skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Identification of N-Methyl Nicotinamide and N-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2)

Authors:
ORCiD logo; ; ORCiD logo; ; ; ORCiD logo; ; ; ; ; ; ; ; ; ; ; ; ; ; more »; ; ; ; ; ; ; ; ORCiD logo; « less
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Org.:
INDUSTRY
OSTI Identifier:
1577168
Resource Type:
Journal Article
Journal Name:
Journal of Medicinal Chemistry
Additional Journal Information:
Journal Volume: 62; Journal Issue: 20; Journal ID: ISSN 0022-2623
Publisher:
American Chemical Society (ACS)
Country of Publication:
United States
Language:
ENGLISH

Citation Formats

Moslin, Ryan, Zhang, Yanlei, Wrobleski, Stephen T., Lin, Shuqun, Mertzman, Michael, Spergel, Steven, Tokarski, John S., Strnad, Joann, Gillooly, Kathleen, McIntyre, Kim W., Zupa-Fernandez, Adriana, Cheng, Lihong, Sun, Huadong, Chaudhry, Charu, Huang, Christine, D’Arienzo, Celia, Heimrich, Elizabeth, Yang, Xiaoxia, Muckelbauer, Jodi K., Chang, ChiehYing, Tredup, Jeffrey, Mulligan, Dawn, Xie, Dianlin, Aranibar, Nelly, Chiney, Manoj, Burke, James R., Lombardo, Louis, Carter, Percy H., and Weinstein, David S. Identification of N-Methyl Nicotinamide and N-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2). United States: N. p., 2019. Web. doi:10.1021/acs.jmedchem.9b00443.
Moslin, Ryan, Zhang, Yanlei, Wrobleski, Stephen T., Lin, Shuqun, Mertzman, Michael, Spergel, Steven, Tokarski, John S., Strnad, Joann, Gillooly, Kathleen, McIntyre, Kim W., Zupa-Fernandez, Adriana, Cheng, Lihong, Sun, Huadong, Chaudhry, Charu, Huang, Christine, D’Arienzo, Celia, Heimrich, Elizabeth, Yang, Xiaoxia, Muckelbauer, Jodi K., Chang, ChiehYing, Tredup, Jeffrey, Mulligan, Dawn, Xie, Dianlin, Aranibar, Nelly, Chiney, Manoj, Burke, James R., Lombardo, Louis, Carter, Percy H., & Weinstein, David S. Identification of N-Methyl Nicotinamide and N-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2). United States. doi:10.1021/acs.jmedchem.9b00443.
Moslin, Ryan, Zhang, Yanlei, Wrobleski, Stephen T., Lin, Shuqun, Mertzman, Michael, Spergel, Steven, Tokarski, John S., Strnad, Joann, Gillooly, Kathleen, McIntyre, Kim W., Zupa-Fernandez, Adriana, Cheng, Lihong, Sun, Huadong, Chaudhry, Charu, Huang, Christine, D’Arienzo, Celia, Heimrich, Elizabeth, Yang, Xiaoxia, Muckelbauer, Jodi K., Chang, ChiehYing, Tredup, Jeffrey, Mulligan, Dawn, Xie, Dianlin, Aranibar, Nelly, Chiney, Manoj, Burke, James R., Lombardo, Louis, Carter, Percy H., and Weinstein, David S. Wed . "Identification of N-Methyl Nicotinamide and N-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2)". United States. doi:10.1021/acs.jmedchem.9b00443.
@article{osti_1577168,
title = {Identification of N-Methyl Nicotinamide and N-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2)},
author = {Moslin, Ryan and Zhang, Yanlei and Wrobleski, Stephen T. and Lin, Shuqun and Mertzman, Michael and Spergel, Steven and Tokarski, John S. and Strnad, Joann and Gillooly, Kathleen and McIntyre, Kim W. and Zupa-Fernandez, Adriana and Cheng, Lihong and Sun, Huadong and Chaudhry, Charu and Huang, Christine and D’Arienzo, Celia and Heimrich, Elizabeth and Yang, Xiaoxia and Muckelbauer, Jodi K. and Chang, ChiehYing and Tredup, Jeffrey and Mulligan, Dawn and Xie, Dianlin and Aranibar, Nelly and Chiney, Manoj and Burke, James R. and Lombardo, Louis and Carter, Percy H. and Weinstein, David S.},
abstractNote = {},
doi = {10.1021/acs.jmedchem.9b00443},
journal = {Journal of Medicinal Chemistry},
issn = {0022-2623},
number = 20,
volume = 62,
place = {United States},
year = {2019},
month = {7}
}