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A cysteinyl-tRNA synthetase variant confers resistance against selenite toxicity and decreases selenocysteine misincorporation

Journal Article · · Journal of Biological Chemistry

Not provided.

Research Organization:
Yale Univ., New Haven, CT (United States)
Sponsoring Organization:
USDOE Office of Science (SC)
DOE Contract Number:
FG02-98ER20311
OSTI ID:
1610396
Journal Information:
Journal of Biological Chemistry, Vol. 294, Issue 34; ISSN 0021-9258
Publisher:
American Society for Biochemistry and Molecular Biology
Country of Publication:
United States
Language:
English

References (56)

Why Nature Chose Selenium journal February 2016
Selenium and Selenocysteine in Protein Chemistry journal November 2017
Catalysis of Electron Transfer by Selenocysteine journal May 2006
Selenols catalyze the interchange reactions of dithiols and disulfides in water journal November 1991
Comparison of the chemical properties of selenocysteine and selenocystine with their sulfur analogs journal October 1967
RNA-dependent conversion of phosphoserine forms selenocysteine in eukaryotes and archaea journal December 2006
Biosynthesis of Selenocysteine on Its tRNA in Eukaryotes journal December 2006
The many levels of control on bacterial selenoprotein synthesis journal November 2009
The path of unspecific incorporation of selenium in Escherichia coli journal October 1997
Aminoacylation of Escherichia coli cysteine tRNA by selenocysteine journal December 1975
Cysteinyl-tRNA Synthetase from Phaseolus aureus: Purification and Properties journal November 1977
Utilization of Selenocysteine by a Cysteinyl-tRNA Synthetase from Phaseolus aureus journal September 1976
Reduction of dl-selenocystine and isolation of l-seleoncysteine journal April 1980
Cysteinyl-tRNA Synthetase from Astragalus Species journal June 1979
Selenium in global food systems journal May 2001
An Overview of Selenium Uptake, Metabolism, and Toxicity in Plants journal January 2017
Selenium in agriculture and the environment journal April 1984
Exclusion of Selenium from Proteins of Selenium-Tolerant Astragalus Species journal May 1981
A Facile Method for Producing Selenocysteine-Containing Proteins journal May 2018
De Novo Transcriptome Assembly and Comparative Analysis Elucidate Complicated Mechanism Regulating Astragalus chrysochlorus Response to Selenium Stimuli journal October 2015
Structural origins of amino acid selection without editing by cysteinyl-tRNA synthetase journal June 2002
Zinc-mediated Amino Acid Discrimination in Cysteinyl-tRNA Synthetase journal April 2003
Draft genome of the wheat A-genome progenitor Triticum urartu journal March 2013
Tolerance of wheat (Triticum aestivum L.) to high soil and solution selenium levels journal March 2005
Temperature-sensitive mutants in cysteinyl-tRNA ligase of E. coli K-12 journal October 1979
Trans-sulfuration Pathway Seleno-amino Acids Are Mediators of Selenomethionine Toxicity in Saccharomyces cerevisiae * journal March 2015
Exposure to selenomethionine causes selenocysteine misincorporation and protein aggregation in Saccharomyces cerevisiae journal March 2017
Genome-wide screen of Saccharomyces cerevisiae null allele strains identifies genes involved in selenomethionine resistance journal November 2008
Blocking S-adenosylmethionine synthesis in yeast allows selenomethionine incorporation and multiwavelength anomalous dispersion phasing journal April 2007
A Quantitative Chemoproteomic Platform to Monitor Selenocysteine Reactivity within a Complex Proteome journal September 2018
Isotopically-Labeled Iodoacetamide-Alkyne Probes for Quantitative Cysteine-Reactivity Profiling journal November 2017
Spatial Imaging, Speciation, and Quantification of Selenium in the Hyperaccumulator Plants Astragalus bisulcatus and Stanleya pinnata journal August 2006
Rate-Limiting Steps in Selenium Assimilation and Volatilization by Indian Mustard journal August 1998
Volatilization of selenium from plants and soils journal January 1984
Accumulation and volatilization of different chemical species of selenium by plants journal August 1998
Analysis of sulfur and selenium assimilation in Astragalus plants with varying capacities to accumulate selenium: Sulfur and selenium assimilation in Astragalus journal May 2005
Overexpression of Selenocysteine Methyltransferase in Arabidopsis and Indian Mustard Increases Selenium Tolerance and Accumulation journal December 2003
Phytoremediation of selenium using transgenic plants journal April 2009
Functional profiling of the Saccharomyces cerevisiae genome journal July 2002
Fast, scalable generation of high‐quality protein multiple sequence alignments using Clustal Omega journal January 2011
Jalview Version 2--a multiple sequence alignment editor and analysis workbench journal January 2009
Recoding of the selenocysteine UGA codon by cysteine in the presence of a non-canonical tRNA Cys and elongation factor SelB journal November 2017
Methods for kinetic and thermodynamic analysis of aminoacyl-tRNA synthetases journal February 2008
Substrate-mediated Fidelity Mechanism Ensures Accurate Decoding of Proline Codons journal July 2011
Selenocysteine in Native Chemical Ligation and Expressed Protein Ligation journal May 2001
[3′-32P]-labeling tRNA with nucleotidyltransferase for assaying aminoacylation and peptide bond formation journal February 2008
An Isotopically Tagged Azobenzene-Based Cleavable Linker for Quantitative Proteomics journal July 2013
Tandem orthogonal proteolysis-activity-based protein profiling (TOP-ABPP)—a general method for mapping sites of probe modification in proteomes journal May 2007
An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database journal November 1994
DTASelect and Contrast:  Tools for Assembling and Comparing Protein Identifications from Shotgun Proteomics journal February 2002
Quantitative reactivity profiling predicts functional cysteines in proteomes journal November 2010
Uptake of Selenite by Saccharomyces cerevisiae Involves the High and Low Affinity Orthophosphate Transporters journal August 2010
Jen1p: A High Affinity Selenite Transporter in Yeast journal November 2010
Recent advances in the mechanism of selenoamino acids toxicity in eukaryotic cells journal January 2017
Methylselenol Formed by Spontaneous Methylation of Selenide Is a Superior Selenium Substrate to the Thioredoxin and Glutaredoxin Systems journal November 2012
Isolation and Characterization of cysK Mutants of Escherichia coli K12 journal November 1977