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U.S. Department of Energy
Office of Scientific and Technical Information

Methods for generating barcoded combinatorial libraries

Patent ·
OSTI ID:1568324

Provided herein are methods and composition for trackable genetic variant libraries. Further provided herein are methods and compositions for recursive engineering. Further provided herein are methods and compositions for multiplex engineering. Further provided herein are methods and compositions for enriching for editing and trackable engineered sequences and cells using nucleic acid-guided nucleases.

Research Organization:
Univ. of Colorado, Denver, CO (United States); Inscripta, Inc., Boulder, CO (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
SC0008812
Assignee:
The Regents of the University of Colorado, a body corporate (Denver, CO); Inscripta, Inc. (Boulder, CO)
Patent Number(s):
10,287,575
Application Number:
15/948,798
OSTI ID:
1568324
Country of Publication:
United States
Language:
English