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Title: A Fully Integrated and Self-Powered Smartwatch for Continuous Sweat Glucose Monitoring

Abstract

Wearable devices for health monitoring and fitness management have foreseen a rapidly expanding market, especially those for noninvasive and continuous measurements with real-time display that provide practical convenience and eliminated safety/infection risks. In this research, a self-powered and fully integrated smartwatch that consists of flexible photovoltaic cells and rechargeable batteries in the forms of a “watch strap”, electrochemical glucose sensors, customized circuits, and display units integrated into a “dial” platform is successfully fabricated for real-time and continuous monitoring of sweat glucose levels. The functionality of the smartwatch, including sweat glucose sensing, signal processing, and display, can be supported with the harvested/converted solar energy without external charging devices. The Zn-MnO 2 batteries serve as intermediate energy storage units and the utilization of aqueous electrolytes eliminated safety concerns for batteries, which is critical for wearable devices. Such a wearable system in a smartwatch fashion realizes integration of energy modules with self-powered capability, electrochemical sensors for noninvasive glucose monitoring, and in situ and real-time signal processing/display in a single platform for the first time. The as-fabricated fully integrated and self-powered smartwatch also provides a promising protocol for statistical study and clinical investigation to reveal correlations between sweat compositions and human body dynamics.

Authors:
 [1]; ORCiD logo [2];  [3]; ORCiD logo [4]; ORCiD logo [4];  [4];  [3]; ORCiD logo [4];  [4]; ORCiD logo [5]; ORCiD logo [4]
  1. Univ. of California, Berkeley, CA (United States). Dept. of Electrical Engineering and Computer Sciences and Berkeley Sensor and Actuator Center; Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Materials Sciences Division; Sichuan Univ., Chengdu (China). Polymer Research Inst., State Key Lab. of Polymer Materials
  2. Univ. of California, Berkeley, CA (United States). Dept. of Electrical Engineering and Computer Sciences and Berkeley Sensor and Actuator Center; Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Materials Sciences Division; Hong Kong Univ. of Science and Technology, Hong Kong (China). Dept. of Electronic and Computer Engineering
  3. Univ. of California, Berkeley, CA (United States). Dept. of Electrical Engineering and Computer Sciences
  4. Univ. of California, Berkeley, CA (United States). Dept. of Electrical Engineering and Computer Sciences and Berkeley Sensor and Actuator Center; Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Materials Sciences Division
  5. Hong Kong Univ. of Science and Technology, Hong Kong (China). Dept. of Electronic and Computer Engineering
Publication Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE Office of Science (SC), Basic Energy Sciences (BES). Materials Sciences & Engineering Division; National Science Foundation (NSF)
OSTI Identifier:
1638991
Grant/Contract Number:  
AC02-05CH11231
Resource Type:
Journal Article: Accepted Manuscript
Journal Name:
ACS Sensors
Additional Journal Information:
Journal Volume: 4; Journal Issue: 7; Journal ID: ISSN 2379-3694
Publisher:
American Chemical Society (ACS)
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION; flexible biosensors; noninvasive glucose monitoring; self-powered system; wearable electronics; healthcare and fitness management

Citation Formats

Zhao, Jiangqi, Lin, Yuanjing, Wu, Jingbo, Nyein, Hnin Yin Yin, Bariya, Mallika, Tai, Li-Chia, Chao, Minghan, Ji, Wenbo, Zhang, George, Fan, Zhiyong, and Javey, Ali. A Fully Integrated and Self-Powered Smartwatch for Continuous Sweat Glucose Monitoring. United States: N. p., 2019. Web. doi:10.1021/acssensors.9b00891.
Zhao, Jiangqi, Lin, Yuanjing, Wu, Jingbo, Nyein, Hnin Yin Yin, Bariya, Mallika, Tai, Li-Chia, Chao, Minghan, Ji, Wenbo, Zhang, George, Fan, Zhiyong, & Javey, Ali. A Fully Integrated and Self-Powered Smartwatch for Continuous Sweat Glucose Monitoring. United States. https://doi.org/10.1021/acssensors.9b00891
Zhao, Jiangqi, Lin, Yuanjing, Wu, Jingbo, Nyein, Hnin Yin Yin, Bariya, Mallika, Tai, Li-Chia, Chao, Minghan, Ji, Wenbo, Zhang, George, Fan, Zhiyong, and Javey, Ali. Thu . "A Fully Integrated and Self-Powered Smartwatch for Continuous Sweat Glucose Monitoring". United States. https://doi.org/10.1021/acssensors.9b00891. https://www.osti.gov/servlets/purl/1638991.
@article{osti_1638991,
title = {A Fully Integrated and Self-Powered Smartwatch for Continuous Sweat Glucose Monitoring},
author = {Zhao, Jiangqi and Lin, Yuanjing and Wu, Jingbo and Nyein, Hnin Yin Yin and Bariya, Mallika and Tai, Li-Chia and Chao, Minghan and Ji, Wenbo and Zhang, George and Fan, Zhiyong and Javey, Ali},
abstractNote = {Wearable devices for health monitoring and fitness management have foreseen a rapidly expanding market, especially those for noninvasive and continuous measurements with real-time display that provide practical convenience and eliminated safety/infection risks. In this research, a self-powered and fully integrated smartwatch that consists of flexible photovoltaic cells and rechargeable batteries in the forms of a “watch strap”, electrochemical glucose sensors, customized circuits, and display units integrated into a “dial” platform is successfully fabricated for real-time and continuous monitoring of sweat glucose levels. The functionality of the smartwatch, including sweat glucose sensing, signal processing, and display, can be supported with the harvested/converted solar energy without external charging devices. The Zn-MnO2 batteries serve as intermediate energy storage units and the utilization of aqueous electrolytes eliminated safety concerns for batteries, which is critical for wearable devices. Such a wearable system in a smartwatch fashion realizes integration of energy modules with self-powered capability, electrochemical sensors for noninvasive glucose monitoring, and in situ and real-time signal processing/display in a single platform for the first time. The as-fabricated fully integrated and self-powered smartwatch also provides a promising protocol for statistical study and clinical investigation to reveal correlations between sweat compositions and human body dynamics.},
doi = {10.1021/acssensors.9b00891},
url = {https://www.osti.gov/biblio/1638991}, journal = {ACS Sensors},
issn = {2379-3694},
number = 7,
volume = 4,
place = {United States},
year = {2019},
month = {7}
}

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Works referencing / citing this record:

Wearable biochemical sensors for human health monitoring: sensing materials and manufacturing technologies
journal, January 2020


Review—Energy Autonomous Wearable Sensors for Smart Healthcare: A Review
journal, January 2020


The recent advances in self‐powered medical information sensors
journal, December 2019