Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

Check valves for microfluidic systems and methods thereof

Patent ·
OSTI ID:1600287

The present invention relates to microfluidic check valves, as well as fluidic cartridges including such check valves. In particular examples, the check valve includes a pre-stressed spring formed from a planar substrate. Various characteristics of the valves, such as size, profile, opening pressure, etc., can be tuned to provide desired performance when employed within a fluidic cartridge.

Research Organization:
Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC04-94AL85000
Assignee:
National Technology & Engineering Solutions of Sandia, LLC (Albuquerque, NM)
Patent Number(s):
10,478,818
Application Number:
15/447,581
OSTI ID:
1600287
Country of Publication:
United States
Language:
English

References (17)

Disposable miniature check valve design suitable for scalable manufacturing journal December 2013
A simple check valve for microfluidic point of care diagnostics journal January 2016
Modelling, characterization and testing of an ortho-planar micro-valve journal November 2008
Direct Blood Dry LAMP: A Rapid, Stable, and Easy Diagnostic Tool for Human African Trypanosomiasis journal March 2015
Wireless implantable chip with integrated nitinol-based pump for radio-controlled local drug delivery journal January 2015
Characteristic studies of the piezoelectrically actuated micropump with check valve journal June 2013
Real-Time Reverse Transcription Loop-Mediated Isothermal Amplification for Rapid Detection of West Nile Virus journal January 2004
Development of novel passive check valves for the microfluidic CD platform journal February 2015
Squeeze-chip: a finger-controlled microfluidic flow network device and its application to biochemical assays journal January 2012
Rapid prototyping of robust and versatile microfluidic components using adhesive transfer tapes journal January 2010
The Development of Lyophilized Loop-mediated Isothermal Amplification Reagents for the Detection of Coxiella burnetii journal April 2016
Surveillance for Western Equine Encephalitis, St. Louis Encephalitis, and West Nile Viruses Using Reverse Transcription Loop-Mediated Isothermal Amplification journal January 2016
Quenching of Unincorporated Amplification Signal Reporters in Reverse-Transcription Loop-Mediated Isothermal Amplification Enabling Bright, Single-Step, Closed-Tube, and Multiplexed Detection of RNA Viruses journal March 2016
Simultaneous metering and dispensing of multiple reagents on a passively controlled microdevice solely by finger pressing journal January 2015
Micro check valves for integration into polymeric microfluidic devices journal August 2003
Polymerase chain reaction compatibility of adhesive transfer tape based microfluidic platforms journal August 2013
Polymer microvalve with pre-stressed membranes for tunable flow–pressure characteristics journal August 2010