skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Structural basis for influenza virus NS1 protein block of mRNA nuclear export

Authors:
; ; ; ; ; ; ; ;
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Org.:
USDOE Office of Science (SC)
OSTI Identifier:
1593437
Resource Type:
Journal Article
Journal Name:
Nat. Microbio.
Additional Journal Information:
Journal Volume: 4; Journal Issue: 2019
Country of Publication:
United States
Language:
ENGLISH

Citation Formats

Zhang, Ke, Xie, Yihu, Muñoz-Moreno, Raquel, Wang, Juan, Zhang, Liang, Esparza, Matthew, García-Sastre, Adolfo, Fontoura, Beatriz M.A., and Ren, Yi. Structural basis for influenza virus NS1 protein block of mRNA nuclear export. United States: N. p., 2020. Web. doi:10.1038/s41564-019-0482-x.
Zhang, Ke, Xie, Yihu, Muñoz-Moreno, Raquel, Wang, Juan, Zhang, Liang, Esparza, Matthew, García-Sastre, Adolfo, Fontoura, Beatriz M.A., & Ren, Yi. Structural basis for influenza virus NS1 protein block of mRNA nuclear export. United States. doi:10.1038/s41564-019-0482-x.
Zhang, Ke, Xie, Yihu, Muñoz-Moreno, Raquel, Wang, Juan, Zhang, Liang, Esparza, Matthew, García-Sastre, Adolfo, Fontoura, Beatriz M.A., and Ren, Yi. Wed . "Structural basis for influenza virus NS1 protein block of mRNA nuclear export". United States. doi:10.1038/s41564-019-0482-x.
@article{osti_1593437,
title = {Structural basis for influenza virus NS1 protein block of mRNA nuclear export},
author = {Zhang, Ke and Xie, Yihu and Muñoz-Moreno, Raquel and Wang, Juan and Zhang, Liang and Esparza, Matthew and García-Sastre, Adolfo and Fontoura, Beatriz M.A. and Ren, Yi},
abstractNote = {},
doi = {10.1038/s41564-019-0482-x},
journal = {Nat. Microbio.},
number = 2019,
volume = 4,
place = {United States},
year = {2020},
month = {1}
}

Works referenced in this record:

Influenza virus targets the mRNA export machinery and the nuclear pore complex
journal, January 2007

  • Satterly, N.; Tsai, P. -L.; van Deursen, J.
  • Proceedings of the National Academy of Sciences, Vol. 104, Issue 6
  • DOI: 10.1073/pnas.0610977104

Nuclear export of mRNA
journal, November 2010


Integrative structure and functional anatomy of a nuclear pore complex
journal, March 2018

  • Kim, Seung Joong; Fernandez-Martinez, Javier; Nudelman, Ilona
  • Nature, Vol. 555, Issue 7697
  • DOI: 10.1038/nature26003

Influenza Virus NS1 Protein Interacts with the Cellular 30 kDa Subunit of CPSF and Inhibits 3′ End Formation of Cellular Pre-mRNAs
journal, June 1998


The principal mRNA nuclear export factor NXF1:NXT1 forms a symmetric binding platform that facilitates export of retroviral CTE-RNA
journal, January 2015

  • Aibara, Shintaro; Katahira, Jun; Valkov, Eugene
  • Nucleic Acids Research, Vol. 43, Issue 3
  • DOI: 10.1093/nar/gkv032

Structural Basis for the Recognition of a Nucleoporin FG Repeat by the NTF2-like Domain of the TAP/p15 mRNA Nuclear Export Factor
journal, September 2001


The H5N1 Influenza Virus NS Genes Selected after 1998 Enhance Virus Replication in Mammalian Cells
journal, May 2007

  • Twu, K. Y.; Kuo, R. -L.; Marklund, J.
  • Journal of Virology, Vol. 81, Issue 15
  • DOI: 10.1128/JVI.00006-07

Structural basis for suppression of a host antiviral response by influenza A virus
journal, August 2008

  • Das, K.; Ma, L. -C.; Xiao, R.
  • Proceedings of the National Academy of Sciences, Vol. 105, Issue 35
  • DOI: 10.1073/pnas.0805213105

Influenza virus mRNA trafficking through host nuclear speckles
journal, May 2016


Cellular RNA Binding Proteins NS1-BP and hnRNP K Regulate Influenza A Virus RNA Splicing
journal, June 2013


Phaser crystallographic software
journal, July 2007

  • McCoy, Airlie J.; Grosse-Kunstleve, Ralf W.; Adams, Paul D.
  • Journal of Applied Crystallography, Vol. 40, Issue 4
  • DOI: 10.1107/S0021889807021206

Features and development of Coot
journal, March 2010

  • Emsley, P.; Lohkamp, B.; Scott, W. G.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 4
  • DOI: 10.1107/S0907444910007493

Towards automated crystallographic structure refinement with phenix.refine
journal, March 2012

  • Afonine, Pavel V.; Grosse-Kunstleve, Ralf W.; Echols, Nathaniel
  • Acta Crystallographica Section D Biological Crystallography, Vol. 68, Issue 4
  • DOI: 10.1107/S0907444912001308