Linking Crystallographic Model and Data Quality
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May 2012 |
Middle East Respiratory Syndrome Coronavirus Causes Multiple Organ Damage and Lethal Disease in Mice Transgenic for Human Dipeptidyl Peptidase 4
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October 2015 |
Inhibition of norovirus 3CL protease by bisulfite adducts of transition state inhibitors
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January 2013 |
Developments in the CCP 4 molecular-graphics project
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November 2004 |
Structures of the Middle East respiratory syndrome coronavirus 3C-like protease reveal insights into substrate specificity
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April 2015 |
Principles and approaches for reproducible scoring of tissue stains in research
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May 2018 |
Structure-Guided Design and Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease. Structure–Activity Relationships and Biochemical, X-ray Crystallographic, Cell-Based, and In Vivo Studies
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March 2015 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection
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February 2020 |
Broad-Spectrum Antivirals against 3C or 3C-Like Proteases of Picornaviruses, Noroviruses, and Coronaviruses
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August 2012 |
Towards automated crystallographic structure refinement with phenix.refine
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March 2012 |
Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element
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April 2018 |
A Novel, Nonaqueous Method for Regeneration of Aldehydes from Bisulfite Adducts
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July 1999 |
Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys
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March 2016 |
ACE2 Receptor Expression and Severe Acute Respiratory Syndrome Coronavirus Infection Depend on Differentiation of Human Airway Epithelia
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December 2005 |
Clinicopathologic, Immunohistochemical, and Ultrastructural Findings of a Fatal Case of Middle East Respiratory Syndrome Coronavirus Infection in the United Arab Emirates, April 2014
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March 2016 |
Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome: Current Therapeutic Options and Potential Targets for Novel Therapies
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November 2017 |
Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses
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June 2017 |
Efficacy of a 3C-like protease inhibitor in treating various forms of acquired feline infectious peritonitis
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May 2017 |
Generation of a Transgenic Mouse Model of Middle East Respiratory Syndrome Coronavirus Infection and Disease
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January 2015 |
Rapid generation of a mouse model for Middle East respiratory syndrome
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March 2014 |
Coronaviruses — drug discovery and therapeutic options
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February 2016 |
Scaling and assessment of data quality
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December 2005 |
Respiratory disease in rhesus macaques inoculated with SARS-CoV-2
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May 2020 |
XDS
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January 2010 |
From SARS to MERS: crystallographic studies on coronaviral proteases enable antiviral drug design
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August 2014 |
Recent Aspects on the Pathogenesis Mechanism, Animal Models and Novel Therapeutic Interventions for Middle East Respiratory Syndrome Coronavirus Infections
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journal
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March 2019 |
Protease inhibitors broadly effective against feline, ferret and mink coronaviruses
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journal
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December 2018 |
Mouse-adapted MERS coronavirus causes lethal lung disease in human DPP4 knockin mice
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journal
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March 2017 |
Broad-Spectrum Inhibitors against 3C-Like Proteases of Feline Coronaviruses and Feline Caliciviruses
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journal
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February 2015 |
Broad-spectrum coronavirus antiviral drug discovery
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journal
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February 2019 |
Prediction and biochemical analysis of putative cleavage sites of the 3C-like protease of Middle East respiratory syndrome coronavirus
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October 2015 |
Potent inhibition of norovirus 3CL protease by peptidyl α-ketoamides and α-ketoheterocycles
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journal
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July 2012 |
Improved R-factors for diffraction data analysis in macromolecular crystallography
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journal
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April 1997 |
An efficient synthesis of a key intermediate for the preparation of the rhinovirus protease inhibitor AG7088 via asymmetric dianionic cyanomethylation of N-Boc-l-(+)-glutamic acid dimethyl ester
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September 2001 |
Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors
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March 2020 |
MolProbity : all-atom structure validation for macromolecular crystallography
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December 2009 |
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice
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April 2020 |
Features and development of Coot
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March 2010 |
Resolving Some Old Problems in Protein Crystallography
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May 2012 |
An introduction to data reduction: space-group determination, scaling and intensity statistics
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journal
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March 2011 |
Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 4. Incorporation of P 1 Lactam Moieties as l -Glutamine Replacements
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journal
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April 1999 |
Potent inhibition of feline coronaviruses with peptidyl compounds targeting coronavirus 3C-like protease
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journal
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February 2013 |
Structure-based exploration and exploitation of the S4 subsite of norovirus 3CL protease in the design of potent and permeable inhibitors
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journal
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January 2017 |
Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV
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journal
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January 2020 |
Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor
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journal
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March 2016 |
Data processing and analysis with the autoPROC toolbox
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journal
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March 2011 |
A Novel Coronavirus from Patients with Pneumonia in China, 2019
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journal
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February 2020 |
Automatic indexing of rotation diffraction patterns
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February 1988 |
Design, synthesis, and bioevaluation of viral 3C and 3C-like protease inhibitors
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December 2013 |
Phaser crystallographic software
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July 2007 |
Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding
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February 2020 |