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Title: Crystal structures of p120RasGAP N-terminal SH2 domain in its apo form and in complex with a p190RhoGAP phosphotyrosine peptide

Authors:
; ;  [1]
  1. Yale
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Org.:
National Institutes of Health (NIH)
OSTI Identifier:
1591894
Resource Type:
Journal Article
Journal Name:
PLoS One
Additional Journal Information:
Journal Volume: 14; Journal Issue: (12) ; 12, 2019
Country of Publication:
United States
Language:
ENGLISH

Citation Formats

Chehayeb, Rachel Jaber, Stiegler, Amy L., and Boggon, Titus J. Crystal structures of p120RasGAP N-terminal SH2 domain in its apo form and in complex with a p190RhoGAP phosphotyrosine peptide. United States: N. p., 2020. Web. doi:10.1371/journal.pone.0226113.
Chehayeb, Rachel Jaber, Stiegler, Amy L., & Boggon, Titus J. Crystal structures of p120RasGAP N-terminal SH2 domain in its apo form and in complex with a p190RhoGAP phosphotyrosine peptide. United States. doi:10.1371/journal.pone.0226113.
Chehayeb, Rachel Jaber, Stiegler, Amy L., and Boggon, Titus J. Thu . "Crystal structures of p120RasGAP N-terminal SH2 domain in its apo form and in complex with a p190RhoGAP phosphotyrosine peptide". United States. doi:10.1371/journal.pone.0226113.
@article{osti_1591894,
title = {Crystal structures of p120RasGAP N-terminal SH2 domain in its apo form and in complex with a p190RhoGAP phosphotyrosine peptide},
author = {Chehayeb, Rachel Jaber and Stiegler, Amy L. and Boggon, Titus J.},
abstractNote = {},
doi = {10.1371/journal.pone.0226113},
journal = {PLoS One},
number = (12) ; 12, 2019,
volume = 14,
place = {United States},
year = {2020},
month = {1}
}

Works referenced in this record:

Rho GTPases and the Actin Cytoskeleton
journal, January 1998


p190RhoGAP proteins contain pseudoGTPase domains
journal, September 2017


p190-B, a New Member of the Rho GAP Family, and Rho Are Induced to Cluster after Integrin Cross-linking
journal, December 1995

  • Burbelo, Peter D.; Miyamoto, Shingo; Utani, Atsushi
  • Journal of Biological Chemistry, Vol. 270, Issue 52
  • DOI: 10.1074/jbc.270.52.30919

Molecular cloning of cDNAs encoding the GAP-associated protein p190: Implications for a signaling pathway from ras to the nucleus
journal, May 1992


Adhesion-Dependent Regulation of p190RhoGAP in the Developing Brain by the Abl-Related Gene Tyrosine Kinase
journal, April 2004

  • Hernández, Samuel E.; Settleman, Jeffrey; Koleske, Anthony J.
  • Current Biology, Vol. 14, Issue 8
  • DOI: 10.1016/j.cub.2004.03.062

PhosphoSitePlus, 2014: mutations, PTMs and recalibrations
journal, December 2014

  • Hornbeck, Peter V.; Zhang, Bin; Murray, Beth
  • Nucleic Acids Research, Vol. 43, Issue D1
  • DOI: 10.1093/nar/gku1267

Discovery and saturation analysis of cancer genes across 21 tumour types
journal, January 2014

  • Lawrence, Michael S.; Stojanov, Petar; Mermel, Craig H.
  • Nature, Vol. 505, Issue 7484
  • DOI: 10.1038/nature12912

GEFs and GAPs: Critical Elements in the Control of Small G Proteins
journal, June 2007


Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas
journal, May 2016

  • Campbell, Joshua D.; Alexandrov, Anton; Kim, Jaegil
  • Nature Genetics, Vol. 48, Issue 6
  • DOI: 10.1038/ng.3564

PHENIX: a comprehensive Python-based system for macromolecular structure solution
journal, January 2010

  • Adams, Paul D.; Afonine, Pavel V.; Bunkóczi, Gábor
  • Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 2, p. 213-221
  • DOI: 10.1107/S0907444909052925

Phaser crystallographic software
journal, July 2007

  • McCoy, Airlie J.; Grosse-Kunstleve, Ralf W.; Adams, Paul D.
  • Journal of Applied Crystallography, Vol. 40, Issue 4
  • DOI: 10.1107/S0021889807021206

Iterative model building, structure refinement and density modification with the PHENIX AutoBuild wizard
journal, December 2007

  • Terwilliger, Thomas C.; Grosse-Kunstleve, Ralf W.; Afonine, Pavel V.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 64, Issue 1
  • DOI: 10.1107/S090744490705024X

Space-group and origin ambiguity in macromolecular structures with pseudo-symmetry and its treatment with the program Zanuda
journal, August 2014

  • Lebedev, Andrey A.; Isupov, Michail N.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 70, Issue 9
  • DOI: 10.1107/S1399004714014795

Features and development of Coot
journal, March 2010

  • Emsley, P.; Lohkamp, B.; Scott, W. G.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 4
  • DOI: 10.1107/S0907444910007493

MolProbity : all-atom structure validation for macromolecular crystallography
journal, December 2009

  • Chen, Vincent B.; Arendall, W. Bryan; Headd, Jeffrey J.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 1
  • DOI: 10.1107/S0907444909042073

Presenting your structures: the CCP 4 mg molecular-graphics software
journal, March 2011

  • McNicholas, S.; Potterton, E.; Wilson, K. S.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 67, Issue 4
  • DOI: 10.1107/S0907444911007281

Inference of Macromolecular Assemblies from Crystalline State
journal, September 2007


Collaboration gets the most out of software
journal, September 2013


SH2 domains recognize specific phosphopeptide sequences
journal, March 1993


Screening for phasing atoms in protein crystallography
journal, July 2000


Dali server: conservation mapping in 3D
journal, May 2010

  • Holm, Liisa; Rosenstr�m, P�ivi
  • Nucleic Acids Research, Vol. 38, Issue suppl_2
  • DOI: 10.1093/nar/gkq366

The language of SH2 domain interactions defines phosphotyrosine-mediated signal transduction
journal, May 2012


Data publication with the structural biology data grid supports live analysis
journal, March 2016

  • Meyer, Peter A.; Socias, Stephanie; Key, Jason
  • Nature Communications, Vol. 7, Issue 1
  • DOI: 10.1038/ncomms10882