool journal February 2017
Crystal structure of human diphosphoinositol phosphatase 1 journal October 2009
Hydrolysis of diadenosine polyphosphates. Exploration of an additional role of Mycobacterium smegmatis MutT1 journal September 2017
K+/H+ antiporter functions as a regulator of cytoplasmic pH in a marine bacterium, Vibrio alginolyticus journal October 1984
'In-line attack' conformational effect plays a modest role in an enzyme-catalyzed RNA cleavage: a free energy simulation study journal June 2007
Hydrolysis of diazomethane-kinetics and mechanism journal September 1980
Identification of Escherichia coli K1 genes contributing to human brain microvascular endothelial cell invasion by differential fluorescence induction journal April 2000
Transcriptional Analysis of Rickettsia prowazekii Invasion Gene Homolog (invA) during Host Cell Infection journal November 2002
Transcriptional Analysis of Rickettsia prowazekii Invasion Gene Homolog ( invA ) during Host Cell Infection journal February 2003
PHENIX: a comprehensive Python-based system for macromolecular structure solution. text January 2010
Solubilization and reconstitution of the Na+‐motive NADH oxidase activity from the marine bacterium Vibrio alginolyticus journal October 1984
Fluoride is a strong and specific inhibitor of ( asymmetrical ) Ap 4 A hydrolases journal March 1990
Structures of RNA Complexes with the Escherichia coli RNA Pyrophosphohydrolase RppH Unveil the Basis for Specific 5′-End-dependent mRNA Decay journal February 2015
Relationship between Growth Rate and ATP Concentration in Escherichia coli : A BIOASSAY FOR AVAILABLE CELLULAR ATP journal December 2003
The Rickettsia prowazekii Invasion Gene Homolog ( invA ) Encodes a Nudix Hydrolase Active on Adenosine (5′)-pentaphospho-(5′)-adenosine journal January 2002
Characterization of a two-gene locus from Bartonella bacilliformis associated with the ability to invade human erythrocytes. journal January 1995
Legionella pneumophila NudA Is a Nudix Hydrolase and Virulence Factor journal September 2005