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Title: Structures of CENP-C cupin domains at regional centromeres reveal unique patterns of dimerization and recruitment functionsfor the inner pocket

Authors:
; ; ; ; ; ; ; ;  [1]
  1. Connecticut
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Org.:
National Institutes of Health (NIH)
OSTI Identifier:
1575998
Resource Type:
Journal Article
Journal Name:
J. Biol. Chem.
Additional Journal Information:
Journal Volume: 294; Journal Issue: (38) ; 09, 2019
Country of Publication:
United States
Language:
ENGLISH

Citation Formats

Chik, Jennifer K., Moiseeva, Vera, Goel, Pavitra K., Meinen, Ben A., Koldewey, Philipp, An, Sojin, Mellone, Barbara G., Subramanian, Lakxmi, Cho, Uhn-Soo, Michigan-Med), Queen Mary), and Michigan). Structures of CENP-C cupin domains at regional centromeres reveal unique patterns of dimerization and recruitment functionsfor the inner pocket. United States: N. p., 2019. Web. doi:10.1074/jbc.RA119.008464.
Chik, Jennifer K., Moiseeva, Vera, Goel, Pavitra K., Meinen, Ben A., Koldewey, Philipp, An, Sojin, Mellone, Barbara G., Subramanian, Lakxmi, Cho, Uhn-Soo, Michigan-Med), Queen Mary), & Michigan). Structures of CENP-C cupin domains at regional centromeres reveal unique patterns of dimerization and recruitment functionsfor the inner pocket. United States. doi:10.1074/jbc.RA119.008464.
Chik, Jennifer K., Moiseeva, Vera, Goel, Pavitra K., Meinen, Ben A., Koldewey, Philipp, An, Sojin, Mellone, Barbara G., Subramanian, Lakxmi, Cho, Uhn-Soo, Michigan-Med), Queen Mary), and Michigan). Thu . "Structures of CENP-C cupin domains at regional centromeres reveal unique patterns of dimerization and recruitment functionsfor the inner pocket". United States. doi:10.1074/jbc.RA119.008464.
@article{osti_1575998,
title = {Structures of CENP-C cupin domains at regional centromeres reveal unique patterns of dimerization and recruitment functionsfor the inner pocket},
author = {Chik, Jennifer K. and Moiseeva, Vera and Goel, Pavitra K. and Meinen, Ben A. and Koldewey, Philipp and An, Sojin and Mellone, Barbara G. and Subramanian, Lakxmi and Cho, Uhn-Soo and Michigan-Med) and Queen Mary) and Michigan)},
abstractNote = {},
doi = {10.1074/jbc.RA119.008464},
journal = {J. Biol. Chem.},
number = (38) ; 09, 2019,
volume = 294,
place = {United States},
year = {2019},
month = {11}
}

Works referenced in this record:

Aneuploidy: Cells Losing Their Balance
journal, June 2008


To err (meiotically) is human: the genesis of human aneuploidy
journal, April 2001

  • Hassold, Terry; Hunt, Patricia
  • Nature Reviews Genetics, Vol. 2, Issue 4
  • DOI: 10.1038/35066065

The kinetochore and cancer: what's the connection?
journal, December 2005

  • Yuen, Karen WY; Montpetit, Ben; Hieter, Philip
  • Current Opinion in Cell Biology, Vol. 17, Issue 6
  • DOI: 10.1016/j.ceb.2005.09.012

Isolation of a yeast centromere and construction of functional small circular chromosomes
journal, October 1980

  • Clarke, Louise; Carbon, John
  • Nature, Vol. 287, Issue 5782
  • DOI: 10.1038/287504a0

Nucleotide sequence comparisons and functional analysis of yeast centromere DNAs
journal, May 1982


A 125-base-pair CEN6 DNA fragment is sufficient for complete meiotic and mitotic centromere functions in Saccharomyces cerevisiae.
journal, August 1989

  • Cottarel, G.; Shero, J. H.; Hieter, P.
  • Molecular and Cellular Biology, Vol. 9, Issue 8
  • DOI: 10.1128/MCB.9.8.3342

A 240 kd multisubunit protein complex, CBF3, is a major component of the budding yeast centromere
journal, February 1991


The molecular basis for centromere identity and function
journal, November 2015

  • McKinley, Kara L.; Cheeseman, Iain M.
  • Nature Reviews Molecular Cell Biology, Vol. 17, Issue 1
  • DOI: 10.1038/nrm.2015.5

The fine structure of the kinetochore of a mammalian cell in vitro
journal, January 1966

  • Brinkley, B. R.; Stubblefield, Elton
  • Chromosoma, Vol. 19, Issue 1
  • DOI: 10.1007/BF00332792

Molecular architecture of the kinetochore–microtubule interface
journal, January 2008

  • Cheeseman, Iain M.; Desai, Arshad
  • Nature Reviews Molecular Cell Biology, Vol. 9, Issue 1
  • DOI: 10.1038/nrm2310

The Conserved KMN Network Constitutes the Core Microtubule-Binding Site of the Kinetochore
journal, December 2006


Identification of a family of human centromere proteins using autoimmune sera from patients with scleroderma
journal, January 1985

  • Earnshaw, William C.; Rothfield, Naomi
  • Chromosoma, Vol. 91, Issue 3-4
  • DOI: 10.1007/BF00328227

Autoantibody to centromere (kinetochore) in scleroderma sera.
journal, March 1980

  • Moroi, Y.; Peebles, C.; Fritzler, M. J.
  • Proceedings of the National Academy of Sciences, Vol. 77, Issue 3
  • DOI: 10.1073/pnas.77.3.1627

Dual recognition of CENP-A nucleosomes is required for centromere assembly
journal, June 2010

  • Carroll, Christopher W.; Milks, Kirstin J.; Straight, Aaron F.
  • The Journal of Cell Biology, Vol. 189, Issue 7
  • DOI: 10.1083/jcb.201001013

A Conserved Mechanism for Centromeric Nucleosome Recognition by Centromere Protein CENP-C
journal, May 2013


The CENP-L-N Complex Forms a Critical Node in an Integrated Meshwork of Interactions at the Centromere-Kinetochore Interface
journal, December 2015


The Kinetochore and the Centromere: A Working Long Distance Relationship
journal, December 2009


Evolutionary Turnover of Kinetochore Proteins: A Ship of Theseus?
journal, July 2016

  • Drinnenberg, Ines A.; Henikoff, Steven; Malik, Harmit S.
  • Trends in Cell Biology, Vol. 26, Issue 7
  • DOI: 10.1016/j.tcb.2016.01.005

Direct Binding of Cenp-C to the Mis12 Complex Joins the Inner and Outer Kinetochore
journal, March 2011

  • Screpanti, Emanuela; De Antoni, Anna; Alushin, Gregory M.
  • Current Biology, Vol. 21, Issue 5
  • DOI: 10.1016/j.cub.2010.12.039

CENP-C Is a Structural Platform for Kinetochore Assembly
journal, March 2011

  • Przewloka, Marcin R.; Venkei, Zsolt; Bolanos-Garcia, Victor M.
  • Current Biology, Vol. 21, Issue 5
  • DOI: 10.1016/j.cub.2011.02.005

CENP-C is a blueprint for constitutive centromere–associated network assembly within human kinetochores
journal, June 2015

  • Klare, Kerstin; Weir, John R.; Basilico, Federica
  • The Journal of Cell Biology, Vol. 210, Issue 1
  • DOI: 10.1083/jcb.201412028

Dynamic changes in CCAN organization through CENP-C during cell-cycle progression
journal, November 2015

  • Nagpal, Harsh; Hori, Tetsuya; Furukawa, Ayako
  • Molecular Biology of the Cell, Vol. 26, Issue 21
  • DOI: 10.1091/mbc.E15-07-0531

CENP-C Functions as a Scaffold for Effectors with Essential Kinetochore Functions in Mitosis and Meiosis
journal, September 2009


An Iml3-Chl4 Heterodimer Links the Core Centromere to Factors Required for Accurate Chromosome Segregation
journal, October 2013


Structural and Functional Dissection of Mif2p, a Conserved DNA-binding Kinetochore Protein
journal, October 2008

  • Cohen, R. L.; Espelin, C. W.; De Wulf, P.
  • Molecular Biology of the Cell, Vol. 19, Issue 10
  • DOI: 10.1091/mbc.E08-03-0297

The Kinetochore Protein Moa1 Enables Cohesion-Mediated Monopolar Attachment at Meiosis I
journal, December 2005


Meikin is a conserved regulator of meiosis-I-specific kinetochore function
journal, December 2014

  • Kim, Jihye; Ishiguro, Kei-ichiro; Nambu, Aya
  • Nature, Vol. 517, Issue 7535
  • DOI: 10.1038/nature14097

Meikin-associated polo-like kinase specifies Bub1 distribution in meiosis I
journal, May 2017

  • Miyazaki, Seira; Kim, Jihye; Yamagishi, Yuya
  • Genes to Cells, Vol. 22, Issue 6
  • DOI: 10.1111/gtc.12496

Crystal Structure of Human Pirin: AN IRON-BINDING NUCLEAR PROTEIN AND TRANSCRIPTION COFACTOR
journal, October 2003

  • Pang, Hai; Bartlam, Mark; Zeng, Qinghong
  • Journal of Biological Chemistry, Vol. 279, Issue 2
  • DOI: 10.1074/jbc.M310022200

Crystal Structure of Mammalian Cysteine Dioxygenase: A NOVEL MONONUCLEAR IRON CENTER FOR CYSTEINE THIOL OXIDATION
journal, April 2006

  • Simmons, Chad R.; Liu, Qun; Huang, Qingqiu
  • Journal of Biological Chemistry, Vol. 281, Issue 27
  • DOI: 10.1074/jbc.M601555200

Role of Bacillus subtilis BacB in the Synthesis of Bacilysin
journal, September 2009

  • Rajavel, Malligarjunan; Mitra, Ashima; Gopal, Balasubramanian
  • Journal of Biological Chemistry, Vol. 284, Issue 46
  • DOI: 10.1074/jbc.M109.014522

Inference of Macromolecular Assemblies from Crystalline State
journal, September 2007


Centromere identity is specified by a single centromeric nucleosome in budding yeast
journal, September 2007

  • Furuyama, S.; Biggins, S.
  • Proceedings of the National Academy of Sciences, Vol. 104, Issue 37
  • DOI: 10.1073/pnas.0706985104

Conserved Organization of Centromeric Chromatin in Flies and Humans
journal, March 2002


Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore: H3K4me2 and kinetochore maintenance
journal, December 2010

  • Bergmann, Jan H.; Rodríguez, Mariluz Gómez; Martins, Nuno M. C.
  • The EMBO Journal, Vol. 30, Issue 2
  • DOI: 10.1038/emboj.2010.329

Three-dimensional localization of CENP-A suggests a complex higher order structure of centromeric chromatin
journal, December 2008

  • Marshall, Owen J.; Marshall, Alan T.; Choo, K. H. Andy
  • The Journal of Cell Biology, Vol. 183, Issue 7
  • DOI: 10.1083/jcb.200804078

The Centromere: Chromatin Foundation for the Kinetochore Machinery
journal, September 2014


Mapping the assembly pathways that specify formation of the trilaminar kinetochore plates in human cells
journal, October 2006

  • Liu, Song-Tao; Rattner, Jerome B.; Jablonski, Sandra A.
  • The Journal of Cell Biology, Vol. 175, Issue 1
  • DOI: 10.1083/jcb.200606020

Structural Basis for Ligand-Regulated Oligomerization of AraC
journal, April 1997


Detrimental incorporation of excess Cenp-A/Cid and Cenp-C into Drosophila centromeres is prevented by limiting amounts of the bridging factor Cal1
journal, October 2010

  • Schittenhelm, R. B.; Althoff, F.; Heidmann, S.
  • Journal of Cell Science, Vol. 123, Issue 21
  • DOI: 10.1242/jcs.067934

Protein production by auto-induction in high-density shaking cultures
journal, May 2005


Integration, scaling, space-group assignment and post-refinement
journal, January 2010

  • Kabsch, Wolfgang
  • Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 2, p. 133-144
  • DOI: 10.1107/S0907444909047374

XDS
journal, January 2010

  • Kabsch, Wolfgang
  • Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 2
  • DOI: 10.1107/S0907444909047337

Decision-making in structure solution using Bayesian estimates of map quality: the PHENIX AutoSol wizard
journal, May 2009

  • Terwilliger, Thomas C.; Adams, Paul D.; Read, Randy J.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 65, Issue 6
  • DOI: 10.1107/S0907444909012098

Iterative model building, structure refinement and density modification with the PHENIX AutoBuild wizard
journal, December 2007

  • Terwilliger, Thomas C.; Grosse-Kunstleve, Ralf W.; Afonine, Pavel V.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 64, Issue 1
  • DOI: 10.1107/S090744490705024X

Features and development of Coot
journal, March 2010

  • Emsley, P.; Lohkamp, B.; Scott, W. G.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 4
  • DOI: 10.1107/S0907444910007493

PHENIX: a comprehensive Python-based system for macromolecular structure solution
journal, January 2010

  • Adams, Paul D.; Afonine, Pavel V.; Bunkóczi, Gábor
  • Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 2, p. 213-221
  • DOI: 10.1107/S0907444909052925

MolProbity : all-atom structure validation for macromolecular crystallography
journal, December 2009

  • Chen, Vincent B.; Arendall, W. Bryan; Headd, Jeffrey J.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 1
  • DOI: 10.1107/S0907444909042073

iMOSFLM : a new graphical interface for diffraction-image processing with MOSFLM
journal, March 2011

  • Battye, T. Geoff G.; Kontogiannis, Luke; Johnson, Owen
  • Acta Crystallographica Section D Biological Crystallography, Vol. 67, Issue 4
  • DOI: 10.1107/S0907444910048675

How good are my data and what is the resolution?
journal, June 2013

  • Evans, Philip R.; Murshudov, Garib N.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 69, Issue 7
  • DOI: 10.1107/S0907444913000061

Phaser crystallographic software
journal, July 2007

  • McCoy, Airlie J.; Grosse-Kunstleve, Ralf W.; Adams, Paul D.
  • Journal of Applied Crystallography, Vol. 40, Issue 4
  • DOI: 10.1107/S0021889807021206

NIH Image to ImageJ: 25 years of image analysis
journal, June 2012

  • Schneider, Caroline A.; Rasband, Wayne S.; Eliceiri, Kevin W.
  • Nature Methods, Vol. 9, Issue 7
  • DOI: 10.1038/nmeth.2089

A two-dimensional spectrum analysis for sedimentation velocity experiments of mixtures with heterogeneity in molecular weight and shape
journal, February 2009

  • Brookes, Emre; Cao, Weiming; Demeler, Borries
  • European Biophysics Journal, Vol. 39, Issue 3, p. 405-414
  • DOI: 10.1007/s00249-009-0413-5

The fission yeast nucleoporin Alm1 is required for proteasomal degradation of kinetochore components
journal, October 2017

  • Salas-Pino, Silvia; Gallardo, Paola; Barrales, Ramón R.
  • The Journal of Cell Biology, Vol. 216, Issue 11
  • DOI: 10.1083/jcb.201612194

Eic1 links Mis18 with the CCAN/Mis6/Ctf19 complex to promote CENP-A assembly
journal, April 2014

  • Subramanian, Lakxmi; Toda, Nicholas R. T.; Rappsilber, Juri
  • Open Biology, Vol. 4, Issue 4
  • DOI: 10.1098/rsob.140043