Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

Structural basis of Q-dependent antitermination

Journal Article · · Proceedings of the National Academy of Sciences of the United States of America

Research Organization:
Brookhaven National Laboratory (BNL), Upton, NY (United States)
Sponsoring Organization:
~OTHER
DOE Contract Number:
SC0012704
OSTI ID:
1689959
Report Number(s):
BNL-220288-2020-JACI
Journal Information:
Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, Issue 37
Country of Publication:
United States
Language:
English

References (58)

Transcription termination and late control in phage lambda. journal September 1975
The phage λ Q gene product: Activity of a transcription antiterminator in vitro journal September 1982
Function of a nontranscribed DNA strand site in transcription elongation journal July 1994
Mechanism of Intrinsic Transcription Termination and Antitermination journal April 1999
RNA-Mediated Destabilization of the σ70 Region 4/β Flap Interaction Facilitates Engagement of RNA Polymerase by the Q Antiterminator journal November 2006
The bacteriophage ?Q anti-terminator protein regulates late gene expression as a stable component of the transcription elongation complex journal February 2007
The bacteriophage λ Q antiterminator protein contacts the β-flap domain of RNA polymerase journal October 2008
Antitermination by Bacteriophage   Q Protein journal January 1998
Processive Antitermination journal January 1999
Termination and antitermination: RNA polymerase runs a stop sign journal April 2011
Characterization of the late-gene regulatory region of phage 21. journal February 1991
Bacterial Sigma Factors: A Historical, Structural, and Genomic Perspective journal September 2014
Extra Cytoplasmic Function sigma factors, recent structural insights into promoter recognition and regulation journal February 2015
σ70-dependent Transcription Pausing in Escherichia coli journal October 2011
Structural transitions in the transcription elongation complexes of bacterial RNA polymerase during σ-dependent pausing journal December 2011
Regulation of promoter-proximal transcription elongation: enhanced DNA scrunching drives λQ antiterminator-dependent escape from a σ70-dependent pause journal February 2014
Two transcription pause elements underlie a σ 70 -dependent pause cycle journal July 2015
A universal transcription pause sequence is an element of initiation factor σ70-dependent pausing journal April 2016
Function of Transcription Cleavage Factors GreA and GreB at a Regulatory Pause Site journal December 2000
RNA Polymerase Accommodates a Pause RNA Hairpin by Global Conformational Rearrangements that Prolong Pausing journal March 2018
Structural Basis for NusA Stabilized Transcriptional Pausing journal March 2018
Mechanisms of Transcriptional Pausing in Bacteria journal September 2019
Mechanisms of Bacterial Transcription Termination journal September 2019
Structural Basis for Transcript Elongation Control by NusG Family Universal Regulators journal June 2018
The Mechanisms of Substrate Selection, Catalysis, and Translocation by the Elongating RNA Polymerase journal September 2019
Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor journal April 2019
Specificity and mechanism of antitermination by Q proteins of bacteriophages λ and 82 journal December 1989
Structure of the DNA-Binding and RNA-Polymerase-Binding Region of Transcription Antitermination Factor λQ journal March 2014
Nascent RNA length dictates opposing effects of NusA on antitermination journal March 2016
Structural basis of Q-dependent transcription antitermination journal July 2019
Single-particle cryo-EM—How did it get here and where will it go journal August 2018
UCSF Chimera?A visualization system for exploratory research and analysis journal January 2004
Resolution of phase ambiguity in macromolecular crystallography book January 1985
Transcript cleavage factors from E. coli journal February 1993
Inference of Macromolecular Assemblies from Crystalline State journal September 2007
Automated electron microscope tomography using robust prediction of specimen movements journal October 2005
Gctf: Real-time CTF determination and correction journal January 2016
Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble journal May 2015
A combined approach to improving large-scale production of tobacco etch virus protease journal September 2007
High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy journal December 2013
Crystal Structure of Escherichia coli σE with the Cytoplasmic Domain of Its Anti-σ RseA journal April 2003
Structural basis for substrate loading in bacterial RNA polymerase journal June 2007
Prevention of overfitting in cryo-EM structure determination journal July 2012
MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy journal February 2017
The interaction between  70 and the  -flap of Escherichia coli RNA polymerase inhibits extension of nascent RNA during early elongation journal March 2005
Structures of E . coli σ S -transcription initiation complexes provide new insights into polymerase mechanism journal March 2016
The nudeotide sequence of the cloned rpoD gene for the RNA polymerase sigma subunit from E. coil K12 journal January 1981
Dali server: conservation mapping in 3D journal May 2010
The Structural Basis for Promoter −35 Element Recognition by the Group IV σ Factors journal August 2006
PHENIX: a comprehensive Python-based system for macromolecular structure solution. text January 2010
Outcome of the first electron microscopy validation task force meeting text January 2012
Transcription inhibition by the depsipeptide antibiotic salinamide A journal April 2014
Outcome of the First Electron Microscopy Validation Task Force Meeting journal February 2012
Purification of Bacterial RNA Polymerase: Tools and Protocols book January 2015
The phage λ gene Q transcription antiterminator binds DNA in the late gene promoter as it modifies RNA polymerase journal June 1992
Correlating solvation free energies and surface tensions of hydrocarbon solutes journal August 1994
Function of E. coli RNA Polymerase σ Factor- σ70 in Promoter-Proximal Pausing journal August 1996
Phage lambda gene Q antiterminator recognizes RNA polymerase near the promoter and accelerates it through a pause site journal August 1985

Cited By (3)

Exploiting phage strategies to modulate bacterial transcription journal October 2019
Structural basis for transcription inhibition by E. coli SspA journal August 2020
Structural basis of transcription-translation coupling journal August 2020

Similar Records

Structural basis of Q-dependent antitermination
Journal Article · 2019 · Proceedings of the National Academy of Sciences of the United States of America · OSTI ID:1570741

Structure of the DNA-binding and RNA Polymerase-binding Region of Transcription Antitermination Factor Q
Journal Article · 2014 · Structure · OSTI ID:1162942

Structural basis for RNA recognition by NusB and NusE in the initiation of transcription antitermination
Journal Article · 2012 · Nucleic Acids Research · OSTI ID:1036329

Related Subjects