skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Methods and apparatus for preparing aqueous specimens for electron microscopy using volatile surfactants

Abstract

This disclosure provides systems, methods, and apparatus related to the preparation of electron microscopy specimens. In one aspect, a method includes providing an electron microscopy grid. An aqueous suspension including an electron microscopy sample is deposited on the electron microscopy grid. A portion of the aqueous suspension is removed from the electron microscopy grid. A volatile surfactant is contacted to the aqueous suspension. A thickness of aqueous suspension is allowed to decrease over a period of time. The aqueous suspension is then frozen.

Inventors:
;
Publication Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1568428
Patent Number(s):
10,309,881
Application Number:
15/194,777
Assignee:
The Regents of the University of California (Oakland, CA)
DOE Contract Number:  
AC02-05CH11231; GM083039
Resource Type:
Patent
Resource Relation:
Patent File Date: 06/28/2016
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Glaeser, Robert M., and Han, Bong-Gyoon. Methods and apparatus for preparing aqueous specimens for electron microscopy using volatile surfactants. United States: N. p., 2019. Web.
Glaeser, Robert M., & Han, Bong-Gyoon. Methods and apparatus for preparing aqueous specimens for electron microscopy using volatile surfactants. United States.
Glaeser, Robert M., and Han, Bong-Gyoon. Tue . "Methods and apparatus for preparing aqueous specimens for electron microscopy using volatile surfactants". United States. https://www.osti.gov/servlets/purl/1568428.
@article{osti_1568428,
title = {Methods and apparatus for preparing aqueous specimens for electron microscopy using volatile surfactants},
author = {Glaeser, Robert M. and Han, Bong-Gyoon},
abstractNote = {This disclosure provides systems, methods, and apparatus related to the preparation of electron microscopy specimens. In one aspect, a method includes providing an electron microscopy grid. An aqueous suspension including an electron microscopy sample is deposited on the electron microscopy grid. A portion of the aqueous suspension is removed from the electron microscopy grid. A volatile surfactant is contacted to the aqueous suspension. A thickness of aqueous suspension is allowed to decrease over a period of time. The aqueous suspension is then frozen.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2019},
month = {6}
}

Patent:

Save / Share:

Works referenced in this record: